EVALUATION OF CARDIAC AUTONOMIC DYSFUNCTION AND THE RISK OF ARRHYTHMIA IN CHILDREN WITH MITRAL VALVE PROLAPSE
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Tarih
2023
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info:eu-repo/semantics/openAccess
Özet
Objective: The occurrence of symptoms in patients with mitral valve prolapse (MVP) is linked to autonomic dysfunction and neuroendocrine causes rather than progressive mitral valve insufficiency. The goal was to assess the risk of autonomic dysfunction and arrhythmia in patients with MVP. Methods: A cohort of 63 individuals with MVP was compared to a control group of 64 age- and gender-matched children. A comprehensive assessment was conducted, comprising physical examination, medical history taking, and various diagnostic tests, including 12-lead electrocardiography, autonomic function testing, echocardiography, and 24-hour Holter rhythm monitoring. Results: In comparison to the control group, the MVP group had higher QTc dispersion, frontal QRS-T angle, Tp-e interval, and Tp-e/QTc ratio at rest. However, conventional measurements of heart rate variability in the Holter ECG or HRDC, a novel and understudied parameter in children, did not significantly differ between the two groups. Conclusion: Although cases with pathological findings in the initial ECG were excluded from our study, the widened frontal QRS-T angle seen in MVP patients is a novel finding, and that when compared to the control group, these patients' HRDC doesn't seem to differ noticeably.
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Acta Medica Nicomedia
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Cilt
6
Sayı
2
