Echocardiographic prediction of long-term response to biventricular pacemaker in severe heart failure

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dc.authoridDagdeviren, Bahadir/0000-0001-6945-0745
dc.authorwosidDagdeviren, Bahadir/J-5016-2012
dc.contributor.authorOguz, E
dc.contributor.authorDagdeviren, B
dc.contributor.authorBilsel, T
dc.contributor.authorAkdemir, O
dc.contributor.authorErdinler, I
dc.contributor.authorAkyol, A
dc.contributor.authorUlufer, T
dc.date.accessioned2024-06-12T10:54:45Z
dc.date.available2024-06-12T10:54:45Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.descriptionHeart Failure 2000 Conference -- JUN 29-JUL 01, 2000 -- VENICE, ITALYen_US
dc.description.abstractBackground: Biventricular pacing substantially improves LV systolic function and symptom status in some patients with dilated cardiomyopathy. Aims: To assess whether the long-term benefit could be predicted from the echocardiographic parameters. Methods and Results: Sixteen patients with dilated cardiomyopathy who underwent atrio-biventricular pacemaker implantation were analyzed in two groups: the responders (n = 11) were those with a symptomatic improvement of one or more NYHA functional class; the non-responders (n = 5) failed to improve at follow-up (7.6 +/- 5 months). Echocardiography was performed at baseline, the day after the implantation and then every 3 months. Besides the conventional parameters, the following variables were included: LV diastolic filling time (DFT); the duration of mitral regurgitation (dMR); and LV dP/dt obtained from the continuous wave mitral regurgitation curve. While the baseline DFT and dP/dt were not significantly different between non-responders and responders (256 +/- 105 vs. 358 +/- 115, P = 0.14 and 564 +/- 199 vs. 468 +/- 117, P = 0.44, respectively), the QRS width (149 +/- 15 vs. 175 +/- 24 ms, P = 0.05) and the dMR (343 +/- 70 vs. 443 +/- 49 ms, P = 0.007) were higher in the responders. The changes of dMR, DFT and QRS width by pacing were not significantly different between groups (P = 0.18, 0.30 and 0.77, respectively). However, the change of LV dP/dt by pacing in the responders was significantly different than for non-responders (from 468 +/- 117 to 676 +/- 216 mmHg/s vs. from 564 +/- 199 to 483 +/- 94, P = 0.002). An acute increase in LV dP/dt over 22% by pacing yielded only two false negatives and no false positives in predicting the long-term responsiveness. Conclusion: Patients with longer QRS and dMR are more likely to benefit from atrio-biventricular stimulation. The acute changes of Doppler derived LV dP/dt may provide valuable information in predicting the long-term response to biventricular pacing. (C) 2002 European Society of Cardiology. All rights reserved.en_US
dc.identifier.doi10.1016/S1388-9842(01)00188-X
dc.identifier.endpage90en_US
dc.identifier.issn1388-9842
dc.identifier.issue1en_US
dc.identifier.pmid11812668en_US
dc.identifier.scopus2-s2.0-0036154727en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.1016/S1388-9842(01)00188-X
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19171
dc.identifier.volume4en_US
dc.identifier.wosWOS:000174083000011en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal Of Heart Failureen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiventricular Pacingen_US
dc.subjectEchocardiographyen_US
dc.subjectHeart Failureen_US
dc.subjectDilated Cardiomyopathyen_US
dc.subjectAtrioventricular Delayen_US
dc.subjectConduction Delayen_US
dc.subjectChamberen_US
dc.subjectDoppleren_US
dc.subjectCatheterizationen_US
dc.subjectImprovementen_US
dc.subjectInsyncen_US
dc.titleEchocardiographic prediction of long-term response to biventricular pacemaker in severe heart failureen_US
dc.typeConference Objecten_US

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