Deceased donor kidney allocation schemes and international exchange
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose of review In this review, we summarize different allocation schemes around the world and identify ways to exchange organs between countries. Recent findings The primary goal of transplantation is prolongation of patient survival and an improved quality of life. Most allocation systems try to match the potential survival of the organ with the life expectancy of its recipient. Kidney transplantation enables cost reductions by the avoidance of dialysis for the healthcare system, which is sometimes the driving force for state interventions to enhance donor recruitment The major benefit from international exchange is the possibility to transplant highly sensitized patients or patients with rare HLA allele. In a broad international exchange system, there are three possibilities: exchange of surplus organs, exchange of organs to support patients with a potentially excessive waiting time because of HLA antibodies or rare alleles, and exchange of organs to make the best possible match between donor and recipient. It is possible to shape a hierarchical allocation scheme, which could be applicable in the majority of populations despite different geographical and socioeconomic conditions: allocation to recipients with special requirements (high-urgency, highly sensitized); identification of a within the region/country; in case no suitable recipient can be identified, offer countrywide or between countries; for every organ transferred to another country, there must be an obligation to give one back.
Açıklama
Anahtar Kelimeler
Age, Allocation, Ischemia, Kidney Transplantation, Waiting List, Graft Failure, Urgency Priority, United-States, Hla Mismatch, Waiting Time, Transplantation, Outcomes, Risk, Mortality, Dialysis
Kaynak
Current Opinion In Organ Transplantation
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
25
Sayı
1
