Validity of serum tau protein levels in pediatric patients with minor head trauma

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dc.authoridAylanc, Hakan/0000-0002-8907-3809
dc.authoridHicdonmez, Tufan/0000-0003-4847-8727;
dc.authorwosidAylanc, Hakan/HKV-4794-2023
dc.authorwosidAylanç, Hakan/I-4373-2019
dc.authorwosidHicdonmez, Tufan/AGI-0165-2022
dc.authorwosidGuzel, Ahmet/AGE-2880-2022
dc.contributor.authorGuzel, Ahmet
dc.contributor.authorKarasalihoglu, Serap
dc.contributor.authorAylanc, Hakan
dc.contributor.authorTemizoz, Osman
dc.contributor.authorHicdonmez, Tufan
dc.date.accessioned2024-06-12T11:19:28Z
dc.date.available2024-06-12T11:19:28Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to investigate the relationship between intracranial injury and serum tau protein levels in pediatric patients with minor head trauma (NI HT). Methods: We included 60 pediatric patients with MELT (Glasgow Coma Scale [GCS], 14-15) and 28 control patients. The patients were divided into 3 groups as follows: those without (group 1) and with (group 2) intracranial lesions shown on cranial computed tomography (CCT) and the control group (group 3). Results: The mean serum tau protein level was 96.06 +/- 70.36 pg/mL in group I. whereas it was 112.04 +/- 52.66 pg/mL in group 2, with no statistically significant difference between the groups (p = .160). The mean serum tau protein levels between the study groups (group I and group 2) and control (38.52 +/- 29.01) were statistically significant (P < .001 and P < .001, respectively). The GCS score and pathologic condition in CCT were only influential variables on tau protein levels. Conclusions: We found that serum tau protein increased after M HT but did not distinguish between those with and those without intracranial lesions demonstrable on CCT. (C) 2010 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2008.12.025
dc.identifier.endpage403en_US
dc.identifier.issn0735-6757
dc.identifier.issue4en_US
dc.identifier.pmid20466216en_US
dc.identifier.scopus2-s2.0-77951892701en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage399en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2008.12.025
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25205
dc.identifier.volume28en_US
dc.identifier.wosWOS:000277984800002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeuron-Specific Enolaseen_US
dc.subjectBrain-Injuryen_US
dc.subjectChildrenen_US
dc.subjectInterleukin-6en_US
dc.subjectSeverityen_US
dc.subjectS100ben_US
dc.subjectRuleen_US
dc.titleValidity of serum tau protein levels in pediatric patients with minor head traumaen_US
dc.typeArticleen_US

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