Nasal hemangiopericytoma presenting with oncogenic osteomalasia: A case report and literature review

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dc.authoridCelik, Mehmet/0000-0001-7364-370X
dc.authoridGokyer, Ali/0000-0002-1653-6155
dc.authoridSayin, Sezin/0000-0001-7892-5992
dc.authorwosidKüçükarda, Ahmet/AGF-2120-2022
dc.authorwosidCelik, Mehmet/AAA-8773-2021
dc.contributor.authorGokyer, Ali
dc.contributor.authorSayin, Sezin
dc.contributor.authorKucukarda, Ahmet
dc.contributor.authorCelik, Mehmet
dc.contributor.authorGuldiken, Sibel
dc.contributor.authorCicin, Irfan
dc.date.accessioned2024-06-12T11:09:00Z
dc.date.available2024-06-12T11:09:00Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractSinonasal type hemangiopericytoma is a rare soft tissue tumor. Oncogenic osteomalacia (tumor-induced osteomalacia) is a rare syndrome that develops especially due to benign mesenchymal tumors. Nonspecific general bone pain and weakness delay the diagnosis and treatment of oncogenic osteomalacia, and it is difficult to determine the localization of the primary tumor causing oncogenic osteomalacia. A 43-year-old male patient with nasal hemangiopericytoma with symptoms of oncogenic osteomalacia is presented. The patient had musculoskeletal complaints at first and was diagnosed with lumbar disc herniation and surgery was performed. When his complaints recurred 1 year later, he was re-evaluated and diagnosed with hypophosphatemic osteomalacia. Despite the various treatments he received, his complaints did not decrease but increased, so a detailed examination was decided. When the positive PHEX mutation and very high fibroblast growth factor 23 level were detected, PET-CT imaging was performed with a pre diagnosis of possible oncogenic osteomalacia, but no finding was found. Then he was evaluated with Ga68 DOTATATE, and the soft tissue mass filling the right ethmoidal sinus was detected. Due to the relation of the mass with surrounding structures, it was considered unsuitable for total excision and incomplete surgical excision was performed. Pathologic evaluation revealed sinonasal type hemangiopericytoma (glomangiopericytoma). A significant remission in the patient's complaints was observed after the operation. Young patients with osteomalacia with unknown causes should be evaluated for malignancy, and screening and further examinations should be performed. (c) 2020 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.currproblcancer.2020.100704
dc.identifier.issn0147-0272
dc.identifier.issn1535-6345
dc.identifier.issue3en_US
dc.identifier.pmid33446319en_US
dc.identifier.scopus2-s2.0-85099345614en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.currproblcancer.2020.100704
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22648
dc.identifier.volume45en_US
dc.identifier.wosWOS:000640527900012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.ispartofCurrent Problems In Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNasal Hemangiopericytomaen_US
dc.subjectOncogenic Osteomalaciaen_US
dc.subjectFibroblast Growth Factor 23en_US
dc.subjectSinonasal-Type Hemangiopericytomaen_US
dc.subjectTumoren_US
dc.titleNasal hemangiopericytoma presenting with oncogenic osteomalasia: A case report and literature reviewen_US
dc.typeArticleen_US

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