COMPARISON OF CLINICO PATHOLOGICAL FEATURES IN INCIDENTAL AND NONINCIDENTAL PAPILLARY THYROID CARCINOMAS IN 308 PATIENTS

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dc.authoridAytürk Salt, Semra/0000-0002-1560-3459
dc.authoridyılmaz bülbül, buket/0000-0003-2651-0036
dc.authoridCelik, Mehmet/0000-0001-7364-370X;
dc.authorwosidAytürk Salt, Semra/U-4265-2017
dc.authorwosidCan, Nuray/D-3452-2016
dc.authorwosidyılmaz bülbül, buket/JVZ-4676-2024
dc.authorwosidCelik, Mehmet/AAA-8773-2021
dc.authorwosidOzyilmaz, Filiz/A-4865-2016
dc.contributor.authorCan, Nuray
dc.contributor.authorOzyilmaz, Filiz
dc.contributor.authorCelik, Mehmet
dc.contributor.authorSezer, Atakan Y.
dc.contributor.authorSut, Necdet
dc.contributor.authorTastekin, Ebru
dc.contributor.authorAyturk, Semra
dc.date.accessioned2024-06-12T11:07:09Z
dc.date.available2024-06-12T11:07:09Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIncidental papillary thyroid carcinomas (IPTCs) consist of a significant portion of increasing incidence in papillary thyroid carcinomas. This study investigated the clinicopathological features of IPTCs from different perspectives and by comparing nonincidental PTCs (NIPTCs) in patients who underwent total thyroidectomy and lymph node dissection. Basic results were as follows. IPTC was present in 27.9% of 308 patients. IPTCs were significantly accompanied by lymphocytic thyroiditis (LT), particularly, multinodular hyperplasia (MNH). IPTCs were more common in older patients (51.3 years vs. 47.2 years) and in female patients. IPTCs significantly differed from NIPTCs in terms of smaller tumour size, lymphatic vessel invasion (2.6% vs. 97.4%), extrathyroidal extension (4.3% vs. 95.7%), lymph node metastasis (3.6% vs. 96.4%), multifocality (21.2% vs. 78.8%), bilaterality (5.3% vs. 94.7%), and BRAFV600 mutation (6.7% vs. 93.3%). Older age, bilaterality, encapsulation, and radioactive iodine (RAI) were significantly more common in IPTCs > 5 mm than in those <= 5 mm. In conclusion, IPTCs are more commonly associated with LT and MNH. IPTCs may have a more favourable prognosis than NIPTCs, and tumour size > 5 mm may predict bilaterality and need for RAI. Nevertheless, the patient-based clinical approach in IPTCs may have benefits in the management of IPTCs.en_US
dc.identifier.doi10.5114/PJP.2017.71527
dc.identifier.endpage209en_US
dc.identifier.issn1233-9687
dc.identifier.issue3en_US
dc.identifier.pmid29363911en_US
dc.identifier.scopus2-s2.0-85036661246en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://doi.org/10.5114/PJP.2017.71527
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21927
dc.identifier.volume68en_US
dc.identifier.wosWOS:000416753900002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVesalius Univ Medical Publen_US
dc.relation.ispartofPolish Journal Of Pathologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIncidental Papillary Thyroid Carcinomaen_US
dc.subjectNonincidental Papillary Thyroid Carcinomaen_US
dc.subjectClinicopathological Featureen_US
dc.subjectMicrocarcinomaen_US
dc.subjectCanceren_US
dc.subjectManagementen_US
dc.subjectExperienceen_US
dc.subjectDiseaseen_US
dc.subjectNodulesen_US
dc.subjectSurgeryen_US
dc.subjectSeriesen_US
dc.titleCOMPARISON OF CLINICO PATHOLOGICAL FEATURES IN INCIDENTAL AND NONINCIDENTAL PAPILLARY THYROID CARCINOMAS IN 308 PATIENTSen_US
dc.typeArticleen_US

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