Nerve growth factor (NGF) and NGF mRNA change in rat uterus during pregnancy

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dc.contributor.authorVarol, FG
dc.contributor.authorDuchemin, AM
dc.contributor.authorNeff, NH
dc.contributor.authorHadjiconstantinou, M
dc.date.accessioned2024-06-12T11:09:04Z
dc.date.available2024-06-12T11:09:04Z
dc.date.issued2000
dc.departmentTrakya Üniversitesien_US
dc.description.abstractDuring pregnancy, the uterus undergoes a profound sympathetic denervation. To explore whether this is associated with changes in neurotrophic factors, we assayed nerve growth factor (NGF) and NGF mRNA in the uterus of non-pregnant and pregnant rats. In the uterine horn, the concentration of NGF and its mRNA decreased during middle and late pregnancy. However, when values were corrected for the increase of uterine weight and total RNA yield during pregnancy, NGF content and mRNA per horn increased during middle and late pregnancy. Similar, but less pronounced, changes were observed in the cervix. By seven days postpartum, both parameters returned to near normal. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/S0304-3940(00)01533-0
dc.identifier.endpage62en_US
dc.identifier.issn0304-3940
dc.identifier.issue1en_US
dc.identifier.pmid11044586en_US
dc.identifier.scopus2-s2.0-0034634739en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage58en_US
dc.identifier.urihttps://doi.org/10.1016/S0304-3940(00)01533-0
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22679
dc.identifier.volume294en_US
dc.identifier.wosWOS:000165075900015en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ireland Ltden_US
dc.relation.ispartofNeuroscience Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNerve Growth Factoren_US
dc.subjectNerve Growth Factor Mrnaen_US
dc.subjectUterusen_US
dc.subjectPregnancyen_US
dc.subjectSympathetic Neuronsen_US
dc.subjectDenervationen_US
dc.subjectVascular Smooth-Muscleen_US
dc.subjectUrinary-Bladderen_US
dc.subjectMessenger-Rnaen_US
dc.subjectReceptorsen_US
dc.subjectEstrogenen_US
dc.subjectCellsen_US
dc.subjectDegenerationen_US
dc.titleNerve growth factor (NGF) and NGF mRNA change in rat uterus during pregnancyen_US
dc.typeArticleen_US

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