The Inflammation-Based Glasgow Prognostic Score as a Prognostic Factor in Patients with Intensive Cardiovascular Care Unit

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dc.authoridCakir, Banu/0000-0001-6645-6527
dc.authoridKARDAS, FATiH/0000-0001-7370-3960
dc.authoridGURDOGAN, Muhammet/0000-0001-5650-9066
dc.authoridAltay, Servet/0000-0001-7112-3970
dc.authorwosidCakir, Banu/AAC-6603-2022
dc.authorwosidKARDAS, FATiH/JOK-3455-2023
dc.authorwosidKeskin, Muhammed/W-8229-2018
dc.authorwosidAltay, Servet/C-1387-2018
dc.contributor.authorAltay, Servet
dc.contributor.authorGurdogan, Muhammet
dc.contributor.authorKeskin, Muhammed
dc.contributor.authorKardas, Fatih
dc.contributor.authorCakir, Burcu
dc.date.accessioned2024-06-12T11:02:39Z
dc.date.available2024-06-12T11:02:39Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: The Glasgow prognostic score (GPS), which is obtained from a combination of C-reactive protein (CRP) and serum albumin level, predicts poor prognoses in many cancer types. Systemic inflammation also plays an important role in pathogenesis of cardiovascular diseases. In this study, we aimed to investigate the effect of inflammation-based GPS on in-hospital and long-term outcomes in patients hospitalized in intensive cardiovascular care unit (ICCU). Methods: A total of 1004 consecutive patients admitted to ICCU were included in the study, and patients were divided into three groups based on albumin and CRP values as GPS 0, 1, and 2. Patients' demographic, clinic, and laboratory findings were recorded. In-hospital and one-year mortality rates were compared between groups. Results: Mortality occurred in 109 (10.8%) patients in in-hospital period, 82 (8.1%) patients during follow-up period, and thus, cumulative mortality occurred in 191 (19.0%) patients. Patients with a high GPS score had a higher rate of comorbidities and represented increased inflammatory evidence. In the multivariate regression model there was independent association with in-hospital mortality in GPS 1 patients compared to GPS 0 patients (Odds ratio, (OR); 5.52, 95% CI: 1.2-16.91, p = 0.025) and in GPS 2 patients compared to GPS 0 patients (OR; 7.01, 95% CI: 1.39-35.15, p = 0.018). A higher GPS score was also associated with a prolonged ICCU and hospital stay, and increased re-hospitalization in the follow-up period. Conclusion: Inflammation based GPS is a practical tool in the prediction of worse prognosis both in in-hospital and one-year follow-up periods in ICCU patients.en_US
dc.identifier.doi10.3390/medicina55050139
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue5en_US
dc.identifier.pmid31096693en_US
dc.identifier.scopus2-s2.0-85066822282en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/medicina55050139
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21368
dc.identifier.volume55en_US
dc.identifier.wosWOS:000472666200024en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMedicina-Lithuaniaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGlasgow Prognostic Scoreen_US
dc.subjectAlbuminen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectInflammationen_US
dc.subjectMortalityen_US
dc.subjectSt-Segment Elevationen_US
dc.subjectAcute Myocardial-Infarctionen_US
dc.subjectHeart-Failureen_US
dc.subjectSerum-Albuminen_US
dc.subjectSurvivalen_US
dc.subjectCanceren_US
dc.subjectGuidelinesen_US
dc.subjectPredictoren_US
dc.subjectMortalityen_US
dc.subjectIndicatoren_US
dc.titleThe Inflammation-Based Glasgow Prognostic Score as a Prognostic Factor in Patients with Intensive Cardiovascular Care Uniten_US
dc.typeArticleen_US

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