Comparing pulse pressure variation and pleth variability index in the semi-recumbent and trendelenburg position in critically ill septic patients

dc.authoridKaradayi, Selman/0000-0001-9321-075X
dc.authorwosidKaradayi, Selman/GXH-2523-2022
dc.contributor.authorKaradayi, Selman
dc.contributor.authorKaramanlioglu, Beyhan
dc.contributor.authorMemis, Dilek
dc.contributor.authorInal, Mehmet Turan
dc.contributor.authorTuran, F. Nesrin
dc.date.accessioned2024-06-12T11:13:09Z
dc.date.available2024-06-12T11:13:09Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction. Dynamic tests for predicting fluid responsiveness have generated increased interest in recent years. One of these tests, pulse pressure variation (PPV), is a parameter calculated from respiratory variations of pulse pressure. Another test, pleth variability index (PVI), is based on respiratory variations of the perfusion index and can be measured non-invasively by pulse oximeter. Previous studies have shown that both tests are valuable in determining fluid responsiveness. Methods. In this observational prospective study, our aim was to compare the PVI and PPV in order to identify a convenient tool for determining fluid responsiveness. Our study was performed in a surgical and reanimation intensive care unit. We enrolled one hundred mechanically ventilated adult patients diagnosed with sepsis. Exclusion criteria included brain death, spontaneous breathing, cardiac arrhythmia, and impaired peripheral circulation. We measured the PPV by arterial monitorization and the PVI by using Masimo Radical 7 in the 45 degrees semi-recumbent position (SP) and then 15 degrees Trendelenbug position (TP). We performed correlation and ROC analysis using a >13% fluid responsiveness cut-off value for the PPV and >14% for the PVI. Results. Between the SP and the TP, we did not observe significant decreases in PPV (from 14.17 +/- 10.57 to 12.66 +/- 9.64; p > 0.05), while we did observe significant decreases in PVI (from 21.91 +/- 13.99 to 20.46 +/- 14.12; p < 0.05). The PPV fluid responsiveness cut-off value in the SP and TP was 20% (78.95% sensitivity, 77.05% specificity) and 18% (76.67% sensitivity, 72.46% specificity), respectively. The PVI fluid responsiveness cut-off value in the SP and TP was 20% (80.49% sensitivity, 81.03% specificity) and 16% (81.25% sensitivity, 62.69% specificity), respectively. The area under the ROC of the PPV and PVI was 0.843 and 0.858 in the SP, respectively, and 0.760 and 0.747 in the TP, respectively. The PPV and PVI were correlated in the SP (r = 0.578; p = 0.001) and the TP (r = 0.517; p = 0.001). Conclusions. Our results showed that the PPV and PVI were correlated independent of position change in sepsis patients. Both tests appear to be equivalently reliable. However, the ability of the PPV and PVI to predict fluid responsiveness decreased in the TP in our study.en_US
dc.description.sponsorshipTrakya University Scientific Research Projects Unit [TUBAP 2014/13]en_US
dc.description.sponsorshipThe study funded by Trakya University Scientific Research Projects Unit numbered as TUBAP 2014/13.en_US
dc.identifier.doi10.22514/SV132.112017.14
dc.identifier.endpage96en_US
dc.identifier.issn1334-5605
dc.identifier.issn1845-206X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85037866250en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.22514/SV132.112017.14
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23443
dc.identifier.volume13en_US
dc.identifier.wosWOS:000418776800014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMre Pressen_US
dc.relation.ispartofSigna Vitaeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPulse Pressure Variationen_US
dc.subjectPleth Variability Indexen_US
dc.subjectFluid Responsivenessen_US
dc.subjectSepsisen_US
dc.subjectPredicts Fluid Responsivenessen_US
dc.subjectRespiratory Changesen_US
dc.subjectArterial-Pressureen_US
dc.subjectSepsisen_US
dc.subjectVolumeen_US
dc.titleComparing pulse pressure variation and pleth variability index in the semi-recumbent and trendelenburg position in critically ill septic patientsen_US
dc.typeArticleen_US

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