Evaluation of Pancreatic Malign Tumours with Mangafodipir Trisodium

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dc.authorwosidTosun, Alptekin/AAA-1350-2021
dc.contributor.authorArgimak, Yasin
dc.contributor.authorTemizoz, Osman
dc.contributor.authorTosun, Alptekin
dc.contributor.authorCakir, Bilge
dc.date.accessioned2024-06-12T11:08:08Z
dc.date.available2024-06-12T11:08:08Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: Our study aimed to assess the diagnostic capabilities of mangafodipir trisodium (Mn-DPDP)-enhanced magnetic resonance imaging for the evaluation of pancreatic malign mass. Patients and Methods: Magnetic resonance images of 17 patients (7 females, 10 males; mean age 63.2 +/- 12 years; range 36 to 80 years) suspected of pancreatic tumor by abdominal ultrasonography and computed tomography findings, were examined in terms of signal to noise (S/N) and contrast to noise (C/N) ratios before and after administration of Mn-DPDP using T1 A SE, Fat Sat T1 A SE and GRE T1 A sequences. Results: Before and after administration of Mn-DPDP, the increase in S/N ratios of normal pancreatic parenchyma were found as 22.81%, 32.88% and 20% in T1 A SE, Fat Sat T1 A SE and GRE T1 A sequences, respectively. The increase in C/N ratios obtained from signal intensity values of normal pancreatic tissue and tumor were found as 58.69%,125.41% and 62.06% in T1 A SE, Fat Sat T1 A SE and GRE T1 A sequences, respectively. Furthermore, in all sequences, before and after contrast medium administration, the increase of C/N ratios were found statistically significant (paired Student's t test, P<0.0001). Conclusion: The differences of C/N ratio using Mn-DPDP as a contrast agent may contribute to the diagnosis of pancreatic malign masses.en_US
dc.identifier.endpage58en_US
dc.identifier.issn1301-3149
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-70349094908en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22297
dc.identifier.volume26en_US
dc.identifier.wosWOS:000265174300009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherAves Yayincilik, Ibrahim Karaen_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMangafodipir Trisodium (Mn-DPDP)en_US
dc.subjectContrast-To-Noise Ratioen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectPancreasen_US
dc.subjectTumoren_US
dc.subjectHelical Cten_US
dc.subjectMn-Dpdpen_US
dc.subjectAdenocarcinomaen_US
dc.subjectEnhancementen_US
dc.subjectDiagnosisen_US
dc.subjectDiseaseen_US
dc.titleEvaluation of Pancreatic Malign Tumours with Mangafodipir Trisodiumen_US
dc.typeArticleen_US

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