Investigation of antimicrobial resistance and virulence genes of Campylobacter isolates from patients in a tertiary hospital in Edirne, Turkey

Basit Öğe Kaydı
dc.contributor.authorEryildiz, Canan
dc.contributor.authorTabakcioglu, Kiymet
dc.contributor.authorKuyucuklu, Gulcan
dc.contributor.authorSakru, Nermin
dc.date.accessioned2024-06-12T10:52:01Z
dc.date.available2024-06-12T10:52:01Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: Campylobacter is one of the most common pathogens that cause food-borne infections worldwide. The aim of this study was to determine the antimicrobial resistance rates and the presence of multiple virulence genes in Campylobacter isolates obtained from humans. Materials and Methods: In this study, 71 Campylobacter isolates obtained from human faecal samples were used. Antimicrobial susceptibility tests were performed through the gradient strip method. The presence of virulence genes was investigated by monoplex and multiplex polymerase chain reaction. Results: The rate of resistance of the 66 Campylobacter jejuni isolates was 12.1% for erythromycin, 40.9% for tetracycline and 68.2% for ciprofloxacin. Only one of five Campylobacter coli isolates was resistant to these three antimicrobial agents. The flaB, pldA, cdtA, cadF, cdtC and ceuE genes were found in all 66 of the C. jejuni isolates. In the C. jejuni isolates, positivity rates of 92.4% for flaA, 96.7% for cdtB, 98.5% for ciaB, 90.9% for dnaJ and 96.7% for racR were observed. The flaA, flaB, ciaB, cdtA and cdtC genes were present in all C. coli isolates. Conclusions: It was detected that there is an increase in antimicrobial resistance of Campylobacter strains in our region, and most of the isolates harbour virulence genes.en_US
dc.description.sponsorshipTrakya University Scientific Research Fund [TUBAP-2017/54]en_US
dc.description.sponsorshipThis study was financially supported by the Trakya University Scientific Research Fund (TUBAP-2017/54).en_US
dc.identifier.doi10.4103/ijmm.IJMM_20_78
dc.identifier.endpage161en_US
dc.identifier.issn0255-0857
dc.identifier.issn1998-3646
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85090319745en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage157en_US
dc.identifier.urihttps://doi.org/10.4103/ijmm.IJMM_20_78
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18568
dc.identifier.volume38en_US
dc.identifier.wosWOS:000569422500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofIndian Journal Of Medical Microbiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial Resistanceen_US
dc.subjectCampylobacteren_US
dc.subjectHumanen_US
dc.subjectVirulence Genesen_US
dc.subjectMultiplex Pcr Assayen_US
dc.subjectAntibiotic-Resistanceen_US
dc.subjectMolecular Characterizationen_US
dc.subjectJejunien_US
dc.subjectColien_US
dc.subjectIdentificationen_US
dc.subjectHumansen_US
dc.subjectInvasionen_US
dc.subjectMeaten_US
dc.titleInvestigation of antimicrobial resistance and virulence genes of Campylobacter isolates from patients in a tertiary hospital in Edirne, Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu