Pulmonary artery aneurysms in Behcet's syndrome: a review of the literature with emphasis on geographical differences
Küçük Resim Yok
Tarih
2015
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Clinical & Exper Rheumatology
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective. To investigate the frequency of Behcet's syndrome (BS) with pulmonary artery aneurysms (FAA) publications, the most lethal complication of BS, as reported from different countries and to provide a review of diagnostic techniques, treatment approaches and prognosis. Methods. Countries from each continent with a population of 4 million and over were chosen (n=128). A PubMed search for BS, FAA and the country name was conducted and 23 countries with BS and FAA were identified. The, full, texts of articles (n=91) were analysed for data including gender, age, accompanying Vascular findings, diagnostic techniques, treatment modalities and mortality rates. Results. A total of 207 (183 males, 24 females) patients with BS and FAA were reported in 91 articles originating from 23 countries. As expected there was a significant correlation (r=0.88, p<0.001) between the total number of articles about BS (n=4431) and those related to FAA and BS. In a simple linear regression analysis the number of BS and FAA articles from Japan was significantly below the identity line while in Turkey there was a propensity to publish more articles related to FAA than expected. One hundred and sixteen patients (56%) were treated with immunosuppressive therapy. Biologics were used only in 5 patients (2%). Of the 207 patients, 62 (30%) died. Conclusion. FAA is mostly reported as case reports from countries where BS is common. FAA might be uncommon in Japan. The prognosis of FAA could be getting better.
Açıklama
Anahtar Kelimeler
Behcet's Syndrome, Pulmonary Artery Aneurysms, Vascular Involvement, Disease, Manifestations, Severity
Kaynak
Clinical And Experimental Rheumatology
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
33
Sayı
6
