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Öğe Intrauterine instillation of trichloroacetic acid is effective for the treatment of dysfunctional uterine bleeding(Elsevier Science Inc, 2005) Kucuk, M; Okman, TKObjective: To evaluate the effectiveness of trichloroacetic acid (TCA) instillation into uterine cavity for the treatment of dysfunctional uterine bleeding (DUB). Design: Prospective clinical study. Setting: A university research hospital. Patient(s): Ninety women participated who had dysfunctional uterine bleeding. Intervention(s): Ninety-five percent of TCA was instilled in to uterine cavity for endometrial ablation in women with dysfunctional uterine bleeding who want conservative treatment. Participants in group 1 received only TCA; participants in group 2 received a single dose of gonadotropin-releasing hormone analogue 1 month before the procedure. Main Outcome Measure(s): All participants underwent an evaluation that included cycle history, body mass index measurement, and transvaginal ultrasonography of pelvis, diagnostic hysteroscopy and endometrial biopsy. Result(s): At the end of 12 months of the treatment, amenorrhea rates in group 1 and group 2 were 26.7% vs. 31.1%, with pooled amenorrhea, hypomenorrhea, and eumenorrhea rate of 95.6% vs. 97.8%, respectively. There was no significant differences between the groups vis-a-vis postprocedure results. More than 90% of women who have this procedure are satisfied with the results. There were no observed negative effects or related complications with this treatment. Conclusion(s): An instillation of TCA into uterine cavity produces acceptable results and provides conservative management of DUB. (C)2005 by American Society for Reproductive Medicine.Öğe Non-closure of visceral peritoneum at abdominal hysterectomy(Elsevier Sci Ireland Ltd, 2001) Kucuk, M; Okman, TKOur purpose was to determine whether non-closure of the visceral peritoneum alters post-operative outcome at abdominal hysterectomy. A prospective, randomized trial was performed. Of the 100 evaluable subjects, 50 had the visceral peritoneum left open whereas 50 were closed. Patients were observed for evidence of morbidity after the operation. Analysis of data was performed with use of the unpaired t-test for continuous variables. The visceral peritonization process at abdominal hysterectomy does not provide immediate post-operative benefits while unnecessarily lengthening surgical time and anesthesia exposure. We suggest that visceral peritonization process can be abolished at abdominal hysterectomy. (C) 2001 International Federation of Gynecology and Obstetrics. All rights reserved.