Yazar "Ebik, Mustafa" seçeneğine göre listele
Listeleniyor 1 - 7 / 7
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Double Coronary-Cameral Fistula Draining to the Right Ventricle in a Patient with Mitral Stenosis: is it Clinically Relevant?(Galenos Publ House, 2023) Ebik, Mustafa; Ozturk, Cihan; Ustabasioglu, Fethi Emre[Abstract Not Available]Öğe The Effect of Thyroid Stimulating Hormone Level Within the Reference Range on In-Hospital and Short-Term Prognosis in Acute Coronary Syndrome Patients(Mdpi, 2019) Gurdogan, Muhammet; Altay, Servet; Korkmaz, Selcuk; Kaya, Caglar; Zeybey, Utku; Ebik, Mustafa; Demir, MelikBackground and objectives: Despite being within the normal reference range, changes in thyroid stimulating hormone (TSH) levels have negative effects on the cardiovascular system. The majority of patients admitted to hospital with acute coronary syndrome (ACS) are euthyroid. The aim of this study was to investigate the effect of TSH level on the prognosis of in-hospital and follow-up periods of euthyroid ACS patients. Materials and Methods: A total of 629 patients with acute coronary syndrome without thyroid dysfunction were included in the study. TSH levels of patients were 0.3-5.33 uIU/mL. Patients were divided into three TSH tertiles: TSH level between (1) 0.3 uIU/mL and <0.90 uIU/mL (n = 209), (2) 0.90 uIU/mL and <1.60 uIU/mL (n = 210), and (3) 1.60 uIU/mL and 5.33 uIU/mL (n = 210). Demographic, clinical laboratory, and angiographic characteristics were compared between groups in terms of in-hospital and follow-up prognosis. Results: Mean age was 63.42 +/- 12.5, and 73.9% were male. There was significant difference between tertiles in terms of TSH level at admission (p < 0.001), the severity of coronary artery disease (p = 0.024), in-hospital mortality (p < 0.001), in-hospital major hemorrhage (p = 0.005), total adverse clinical event (p = 0.03), follow-up mortality (p = 0.022), and total mortality (p < 0.001). In multivariate logistic regression analysis, the high-normal TSH tertile was found to be cumulative mortality increasing factor (OR = 6.307, 95%; CI: 1.769-22.480; p = 0.005) during the 6-month follow-up period after hospitalization and discharge. Conclusions: High-normal TSH tertile during hospital admission in euthyroid ACS patients is an independent predictor of total mortality during the 6-month follow-up period after hospitalization and discharge.Öğe THE ETIOLOGY AND AGE-RELATED PROPERTIES OF PATIENTS WITH DELIRIUM IN CORONARY INTENSIVE CARE UNIT AND ITS EFFECTS ON INHOSPITAL AND FOLLOW UP PROGNOSIS(Literatura Medica, 2020) Altay, Servet; Gurdogan, Muhammet; Kaya, Caglar; Kardas, Fatih; Zeybey, Utku; Cakir, Burcu; Ebik, MustafaObjective - Delirium is a syndrome frequently encountered in intensive care and associated with a poor prognosis. Intensive care delirium is mostly based on general and palliative intensive care data in the literature. In this study, we aimed to investigate the incidence of delirium in coronary intensive care unit (CICU), related factors, its relationship with inhospital and follow up prognosis, incidence of age-related delirium and its effect on outcomes. Methods - This study was conducted with patients hospitalized in CICU of a tertiary university hospital between 01 August 2017 and 01 August 2018. Files of all patients were examined in details, and demographic, clinic and laboratory parameters were recorded. Patients confirmed with psychiatry consultation were included in the groups of patients who developed delirium. Patients were divided into groups with and without delirium developed, and baseline features, inhospital and follow up prognoses were investigated. In addition, patients were divided into four groups as <65 years old, 65-75 yo, 75-84 yo and> 85 yo, and the incidence of delirium, related factors and prognoses were compared among these groups. Results - A total of 1108 patients (mean age: 64.4 +/- 13.9 years; 66% men) who were followed in the intensive care unit with variable indications were included in the study. Of all patients 11.1% developed delirium in the CICU. Patients who developed delirium were older, comorbidities were more frequent, and these patients showed increased inflammation findings, and significant increase in inhospital mortality compared to those who did not develop delirium (p<0.05). At median 9-month follow up period, rehospitalization, reinfarction, cognitive dysfunction, initiation of psychiatric therapy and mortality were significantly higher in the delirium group (p<0.05). When patients who developed delirium were divided into four groups by age and analyzed, incidence of delirium and mortality rate in delirium group were significantly increased by age (p<0.05). Conclusion - Development of delirium in coronary intensive care unit is associated with increased inhospital and follow up morbidity and mortality. Delirium is more commonly seen in geriatric patients and those with comorbidity, and is associated with a poorer prognosis. High-risk patients should be more carefully monitored for the risk of delirium.Öğe Giant Saccular Aneurysm of the Right Coronary Artery(H M P Communications, 2021) Ozturk, Cihan; Ebik, Mustafa[Abstract Not Available]Öğe The importance of speckle tracking echocardiography in the evaluation of cardiac functions in patients with rheumatoid arthritis(Turkish League Against Rheumatism, 2024) Ebik, Muserref; Tastekin, Nurettin; Gurdogan, Muhammet; Ebik, Mustafa; Birtane, Murat; Emmungil, Hakan; Yilmazer, BarisObjectives: In this study, we aimed to analyze the layer-specific strain values obtained by speckle tracking echocardiography (STE) method in the determination of subclinical cardiac dysfunction in rheumatoid arthritis (RA) patients. Patients and methods: Between February 2019 and October 2019, a total of 63 female RA patients (mean age: 51.82 +/- 6.07 years; range, 40 and 65 years) who had a confirmed diagnosis were included. Thirty-one age-matched female healthy individuals (mean age: 50.71 +/- 5.37 years; range, 40 and 65 years) were selected as the control group. The patients were divided into three groups according to the duration of disease as <5 years, 5-10 years and >10 years. The Disease Activity Score in 28 joint - C-reactive protein (CRP) was used to determine disease activation. The standard assessment included complete serum CRP, anti-cyclic citrullinated peptide, rheumatoid factor, N-terminal pro B-type natriuretic peptide (NT-proBNP), and homocysteine. Global longitudinal strain (GLS) analysis was performed with STE. Results: The NT-proBNP values were found to be higher in RA patients compared to the control group (p=0.044). In terms of conventional echocardiographic parameters, a significant difference between E/A and E/E' ratios was observed (p<0.001 and p=0.015). Endocardium, transmural, and epicardium GLS values obtained by STE were found to be lower in RA patients (p<0.05). The left ventricular (LV) GLS values worsened, as the duration of disease increased (p<0.05). There was a significant correlation between RA disease activity and LV GLS values, showing that increasing levels of disease activity was associated with worse LV GLS (r=0.583, p<0.01 and r=0.681, p<0.01 and r=0.689, p<0.01 for endocardium, transmural and epicardium, respectively). Conclusion: Our study results suggest that the layer-specific GLS values obtained by STE decrease in RA patients.Öğe Primer perkütan koroner girişim uygulanan st-segment elevasyonlu miyokard infarktüsü tanılı 80 yaş üstü hastaların bir yıllık takip sonuçları(Trakya Üniversitesi, 2023) Ebik, Mustafa; Gürdoğan, MuhammetDünyada yaşlı nüfusunun artmasıyla orantılı olarak klinik pratikte karşılaşılan ST-segment elevasyonlu miyokard infarktüs (STEMİ) tanılı yaşlı ve çok yaşlı hastaların sıklığı da artış göstermektedir. STEMİ hastaları için tüm yaş gruplarında öncelikli tercih edilen reperfüzyon stratejisi primer perkütan koroner girişim olmasına rağmen klinik çalışmalarda 80 yaş ve üstü kırılgan hastaların yeterli oranda temsil edilmediği görülmektedir. Bu çalışmada STEMİ tanısıyla hastaneye kabul edilen ve primer perkütan koroner girişim uygulanan ?80 yaş hastaların hastane içi ve bir yıllık takip dönemindeki klinik izlem sonuçlarını, kardiyak istenmeyen olay gelişimi ile ilişkili faktörleri araştırmayı ve bu sonuçların 80 yaş altı hastaların verileriyle karşılaştırmayı amaçladık. Toplamda 449 STEMİ hastası çalışmaya dahil edildi. Hastalar 80 yaş ve üzeri ve 80 yaş altı olarak iki alt gruba ayrıldı. 80 yaşın altındakilerin sayısı 350, 80 yaş ve üzerinde olanların sayısı ise 99'du. Bu iki grubun, klinik özellikleri, kardiyovasküler risk faktörleri, hastane içi komplikasyonlar ve olayları, perkütan koroner girişim özellikleri ve 1 yıllık sonuçları karşılaştırıldı. Ayrıca 80 yaş ve üzeri hastalarda, hastane içi mortalite, 1 yıllık mortalite ve 1 yıl içinde gelişen tekrarlayan kardiyak olayları predikte eden faktörler araştırıldı. Yaşlı hastaların genç hastalara göre, kardiyovasküler risk faktörleri ve komorbit hastalıklarının daha fazla olduğu bulundu (hipertansiyon p<0,001, atriyal fibrilasyon p:0,001, kronik böbrek yetmezliği p:0,031). Yaşlı hastaların ağrı başlangıç saati ve kapı-balon süresinin uzun olması nedeniyle total iskemik süresinin genç hastalara göre daha yüksek olduğu saptandı (ağrı başlangıcı p:0,040, kapı-balon zamanı p:0,066). Yaşlı hastaların hastane içi mortalitesi %31,3, 1 yıllık mortalitesi ise %20,6 olarak bulundu ve genç hastalara göre daha yüksek olduğu görüldü (hastane içi mortalite p<0,001, 1 yıllık mortalite p<0,001). 80 yaş ve üzeri hastalarda hastane içi mortaliteyi predikte eden faktörler, Killip?2 akut kalp yetmezliği ile başvuru [OR (%95 GA): 27,23 ( 3,42-216,66), p:0,002 ], VT-VF gelişmesi [OR (%95 GA): 20,35 ( 3,12-132,82), p:0,002], akut böbrek yetmezliği gelişmesi [OR (%95 GA): 8,12 ( 1,53- 42,94 ), p:0,014 ] ve koroner no-reflow/yavaş akım gelişmesi [OR (%95 GA): 14,56 ( 1,61-131,09 ), p:0,017] olarak bulundu. 80 yaş ve üzeri hastalarda 1 yıl içindeki mortaliteyi predikte eden faktörler, kapı balon zamanının uzun olması [ OR (%95 GA): 1,04 ( 1,01-1,07 ) p:0,003 ] ve ACEİ/ARB grubu ilaçları kullanmamak [ OR (%95 GA): 0,23 ( 0,52-1,09 ), p:0,065 ] olarak bulundu. 80 yaş ve üzeri hastalarda 1 yıl içinde tekrarlayan olay gelişimini predikte eden faktörler, kapı-balon zamanının uzun olması [ OR (%95 GA): 1,04 ( 1,01-1,07 ), p:0,007 ], yüksek E/E' [OR (%95 GA): 1,80 ( 1,07-3,02 ), p:0,026 ] ve kısa DAPT süresi [ OR (%95 GA): 0,85 ( 0,74-0,98 ), p:0,033 ] olarak bulundu. Sonuç olarak, 80 yaş ve üzeri STEMİ tanılı kırılgan hasta popülasyonunda hem hastane içi mortalite, hem de 1 yıllık takip döneminde mortalite ve istenmeyen kardiyak olay sıklığı, 80 yaş altındaki hastalar ile karşılaşırıldığında anlamlı derecede yüksek saptanmıştır. Anahtar kelimler: 80 yaş, STEMİ, perkütan koroner girişim, mortalite, 1 yıllık takip, prediktör faktörler.Öğe Risk of premature coronary atherosclerosis in patients with nonalcoholic fatty liver disease(Assoc Medica Brasileira, 2022) Taylan, Gokay; Ebik, Mustafa; Solak, Serdar; Kaya, Caglar; Yalta, KenanOBJECTIVE: In the current literature, there are few studies investigating the relationship between premature coronary atherosclerosis and nonalcoholic fatty liver disease. We aimed to evaluate the relationship between nonalcoholic fatty liver disease and premature coronary atherosclerosis. METHODS: In this cross-sectional study, female patients aged <55 years and male patients aged <50 years were enrolled. Both male and female patients underwent coronary angiography and abdomen ultrasonography between 2014 and 2019. A stepwise binary logistic regression analysis was carried out to evaluate the independent variables related to premature coronary atherosclerosis and nonalcoholic fatty liver disease. A p-value<0.05 was considered statistically significant. RESULTS: nonalcoholic fatty liver disease was present in 44% of patients (n=377). Notably, 62% of the patients were female and the mean age was 44.5 (39-49) years. In a multivariate analysis, nonalcoholic fatty liver disease was shown to be an independent risk factor of premature coronary atherosclerosis (OR 1.438; 95%CI, 1.050-1.969; p=0.024). CONCLUSIONS: The presence of nonalcoholic fatty liver disease is an important independent risk factor for the development of premature coronary atherosclerosis.