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Öğe Complications of misuse of Bacillus Calmette-Guerin(Comenius Univ, 2011) Cevik, Y.; Ozer, M.; Das, M.; Ertok, I; Kavalci, C.; Ergul, E.; Durukan, P.Intravesical BCG is a good treatment choice for vesical carcinomas. Nevertheless, it can also become a mortal toxin when applied in a wrong way. The application routes of the prescribed drug should be rigorously described to patients and detailed instructions regarding the ways of application such as intravesical application should be given to the persons taking this medicine (Ref. 9). Full Text in free PDF www.bmj.sk.Öğe Poisoning from wild mushroom in the Trakya region: an analysis of seven years(Sage Publications Ltd, 2010) Kavalci, C.; Kavalci, G.; Guzel, A.; Inal, M.; Durukan, P.; Karasalihoglu, S.; Cevik, Y.Introduction: Mushroom poisoning is a medical emergency, diagnostic and treatment dilemma for physicians. Most cases present with self-limiting gastrointestinal symptoms. The regional profile of poisoning epidemiology in Turkey has previously been reported. However, information about mushrooms is still limited. The aim of this study was to identify the epidemiology of wild mushroom poisonings in the Trakya region in a 7-year period. Materials and methods:The study was designed retrospectively by examining the files of the patients who presented to the emergency department of Trakya University Faculty of Medicine from January 2002 to July 2008. Results: The overall male to female ratio was 0.88:1. All patients were intoxicated due to accidental pick up and consumption of wild mushrooms from open fields, woodlands and meadows. The most common findings on physical examination were epigastric pain. Fifty-six patients (74.7%) were discharged from the emergency department, 18 patients (24.0%) were hospitalized (one died on the 5th day), and one patient died in the emergency department. Conclusions: Care should be taken especially for patients presenting late. Patients may have hepatic dysfunction that needs haemodialysis or even liver transplantation. (Hong Kong j.emerg.med. 2010;17:341-346)Öğe The relationship among plasma copeptin, carboxyhemoglobin, and lactate levels in carbon monoxide poisoning(Sage Publications Ltd, 2020) Ozkan, S.; Salt, O.; Durukan, P.; Sen, A.; Bulbul, E.; Duman, A.; Kavalci, C.Objective: The aim of our study is to determine whether there is a change in the plasma levels of copeptin and there is a relationship among the plasma levels of carboxyhemoglobin (COHb), lactate, and copeptin levels in patients presenting to the emergency department with carbon monoxide (CO) poisoning. Methods: Fifty-seven patients admitted to the emergency department with CO poisoning were included in the study. The blood samples of the patients were collected on arrival 0th, 6th, and 12th hours for copeptin, lactate, and COHb levels. Data were analyzed using SPSS-17 statistical software. Results: Arrival serum copeptin levels of the patients were compared to copeptin levels of healthy individuals and a statistically significant difference was found between them (p = 0.008). There was a statistically significant difference between the arrival levels of copeptin and 6th-hour (p = 0.006) and 12th-hour (p = 0.001) levels of copeptin. There was no significant difference between 6th-hour and 12th-hour copeptin levels (p = 0.51). In terms of serum lactate levels, there was a significant difference between arrival and 6th h (p < 0.001), arrival and 12th h (p < 0.001), and 6th and 12th h (p < 0.001). Likewise, in terms of serum COHb levels, there was a significant difference between arrival and 6th h (p < 0.001), arrival and 12th h (p < 0.001), and 6th and 12th h (p < 0.001). There was a positive correlation between COHb and lactate levels on arrival (r = 0.52; p = 0.001). Conclusion: Copeptin as a stress hormone can be used in the diagnosis and monitoring of patients with CO poisoning. However, the copeptin level was not superior to COHb and lactate levels.Öğe Value of biomarker-based diagnostic test in differential diagnosis of hemorrhagic-ischemic stroke(Comenius Univ, 2011) Kavalci, C.; Genchallac, H.; Durukan, P.; Cevik, Y.Background and aim: Stroke is an emergency which threatens life and the third leading cause of death in developed countries and the leading cause of long-term disability. By means of this study, it was aimed to evaluate the position of triage stroke panel in differential diagnosis of acute hemorrhagic stroke and ischemic stroke and sub-types of ischemic stroke. Material and methods: Patients with acute stroke admitted to Emergency Department were prospectively recruited between June 2008-January 2009. BNP, D-dimer, MMP-9, S-100b levels were asseyed. Statistical significance for intergroup differences was assessed by Pearson's X-2 for categorical variables and Mann-Whitney U test or Kruskal-Wallis test for continuous variables. Results and conlusion: A total of 100 consecutive patients with a diagnosis of stroke were evaluated. Of these, 29 (29 %) patients had brain hemorrhages on the computed tomography scan performed the Emergency Department, 71 (71 %) patients had ischemic stroke. It was observed that the intercept obtained as a result of jointly evaluating BNP, D-dimer, MMP9 and S100b is more important in differential diagnosis (p<0.005). We suggest that using a combination of plasma biomarkers may be usefull to ischemic or hemorrhagic stroke for differential diagnosis (Tab. 4, Ref. 22). Full Text in free PDF www.bmj.sk.