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Öğe Bazı kimyasal madde uygulamalarının ıspanakların soğuğa dayanıklılığına etkisi üzerinde araştırmalar(Trakya Üniversitesi, 1999) Deveci, Murat; Şalk, AhmetIV ÖZET DOKTORA TEZİ BAZI KİMYASAL MADDE UYGULAMALARININ ISPANAKLARIN SOĞUĞA DAYANIKLILIĞINA ETKİSİ ÜZERİNDE ARAŞTIRMALAR Hazırlayan: Murat DEVECİ TRAKYA ÜNİVERSİTESİ TEKİRDAĞ ZİRAAT FAKÜLTESİ BAHÇE BİTKİLERİ BÖLÜMÜ Araştırma Görevlisi TRAKYA ÜNİVERSİTESİ FEN BİLİMLERİ ENSTİTÜSÜ BAHÇE BİTKİLERİ ANA BİLİM DALI DANIŞMAN: Prof. Dr. Ahmet ŞALK 1999, sayfa: 253 Jüri: Prof. Dr. Ahmet ŞALK Prof. Dr. Ercan ÖZZAMBAK Doç.Dr. Levent ARIN Bu araştırma, Yalova Atatürk Bahçe Kültürleri Merkez Araştırma Enstitüsü ve Trakya Üniversitesi Tekirdağ Ziraat Fakültesi sera ve labaratuvar imkanları kullanılarak 1996-1998 yıllan arasında Ispanak çeşitlerinin dona dayanımlarının belirlenmesi ve bu dayanıklılığı yapraklara püskürtülen kimyasal madde uygulamaları ile arttırılması ve ayrıca düşük sıcaklık şartlan sonrası, çeşitlerin bitki besin maddeleri ile aralanndaki ilişkilerin incelenmesi amacıyla kurulmuştur. Denemede faktör olarak iki çeşit (Matador ve Spinoza), dört farklı gelişme dönemi (kotiledon, iki ve altı gerçek yapraklı dönemler ile hasat olgunluğu dönemi), üç farklı düşük sıcaklık (-4, -8 ve -12°C) ve kimyasal muamele (kontrol, glikoz, sakkaroz, CaCb ve NaCl ) kullanılmıştır. Deneme tesadüf bloklarında bölünmüş parseller deneme desenine göre 3 tekerrürlü olarak kurulmuş, her çeşit kendi içindeV değerlendirilmiş ve her dönemde 5 parsel, tüm yetiştirme dönemlerinde 120 parsel ve her parselde 10 bitki kullanılmıştır. Bitkinin değişik vegetatif dönemlerinde; canlılık oranı, elektriki iletkenlik, zar geçirgenliği testleri ile klorofil a, b ve toplam klorofil miktarları, toplam azot, toplam protein, fosfor, potasyum, sodyum, kalsiyum, demir, bakır, çinko ve mangan içerikleri saptanmıştır. Ayrıca ele alman tüm kriterler arasındaki ikili ilişkiler belirlenmiştir. Denemede materyal olarak kullandığımız Matador ve Spinoza çeşitleri arasında; Spinoza çeşidi Matador çeşidine nazaran soğuğa daha dayanıklı olduğu -8°C'ye kadar kimyasal muamele yapılmadan dayanabildiği anlaşılmıştır. Ayrıca yapılan kimyasal madde uygulamalarında Matador'da glikoz, Spinoza'da sakkaroz ve NaCl'ün bitkilerin dona daj^anıklılıklarım arttırdığı belirlenirken, CaCb'un ise dayanıklılıkta olumsuz etki yaptığı tespit edilmiştir. Soğuk testleri sonrasında bitkilerde besin maddeleri arasında değişimler incelenmiş ve çeşitlerin canlılık oranı ile toplam azot, toplam protein, potasyum, sodyum, demir, çinko, mangan ve klorofil içerikleri arasında olumlu önemli ilişkiler belirlenmiş, ancak canlılık oranı ile elektriki iletkenlik ve zar geçirgenlikleri arasında negatif yönde önemli ilşkiler saptanmıştır.Öğe Comprehensive Genetic Analysis of RASopathy in the Era of Next-Generation Sequencing and Definition of a Novel Likely Pathogenic KRAS Variation(Karger, 2022) Demir, Selma; Kostek, Huemeyra Yasar; Sanri, Aslihan; Yildirim, Ruken; Comlek, Fatma Oezguec; Yalcintepe, Sinem; Deveci, MuratIntroduction: Germline pathogenic variations of the genes encoding the components of the Ras-MAPK pathway are found to be responsible for RASopathies, a clinically and genetically heterogeneous group of diseases. In this study, we aimed to present the results of patients genetically investigated for RASopathy-related mutations in our Genetic Diagnosis Center. Methods: The results of 51 unrelated probands with RASopathy and 4 affected relatives (31 male, 24 female; mean age: 9.327 +/- 8.214) were included in this study. Mutation screening was performed on DNA samples from peripheral blood of the patients either by Sanger sequencing of PTPN11 hotspot regions (10/51 probands), or by a targeted amplicon next-generation sequencing panel (41/51 probands) covering the exonic regions of BRAF, CBL, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, NF1, NRAS, PTPN11, RAF1, RASA2, RIT1, SHOC2, SOS1, SOS2, SPRED1, and KAT6B genes. Results: Pathogenic/likely pathogenic variations found in 22 out of 51 probands (43.13%) and their 4 affected family members were located in PTPN11, BRAF, KRAS, NF1, RAF1, SOS1, and SHOC2 genes. The c.148A>C (p.Thr50Pro) variation in the KRAS gene was a novel variant detected in a sibling in our patient cohort. We found supportive evidence for the pathogenicity of the NF1 gene c.5606G>T (p.Gly1869Val) variation which we defined in an affected boy who inherited the mutation from his affected father. Conclusion: Although PTPN11 is the most frequently mutated gene in our patient cohort, as in most previous reports, different mutation distribution among the other genes studied motivates the use of a next-generation sequencing gene panel including the possible responsible genes.Öğe Crop water stress index for assessing irrigation scheduling of drip irrigated broccoli (Brassica oleracea L var italica)(Elsevier, 2010) Erdem, Yesim; Arin, Levent; Erdem, Tolga; Polat, Serdar; Deveci, Murat; Okursoy, Hakan; Gultas, Huseyin T.This study was conducted to determine the possibility of a crop water stress index (CWSI) to schedule irrigation for broccoli (Brassica oleracea L var italica) grown with drip irrigation during the spring and autumn cultivation periods of 2007 The effects of five irrigation levels which were applied based on a ratio of Class A pan evaporation (k(cp) =0 050 075 1 00 and 1 25) with 7 days Interval on broccoli yields and resulting CWSI were investigated The highest yield and water use was obtained in the treatment of applied 50% of the evaporation measured in Class A pan for two seasons while the effects of irrigation programs on yield was not statistically significant The seasonal evapotranspiration in the treatments varied from 187 to 326 mm during the spring period and from 242 to 346 mm during the autumn period The CWSI was calculated using the empirical approach from measurements of Infrared canopy temperatures ambient air temperatures and vapor pressure deficit values for five irrigation levels An average threshold CWSI value of about 051 before irrigation produced the maximum yield The yield was directly correlated with mean CWSI values and the linear equation Y= -36 51(CWSI)2 +32 958(CWSI) + 0 772 with a determination coefficient R-2 = 099 and standard deviation S-yx =1 38 Mg ha(-1) can be used for yield prediction The soil water content soil matric potential above ground biomass and leaf area Index values were also found to correlate better with CWSI as a key function for modeling the crop growth model The CWSI value was useful for evaluating crop water stress in broccoli and should be useful for timing irrigation and predicting yield (c) 2010 Elsevier BV All rights reservedÖğe EVALUATION OF CARDIAC AUTONOMIC DYSFUNCTION AND THE RISK OF ARRHYTHMIA IN CHILDREN WITH MITRAL VALVE PROLAPSE(2023) Bindal, Abdullah; Deveci, MuratObjective: The occurrence of symptoms in patients with mitral valve prolapse (MVP) is linked to autonomic dysfunction and neuroendocrine causes rather than progressive mitral valve insufficiency. The goal was to assess the risk of autonomic dysfunction and arrhythmia in patients with MVP. Methods: A cohort of 63 individuals with MVP was compared to a control group of 64 age- and gender-matched children. A comprehensive assessment was conducted, comprising physical examination, medical history taking, and various diagnostic tests, including 12-lead electrocardiography, autonomic function testing, echocardiography, and 24-hour Holter rhythm monitoring. Results: In comparison to the control group, the MVP group had higher QTc dispersion, frontal QRS-T angle, Tp-e interval, and Tp-e/QTc ratio at rest. However, conventional measurements of heart rate variability in the Holter ECG or HRDC, a novel and understudied parameter in children, did not significantly differ between the two groups. Conclusion: Although cases with pathological findings in the initial ECG were excluded from our study, the widened frontal QRS-T angle seen in MVP patients is a novel finding, and that when compared to the control group, these patients' HRDC doesn't seem to differ noticeably.Öğe From cyanosis to diagnosis: A case report on right atrial fibroma in a pediatric patient(Wiley, 2023) Sengul, Fatma Sevinc; Yildiz, Okan; Deveci, Murat; Ayyildiz, Pelin; Guzeltas, AlperA 3-year-old female patient presented with symptoms of cyanosis and intermittent eyelid edema, leading to the discovery of a lobulated mass in the right atrium, obstructing the superior vena cava. Despite the inability to entirely remove the mass due to its origins in the right atrium myocardium and its extension towards the sinoatrial node, successful surgical intervention and subsequent histopathological evaluation identified the mass as a fibroma, and postoperative symptoms were significantly alleviated.Öğe Investigations on Yield and Quality of Kohlrabi (Brassica Oleraceae Var. Gongylodes L.) in the Trakya Region of Turkey(Trakya Üniversitesi, 2003) Arın, Levent; Salk, Ahmet; Deveci, Murat; Polat, SerdarBu araştırma 2000 yılı ilkbahar ve sonbahar döneminde Trakya koşullarında alabaş (Brassica oleraceae var. gongylodes L.) yetiştirme olanağını belirlemek amacıyla yürütülmüştür. Her bir periyolla üç alabaş çeşidi (Express Forcer, Neckar, Lahn), iki fide yaşı (dört ve altı haftalık) ve üç dikim zamanı (iki hafta aralıklarla ve ilkbaharda Nisan ve Mayısta, sonbaharda Eylül ve Ekimde) verim ve kalite özellikleri bakımından değerlendirilmiştir. Neckar ve Express Forcer çeşitleri her iki sezonda da Lahn'dan daha yüksek verim ve kalite vermiştir. Sonbalıarda dört haftalık süre fide yetiştirme süresi yeterliyken, ilkbalıarda altı haftalık fidelerden daha yüksek verim elde edilmiştir.Öğe Is there myocardial involvement in children with long-term follow- up for Kawasaki disease? A study based on two-dimensional speckle tracking echocardiography(Aves, 2021) Kayabey, Ozlem; Tuncer, Tunc; Deveci, Murat; Basar, Evic Zeynep; Babaoglu, KadirObjective: This study aimed to determine the possibility of subclinical myocardial dysfunction detected by strain echocardiography in the late period of children with Kawasaki disease. Material and Methods: The study enrolled 30 patients with Kawasaki disease with a follow-up period of at least 12 months and 30 healthy age- and gender-matched children. During the follow-up period, standard echocardiography, pulsed and tissue Doppler, and strain echocardiography were recorded for both groups. Results: The mean age at the time of the diagnosis was 2.6 +/- 2.3 years (2 months-11 years). The mean follow-up period after the diagnosis was 3.55 +/- 2.20 years. Conventional echocardiography, M mode, pulsed and tissue Doppler values, and myocard performance index did not reveal significant differences. Left ventricle strain and strain rate parameters obtained by apical four-, three-, and two-chamber views did not show statistical differences between patients and controls. There was a positive correlation between the duration of follow-up and global fourand three-chamber longitudinal strain and global longitudinal strain values (r=0.465, p=0.010; r=0.414, p=0.023; r=0.492, p=0.006, respectively), whereas global radial strain showed negative correlation (r=-0.517, p=0.003). Conclusion: The analysis of systolic strain and strain rate did not detect a subclinical myocardial dysfunction in the long-term follow-up of Kawasaki disease. However, strain values showed variability with the follow-up periods, which indicates that Kawasaki disease might cause left ventricular dysfunction in the later phases. Therefore, a follow-up of children with a diagnosis of Kawasaki disease is of capital importance.Öğe Short Versus Long Head-up Tilt Test Protocols to Evaluate Vasovagal Syncope in Children(2022) Deveci, Murat; Kayabey, Özlem; Başar, Eviç Zeynep; Babaoğlu, AbdulkadirObjective: Vasovagal syncope is a common clinical problem in children and adolescents, for which the head-up tilt test (HUTT) is the standard diagnostic procedure. In this study, we evaluated sublingual nitroglycerine-stimulated HUTT protocols, comparing the results with passive phases of 20 minutes versus 45 minutes. Method: A total of 293 patients aged 6 to 18 years with a history of recurrent syncope were studied. Physical examination, laboratory parameters, and echocardiographic examination were normal in all. The patients underwent standard HUTT with sublingual nitroglycerin used in the active phase. A short protocol was used for one group (n=143) with a passive phase of 20 minutes, while testing in the others (n=150) comprised a long protocol, with a passive phase of 45 minutes. Results: There were no significant differences between the two groups in terms of age, sex, and length of time between the first syncope and the tilt test. In the short protocol group, HUTT results were positive in 43(30.1%) in the passive phase, 40(28%) in the active phase, and 83(58%) overall, compared with 65(43.3 %), 32(21.3%), and 97(64.7%), respectively, in the long protocol group. Among those in the long protocol group, 26 of 32 (81.5%) who had a positive response in the passive phase developed syncope within the first 20 minutes. Conclusion: The HUTT protocol with a short passive phase has the advantage of saving time while providing results comparable with the long protocol, which might be preferable in children and adolescents.Öğe Two Novel Pathogenic FBN1 Variations and Their Phenotypic Relationship of Marfan Syndrome(Thieme Medical Publ Inc, 2020) Yalcintepe, Sinem; Demir, Selma; Atli, Emine Ikbal; Deveci, Murat; Atli, Engin; Gurkan, HakanMarfan syndrome is an autosomal dominant disease affecting connective tissue involving the ocular, skeletal systems with a prevalence of 1/5,000 to 1/10,000 cases. Especially cardiovascular system disorders (aortic root dilatation and enlargement of the pulmonary artery) may be life-threatening. We report here the genetic analysis results of three unrelated cases clinically diagnosed as Marfan syndrome. Deoxyribonucleic acid (DNA) was isolated from EDTA (ethylenediaminetetraacetic acid)-blood samples of the patients. A next-generation sequencing panel containing 15 genes including FBN1 was used to determine the underlying pathogenic variants of Marfan syndrome. Three different variations, NM_000138.4( FBN1 ):c.229G>A(p.Gly77Arg), NM_000138.4( FBN1 ):c.165-2A>G (novel), NM_000138.4( FBN1 ):c.399delC (p.Cys134ValfsTer8) (novel) were determined in our three cases referred with a prediagnosis of Marfan syndrome. Our study has confirmed the utility of molecular testing in Marfan syndrome to support clinical diagnosis. With an accurate diagnosis and genetic counseling for prognosis of patients and family testing, the prenatal diagnosis will be possible.