Yazar "Aynaci, Ozer" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • Küçük Resim Yok
    Öğe
    A Case of Uncorrected Tetralogy of Fallot Presenting with Acute Ischemic Stroke
    (Aves, 2014) Tekatas, Aslan; Kehaya, Sezgin; Cagli, Bekir; Akdemir, Vedat; Aynaci, Ozer; Dogru, Yuce; Aksu, Feyza
    Tetralogy of Fallot (FT) is the most common cyanotic congenital heart disease. FT is mainly composed of ventricular septal defect, right ventricular outflow tract obstruction, pulmonary stenosis and right ventricular hypertrophy, but also can include dextrapositioned aorta (overriding aorta), additional malformations such as atrial septal defect, and coronary artery anomalies. In the first week of life patients undergo palliative anastamosis between a pulmonary artery and subclavian artery and after they become eligible for major surgery total correction isperformed. With neurological involvement ischemic or venous stroke, syncope and seizures can occur. Generally, clinical presentation is cerebral venous thrombosis. IIschemic stroke in children is associated with hyperviscosity and microstasis, and in adults with phlebotomy, microcytosis and traditional stroke risc factors such as hypertension, diabetes mellitus and cardiac rhythm disorders. Patients with uncorrected FT rarely survive adulthood. In this study, we present a case without total correction, who lived up to the age of 39 years and presented with arterial stroke instead of expected venous thrombosis, along with stroke mechanisms in the literature.
  • Küçük Resim Yok
    Öğe
    A comparison of risk factors and prognosis between intra and extracranial acute atherosclerotic stroke in the Turkish population: a prospective study
    (Taylor & Francis Ltd, 2016) Keheya, Sezgin; Tekatas, Aslan; Aynaci, Ozer; Utku, Ufuk; Solmaz, Volkan
    Background: The aim of this study was to compare the differences in risk factors and prognosis between acute stroke caused by definitive intracranial atherosclerosis (ICAS) or extracranial atherosclerosis (ECAS) in the Turkish population. Methods: This study was prospectively designed in a single centre and conducted with patients who were hospitalised due to acute ischaemic stroke. Inclusion criteria were the diagnosis of atherosclerotic ischaemic stroke, defined as more than 50% stenosis or occlusion in the arterial structure supplying the ischaemic area, having excluded other possible causes. Results: Information on 58 ICAS and 57 ECAS stroke patients was collected in a 13-month period. The ECAS patients had male gender predominance (p = 0.003). Ageing, stroke history and hyperlipidaemia were related with stroke severity in ECAS, and gender was associated with severity in ICAS. Hypertension and being female were related with poor prognosis in ICAS (p = 0.081 vs. 0.087). Congestive heart failure (p = 0.002) was associated with poor prognosis and alcohol with a favourable outcome (p = 0.087) in ECAS. Stroke severity was related with poor prognosis in both groups (p < 0.001). Conclusions: The prevalence of risk factors differs between ICAS and ECAS, and their influence differs for stroke severity and prognosis.
  • Küçük Resim Yok
    Öğe
    Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion
    (Elsevier Science Bv, 2014) Guler, Sibel; Utku, Ufuk; Aynaci, Ozer
    Background: The aim of this study was to assess infarct localization, clinical signs, and prognostic factors in cases with unilateral symptomatic total internal carotid occlusion. Methods: In total, 101 patients who had a diagnosis of symptomatic unilateral carotid occlusion in the Department of Neurology, Trakya University Faculty of Medicine, between January 2008 and May 2012, were included in this study. The relationship between infarct localizations and prognosis of patients was evaluated by cranial magnetic resonance imaging (MRI) and diffusion-weighted MRI. The condition of ipsilateral middle cerebral artery (MCA) and posterior communicating arteries (PCoAs) was assessed by cranial and cervical magnetic resonance angiography besides opposite carotid. Patients were evaluated by modified Rankin Scale in terms of prognosis at discharge and after 3 months. Furthermore, they were evaluated in terms of risk factors, such as cigarette and alcohol use, presence of temporary ischemic attack and stroke history, hypertension, diabetes mellitus, coronary artery disease, previous myocardial infarction, hyperlipidemia, and peripheral vascular disease. Results: Territorial infarct was commonly seen as acute ischemic stroke pattern especially in cases with a poor MCA circulation and insufficient collateral circulation. Development of territorial stroke, occlusion of MCA, and nonvisualization of PCoA were found to be associated with poor prognosis. Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality-associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.
  • Küçük Resim Yok
    Öğe
    EFFECTS OF CHADS2 SCORE, ECHOCARDIOGRAPHIC AND HAEMATOLOGIC PARAMETERS ON STROKE SEVERITY AND PROGNOSIS IN PATIENTS WITH STROKE DUE TO NONVALVULAR ATRIAL FIBRILLATION
    (Literatura Medica, 2019) Aynaci, Ozer; Tekatas, Asian; Aynaci, Gulden; Kehaya, Sezgin; Utku, Ufuk
    Introduction - The aim of this study is to evaluate utility of CHADS2 score to estimate stroke severity and prognosis in patients with ischemic stroke due to non-valvular atrial fibrillation (AF) in addition to evaluate effects of hematologic and echocardiographic findings on stroke severity and prognosis. Methods - This prospective study included 156 ischemic stroke cases due to non-valvular AF in neurology ward of Trakya University Medical School between March 2013-March 2015. National Institute of Health Stroke (NIHS) score was used to evaluate severity of stroke at admission. Carotid and vertebral Doppler ultrasonography findings, brain computed tomography (CT) and magnetic resonance imaging (MRI) of the cases were evaluated. Left atrial diameter and ejection fraction (EF) values were measured. CHADS2 score was calculated. Modified Rankin Scale was used to rate the degree of dependence. Effects of age and sex of the patients, presence of diabetes mellitus (DM), Congestive Heart Failure (CHF), Cerebrovascular Disease (CVD) and C-reactive protein (CRP) levels on CHADS2, NIHS, and mRS were evaluated. Results - In patients with age >= 75, mean NIHS score was 3.3 points and mean mRS score was 1.02 points higher, than in patient below 75 years of age. Compared with the mild risk group, cases in the high risk group had older age, higher serum D-dimer, fibrinogen and CRP levels and lower EF. A positive relation was detected between stroke severity and Hemorrhagic Transformation (HT), previous CVD history, and presence of CHF. A significant association was found between increased stroke severity and Early Neurological Deterioration (END) development. Older age, higher serum fibrinogen, D-dimer, CRP and lower EF values were associated with poor prognosis. History of CVD and presence of CHF were associated with poor prognosis. END development was found to be associated with poor prognosis. In the high-risk group, 30.3% (n = 33) had END. Among those in the high-risk group according to the CHADS2 score, END development rate was found to be significantly higher than in the moderate risk group (p < 0.05). There was a strong positive correlation between CHADS2 and NIHS scores. mRS score increased with increasing CHADS2 score and there was a strong correlation between them. Effect of stroke severity on prognosis was assessed and a positive correlation was found between NIHS score and mRS value. Discussion - Our study demonstrated the importance of CHADS2 score, haemostatic activation and echocardiographic findings to assess stroke severity and prognosis. Knowing factors which affect stroke severity and prognosis in patients with ischemic stroke may be directive to decide primary prevention and stroke management.
  • Küçük Resim Yok
    Öğe
    Lesion Patterns on Early Diffusion-weighted Magnetic Resonance Imaging and Ischemic Stroke Subtypes
    (Turkish Neurological Soc, 2020) Ayaz, Guven; Guldiken, Baburhan; Kehaya, Sezgin; Aynaci, Ozer
    Objective: The correct and rapid classification of the ischemic stroke subtype enables the determination of the proper treatment and a better prognosis. In this study, we investigated the association of ischemic stroke subtypes with early diffusion-weighted magnetic resonance imaging (MRI) lesion patterns. Materials and Methods: Three hundred forty-three consecutive patients with acute ischemic stroke were retrospectively evaluated. The ischemic stroke subtype for each patient was determined according to Trial of Org 10172 in Acute Stroke Treatment Classification. The lesion patterns in diffusion-weighted MRI in the first 24 hours of stroke were classified as single lesions, diffuse scattered lesions limited to one vascular area, and multiple territory lesions. The relationship between the diffusion-weighted MRI lesion patterns and ischemic stroke subtypes was investigated using the chi-square test. Results: The diffusion-weighted MRI lesion patterns showed significant differences among the ischemic stroke subtypes. Multiple territory lesions were more frequent in the cardioembolic and other determined causes groups compared with the large artery atherosclerosis group. Diffuse scattered lesions limited to one vascular area were more frequent in the large artery atherosclerosis, the unknown cause and the other determined causes groups than the others (p<0.01). Single lesions with a diameter smaller than 1.5 cm favored small vessel disease. None of the diffusion-weighted MRI lesion patterns was highly specific for any stroke subtype. Conclusion: Early diffusion-weighted MRI lesion distributions vary significantly among the ischemic stroke subtypes. When evaluated with other clinical findings, these data can help in the early determination of the ischemic stroke etiology.
  • Küçük Resim Yok
    Öğe
    Pruritus: Do A? fibers play a role?
    (Wiley, 2014) Tekatas, Aslan; Arican, Ozer; Guler, Sibel; Aynaci, Ozer; Dincer, Nejla
    Neuropathological and molecular basis of pruritus has not been clarified and the presence of certain specific neural circuits have been proposed. Our aim in this study was to evaluate the role of A fibers in the neural circuits of pruritus by cutaneous silent period (CSP). Thirty-six patients with chronic idiopathic generalized pruritus and 32 healthy controls were enrolled in the study. CSP and nerve conduction studies of upper and lower extremities were performed in both groups. Latencies of CSP in the upper and lower extremities were observed to be prolonged in the patient group compared with the controls while durations were shortened (all P<0.001). However, these values were not correlated with sex, age, duration or severity of the disease (all P>0.05). Our data suggest that pruritus may be developed by a nerve conduction abnormality in the afferent fibers of A, or cortical hypersensitivity, abnormality of the cortical inhibitory mechanisms or lack of inhibition in the intermediate spinal inhibitory neurons generating CSP. This topic needs to be evaluated thoroughly in larger series with more detailed studies.