Retrospective Analysis of Chronic Myeloid Leukemia Patients in Trakya University School of Medicine

Basit Öğe Kaydı
dc.contributor.authorAkay, Fatih Erkan
dc.contributor.authorKoçyiğit, Beliz
dc.contributor.authorTan, Berfin
dc.contributor.authorAtlı, Emine İkbal
dc.contributor.authorBaş, Volkan
dc.contributor.authorKırkızlar, Hakkı Onur
dc.date.accessioned2021-11-20T10:26:28Z
dc.date.available2021-11-20T10:26:28Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Genetik Anabilim Dalıen_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalıen_US
dc.description.abstractAims: This study aims to establish the data; including demographic features, molecular response status, disease characteristics, and survival rate of chronic myeloid leukemia patients treated with tyrosine kinase inhibitors in Trakya University School of Medicine. Methods: In this study, the data of 102 patients over 18 years old who were diagnosed with chronic myeloid leukemia in Trakya University School of Medicine between January 2003-October 2019 were analyzed retrospectively. Data was analyzed using SPSS 23.0.0.0. Results: The total number of patients in the study was 102. There were 95 (93.1%) patients on chronic phase and 6 (5.9%) patients on accelerated phase. Eighty-three (81.4%) of the patients had at least a major molecular response and 17 (16.7%) patients could not achieve at least a major molecular response. Conclusion: As our study showed, first line treatment with imatinib may not be enough for some of the patients to recover and therefore different TKIs such as dasatinib, nilotinib, bo-sutinib, and ponatinib are being used in the treatment of CML. Inadequate response, drug side effects and incompliances are the causes of switching the drug choice. Further studies are needed to thoroughly reveal the epidemiology and treatment regimens.Keywords: Chronic myeloid leukemia, tyrosine kinase, neoplasmsen_US
dc.identifier.dergipark640239en_US
dc.identifier.endpage74en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue3en_US
dc.identifier.startpage70en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/49952/640239
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/843906
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6059
dc.identifier.volume6en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic myeloid leukemiaen_US
dc.subjecttyrosine kinaseen_US
dc.subjectneoplasmsen_US
dc.titleRetrospective Analysis of Chronic Myeloid Leukemia Patients in Trakya University School of Medicineen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
6059.pdf
Boyut:
524.9 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Turkish Medical Student Journal
Makale Koleksiyonu
Makale Koleksiyonu