A Case Report With Fibrin-Associated Diffuse Large B-Cell Lymphoma Secondary to Cardiac Myxoma

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dc.contributor.authorAkay, Fatih Erkan
dc.contributor.authorBilaovi?, Nurija
dc.date.accessioned2021-11-20T10:26:57Z
dc.date.available2021-11-20T10:26:57Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractAims: To raise awareness for differential diagnosis of fibrin-associated diffuse large B-cell lymphoma with patients that have sustained chronic inflammation or are immunocompetent with a previous Epstein-Barr virus infection. Case Report: A 58-year-old male patient was admitted to the Clinical Center of Sarajevo University, Cardiovascular Surgery Department with the symptoms of getting tired quickly accompanied by dyspnea. His echocardiography findings exhibited a large polymorphic clavicle type highly mobile formation in his left atrium with a size of 76x23mm, intermittently prolapsing the annulus of the mitral valve and reaching the middle of the extended left ventricle. After the detection of a cardiac mass, the patient underwent surgery and had a total excision of the mass. His- topathological analysis showed a tumor made of stellate cells that form complex structures resembling wires together with an islet of plasma cells embedded in a myxoid/fibrinoid background. Immunohistochemically, lymphoma cells were positively stained for CD20, CD30, MUM1, and EBER. After excluding all other systemic manifestations of any other diseases, the patient was diagnosed with fibrin-associated diffuse large B-cell lymphoma, as a primary cardiac lymphoma, and myxoma. Conclusion: In conclusion, we are reporting a very rare case seen approximately 3% of all lymphomas in the Western Population associated with Epstein-Barr virus B-cell Lymphoproliferative disorders, therefore making them harder to diagnose due to limited experience. Albeit being an infrequent disease fibrin-associated diffuse large B-cell lymphoma should be an entity included in the differential diagnosis of the patients that have sustained chronic inflammation or are immunocompetent with a previous Epstein-Barr virus infection.en_US
dc.identifier.dergipark963060en_US
dc.identifier.endpage94en_US
dc.identifier.issn2148-4724
dc.identifier.issn2548-0030
dc.identifier.issue2en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/tmsj/issue/63592/963060
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1862043
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6235
dc.identifier.volume8en_US
dc.language.isoenen_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTurkish Medical Student Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiac myxomaen_US
dc.subjectdiffuse large B-cell lymphomaen_US
dc.subjectEpstein-Barr virus infectionen_US
dc.titleA Case Report With Fibrin-Associated Diffuse Large B-Cell Lymphoma Secondary to Cardiac Myxomaen_US
dc.typeArticleen_US

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