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Öğe Coronary microvascular dysfunction portends poor prognosis in the setting of chronic renal failure: Harnessing dual marker strategy for better risk-stratification?(Elsevier Ireland Ltd, 2014) Yalta, Kenan; Yilmaz, Mehmet Birhan[Abstract Not Available]Öğe Coronary slow flow: a potential prognostic marker correlating with the disease severity in renal failure?(Oxford Univ Press, 2010) Yalta, Kenan; Yilmaz, Mehmet Birhan; Yalta, Tulin; Sivri, Nasir; Refiker, Meltem[Abstract Not Available]Öğe Coronary syndrome Y: Should we focus more on extra-cardiac conditions including renal disease and its management?(Elsevier Ireland Ltd, 2011) Yalta, Kenan; Yilmaz, Mehmet Birhan; Yalta, Tulin; Sivri, Nasir; Yucel, Oguzhan[Abstract Not Available]Öğe Late Versus Early Myocardial Remodeling After Acute Myocardial Infarction: A Comparative Review on Mechanistic Insights and Clinical Implications(Sage Publications Inc, 2020) Yalta, Kenan; Yilmaz, Mehmet Birhan; Yalta, Tulin; Palabiyik, Orkide; Taylan, Gokay; Zorkun, CaferIn the setting of acute myocardial infarction (AMI), adverse myocardial remodeling (AMR) has been universally regarded as an early-onset phenomenon generally arising within the first few weeks (usually within days in the infarct zone) following myocardial injury. On the other hand, onset of cardiac morphological changes in this setting may potentially extend far beyond this time frame (usually beyond several months after the index AMI), suggesting a prolonged latent period in certain cases. In clinical practice, this delayed form of post-AMI remodeling, namely late AMR, has emerged as an interesting and underrecognized phenomenon with poorly understood mechanisms. Notably, systemic inflammation and associated growth factors seem to play a pivotal role in this setting. Accordingly, the present article primarily aims to discuss potential mechanisms and clinical implications of late AMR (in a comparative manner with its classical early counterpart) among AMI survivors along with a particular emphasis on potential benefits of certain anti-inflammatory strategies in this setting.Öğe Snapshot evaluation of heart failure in Turkey: Baseline characteristics of SELFIE-TR(Turkish Soc Cardiology, 2019) Yilmaz, Mehmet Birhan; Celik, Ahmet; Cavusoglu, Yuksel; Bekar, Lutfu; Onrat, Ersel; Eren, Mehmet; Kutlu, MerihObjective: Heart failure (HF) is an important health issue of the 21st century and the prevalence in Turkey has been reported as 2.9%. A national profile, frequency data, characteristics of different phenotypes, and risk factors have not yet been well established. The Snapshot Evaluation of Heart Failure Patients in Turkey (SELFIE-TR) was an analysis of a representative sample of HF patients from Turkey. Methods: A total of 23 centers with at least 2 cardiologists from the 12 NUTS-1 regions of Turkey were invited to participate in the research. The contributing centers shared the data of a consecutive enrollment of HF patients, as confirmed by an investigator, on a pre-selected day of each week for the month of October or November of 2015. Results: The mean age of the entire cohort was 63.3 +/- 13.3 years (male/female ratio: 751/303, 71.3%/28.7%). There were 712 acute HF patients and 342 chronic HF patients. The total number of HF patients with reduced ejection fraction (HFrEF), heart failure with mid-range ejection fraction, and heart failure with preserved ejection fraction was 801 (75%), 176 (16.7%), and 77 (7.3%), respectively. The patients with chronic HF were younger than those with acute HF (61.1 +/- 13.3 years vs 67.9 +/- 12.1 years; p<0.001). Among the whole cohort, hypertension was observed in 46%, diabetes mellitus was present in 27.5%, chronic obstructive pulmonary disease was present in 12.8%, and previous myocardial infarction was noted in 45.2%. In patients with HFrEF, the use of an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, a beta blocker, or a mineralocorticoid receptor antagonist was noted in 74.7%, 89.7%, and 60.9%, respectively. Conclusion: The SELFIE-TR findings provide important insight, since it is the first study to make a snapshot of HF patients in our country. These data may help to create standardized prevention and treatment strategies.