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Öğe Tc-99m MIBI filling pattern in a photopenic area of a Tc-99m MDP scan in a patient with metastatic bone involvement of breast carcinoma(Lippincott Williams & Wilkins, 2002) Altun, GD; Uzal, C; Hacimahmutoglu, S; Pekindil, G; Sarikaya, A; Yigitbasi, NÖA 71-year-old woman had locally advanced invasive breast cancer in July 1997. She underwent modified radical mastectomy for left breast cancer in October 1997 after she had been treated with six of courses neoadjuvant chemotherapy and local radiation therapy. She was referred for bone scintigraphy due to bone pain in September 1999. The bone scan showed metastatic involvement in the left temporoparietal area as increased Tc-99m MDP uptake with large central photopenia. The computed tomographic (CT) scan of the cranium revealed lytic bone lesions located in the same region, which was irregularly contoured. Tc-99m MIBI imaging was performed 1 week after the bone scan. Increased uptake without central photopenia was observed in the same area as the bone scan abnormality. It was described as a Tc-99m MIBI filling pattern of the photopenic area seen with Tc-99m MDP.