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Öğe A case of cebocephaly associated with abnormal genitalia(Elsevier Ireland Ltd, 2007) Duran, Ridvan; Aladag, Nukhet; Vatansever, Ulfet; Acunas, Betul; Puyan, Fulya Oz; Varol, Fusun G.Holoprosencephaly is frequently accompanied by midline facial abnormalities such as hypotelorism, cyclopia, etmocephaly, and cebocephaly. Cebocephaly is a very rare congenital anomaly combining alobar holoprosencephaly, ocular hypotelorism, and a proboscis-like nose with single nostril. There is only one cebocephaly case with abnormal genitalia. We report to our knowledge the second case of cebocephaly associated with abnormal genitalia in the relevant literature. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Case of The Month(Aves, 2005) Vatansever, Ulfet; Duran, Ridvan; Acunas, Betul[Abstract Not Available]Öğe Comparison of respiratory morbidity in late preterm infants and intrauterine growth retarded infants at school-age(Marmara Univ, Fac Medicine, 2022) Us, Mahmut Caner; Vatansever, Ulfet; Duran, Ridvan; Acunas, BetulObjective: We aimed to determine respiratory morbidity of late pretenn infants versus infants with intrauterine growth retardation (IUGR) at school-age. Patients and Methods: Late preterm appropriate for gestational age (AGA) infants (34-36, 6/7 weeks) (Group 1), IUGR infants (Group 2), extremely preterm AGA (Group 3) and term AGA infants (Group 4) born between 2004 and 2008 were included in this case-control study and assessed for respiratory morbidity at school-age. We evaluated the impact of late preterm compared with IUGR and term gestation on respiratory morbidity by using validated American Thoracic Society - Division of Lung Diseases (ATS-DLD-78-C) and the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires. Questionnaires on wheezing, infectious respiratory morbidity, and physician-diagnosed asthma panels were constituted and groups were compared. Results: A total of 160 patients were enrolled in the study and 97 (60.6%) of them were boys. Respiratory morbidities at school-age were found to be significantly higher in both late preterm and IUGR groups when compared to term controls. Each weekly increase in gestational age reduced the risk for wheezing episodes (OR perGW:0.82,95%CI:0.71-0.97, p:0.02). Regarding infectious respiratory morbidities, there was a significant increase when the number of people living at home increased (OR perperson:1.79,95%CI:1.12-2.87, p:0.01), and a decrease in female gender (OR:0.41,95%CI:0.17-0.99, p:0.04) and in the week of gestation (OR perGW:0.84,95%CI:0.71-1.00, p:0.04). Atopic dermatitis (OR:5.26,95%CI:1.57-17.69, p<0.01) and maternal asthma (OR:5.38,95%CI:1.17- 24.60, p:0.03) history were found to be risk factors for asthma. Conclusion: Being IUGR may be an important risk factor for respiratory morbidity at school-age. Further studies are needed on this subject.Öğe Dietary Intakes of Adolescents Living in Edirne, Turkey(Routledge Journals, Taylor & Francis Ltd, 2008) Garipagaoglu, Muazzez; Oner, Naci; Vatansever, Ulfet; Inan, Mustafa; Kucukugurluoglu, Yasemin; Turan, CagriObjective: To assess the dietary intakes of the adolescents in the area of Edirne, Turkey. Design: Cross-sectional, prospective, epidemiological study. Settings and Subjects: Our study group consists of 1944 adolescents aged between 12 to 17 years; 940 females and 1004 males. Interventions: Three-day self-reported food records were collected from the subjects and evaluated by a nutrient database pro.-ram. Reported nutrient intake data were analyzed for gender differences. Minitab statistical program was used to compare nutritional data of subjects. Results: Energy, calcium, magnesium, folic acid, vitamins A, E, thiamine. and fiber intakes of whole adolescents, and also iron intakes of female adolescents were most likely to be inadequate compared with the recommendations. Iron, calcium, folic acid, thiamine, and fiber intakes were below two thirds of RDA/DRI in a large proportion of the adolescents. The intakes of protein, riboflavin, vitamin C, phosphorus and zinc were found to be adequate in a large percentage of the subjects. Forty eight percent of females and 60.1 % of males were below 2/3 of the RDA for energy. Conclusion: Pediatricians and dietitians should train the adolescents living in our region and our country on practical strategies for making healthy food choices rich in nutrient content relative to energy value to ensure intakes that approach the recommendations.Öğe The effect of prenatal breast-feeding and breast-milk training given to expectant mothers on the behaviour of breast-feeding(Turkish Pediatrics Assoc, 2011) Onbasi, Senay; Duran, Ridvan; Ciftdemir, Nukhet Aladag; Vatansever, Ulfet; Acunas, Betul; Sut, NecdetAim: At present, training given during pregnancy has been shown to affect the beginning, percentage and duration of breast-feeding. The present study aims to inform expectant mothers about breast-milk and breast-feeding via a prenatal training and to emphasize the advantages of the training. Material and Method: Trainings on and breast-milk were held for the pregnant womens on two days in a week. Each expectant mother was given prenatal training once. Data were collected via a questionnaire composed of 42 questions about breast-milk and breastfeeding. Statistical 7.0 package was used for statistical analysis. All numeric values were expressed as mean +/- SD and n (%). A p value of < 0.05 was considered statistically significant. This study was approved by the Trakya University Local Ethics Committee. Results: A total of 190 mothers, 90 in training group and 100 in control group were included in the study. A significant difference in the breast-feeding percentage was found in the first six months. The bottle feeding was found to be the case of breast-feeding for less than six months. Conclusions: It is concluded in the present study that the percentage and duration of feeding only with breast-milk could be increased if pregnant women are given training about breast-milk. (Turk Arch Ped 2011; 46: 75-80)Öğe Gastric pneumatosis intestinalis(Lippincott Williams & Wilkins, 2006) Duran, Ridvan; Vatansever, Ulfet; Aksu, Burhan; Acunas, Betul[Abstract Not Available]Öğe Intestinal perforation: Rewiev of our experience in the neonatal period(Aves, 2007) Duran, Ridvan; Vatansever, Ulfet; Aksu, Burhan; Inan, Mustafa; Acunas, BetulAim: Despite rapid advances in neonatal intensive care, intestinal perforation (IP) has remained a major and life- threatening complication in neonates. Spontaneous intestinal perforation (SIP) is a recently defined entity, which is mostly seen in very low birthweight (VLBW) newborn infants. We want to report and discuss etiology, clinical features, and outcome of our IP cases. Material and Method: Charts of thirteen infants with IP was reviewed in terms of gender, birth weight, gestational age, day of perforation, diagnosis, location of perforation, type of surgery performed, and clinical outcome. Results: There were nine boys and four girls. Eight of them were preterm. Mean perforation time was day nine postnatally. 11 infants had the causes of IP including meconium ileus (n= 6), necrotizing enterocolitis (NEC) (n= 4), esophageal atresia (n= 1), following malrotation surgery (n= 1) and, three of them were on mechanical ventilator support. Two VLBW infants developed IP following oral ibuprofen administration. Perforation occurred in the distal ileum in the majority of infants. Conclusions: We found that essentially NEC, meconium ileus, and mechanical ventilation were associated with intestinal perforations and SIP following oral ibuprofen administration was observed in two preterm infants.Öğe Knowledge gained and retained by neonatal nurses following neonatal resuscitation program course(Aves, 2007) Duran, Ridvan; Aladag, Nukhet; Sen, Filiz; Vatansever, Ulfet; Acunas, BetulAim: The aim of our study was to evaluate the knowledge gained and retained by neonatal nurses following neonate resuscitation program (NRP) course. Material and Method: The study comprised 30 neonatal nurses. A 3-day course was held in the Department of Pediatrics, Medical School, Trakya University. A written test with 80 questions derived from the standard test contained in the American Heart Association and the American Academy of Pediatrics Neonatal Resuscitation Manual was given to the neonatal nurses before, at the end and six months after the course. Results: The percentages of correct answers significantly improved immediately after the course (% 33,6 +/- 10; % 92,4 +/- 6,1). The percentages at the six months follow-up-course test were significantly reduced as (% 56,2 +/- 12,6) compared to the post-course results, but remained higher with respect to pre-course results. The knowledge gained and retained had increased significantly after the NRP course particularly in the administration of medications and fluids step. Conclusions: These data suggest that a NRP course may be required prior the end of the usual two-year certification period of NRP courses especially one year after the course.Öğe Neurodevelopmental and psychiatric assessments at corrected age of 1-3 years in very preterm infants(Turkish Pediatrics Assoc, 2011) Gorker, Isik; Vatansever, Ulfet; Acunas, BetulAim: To assess the neurodevelopmental and psychiatric outcomes of very preterm vs preterm infants at 1-3 years of corrected age. Material and Method: Between years 2005-2008, premature infants followed-up in the NICU designated as Group 1 (<32 wks;n=36) were evaluated in comparison to Group 2 (33-37wks; n=56) with the approval of Ethics Committee (TUTFEK 2008/083) in terms of neurodevelopmental and psychiatric development by using Denver developmental screening test, the brief infant toddler social emotional assessment-childcare provider version. Mothers' psychiatric symptoms were assessed by the brief symptom inventory. Socioeconomic status was determined by using SES scale. t-test or Mann-Whitney U tests, chi-square and Spearman tests were used for statistical analysis. Results: In Group 1, paternal education level and psychodevelopmental score was lower than group 2, abnormal outcome in Denver developmental test was more frequent. Psychiatric problem score was higher in boys, whereas psychodevelopmental score was higher in girls. Psychosocial developmental score was lower in those infants with intraventricular hemorrhage and this score showed positive correlation with Denver developmental test results. There was no difference between the two groups in terms of brief symptom inventory. Conclusions: Although very preterm infants more frequently showed abnormal neuropsychological development, they were not significantly different with regard to psychiatric problems. Girls were more advantegous than boys in terms of psychodevelopment. We conclude that these findings should be validated by larger and further studies. (Turk Arch Ped 2011; 46: 280-5)Öğe A novel mutation in the ABCA12 gene in a Turkish case of Harlequin ichthyosis(Lippincott Williams & Wilkins, 2015) Gurkan, Hakan; Fischer, Judith; Ulusal, Selma; Vatansever, Ulfet; Hartmann, Britta; Tozkir, Hilmi; Schlipf, Nina[Abstract Not Available]Öğe De Novo Subtelomeric 6p25.3 Deletion with Duplication of 6q23.3-q27: Genotype-Phenotype Correlation(Georg Thieme Verlag Kg, 2020) Atli, Emine Ikbal; Gurkan, Hakan; Atli, Engin; Vatansever, Ulfet; Acunas, Betul; Mail, CisemDuplications of 6q and deletions of 6p have been reported in more than 30 cases of live born infants and given rise to widespread abnormalities recognizable as a specific clinical syndrome. Different phenotypes have been described with variable clinical signs. Most cases involve the coexistence of unbalanced translocations affecting one or the other of the chromosomes. However, duplication of both chromosome 6q and deletion of 6p regions have been reported in only a few cases. Here, we report the first duplication of chromosome band 6q23.3-q27 with deletion of 6p25.3. This is the first case in the literature involving changes to these specific chromosomal regions; a medium size duplication of the distal long arm and smaller deletion of the terminal short arm of chromosome 6. In the literature, there are no other cases where these two specific chromosomal aberrations are observed together. Conventional chromosome analysis was performed to investigate the patient. Chromosome structure was identified using fluorescence in situ hybridization for subtelomeric regions of chromosome 6 and array comparative genomic hybridization analysis (array-CGH).Öğe A premature infant with H-type tracheoesophageal fistula demonstrated by scintigraphic technique(Lippincott Williams & Wilkins, 2006) Vatansever, Ulfet; Acunas, Betul; Salman, Tansu; Altun, Gulay; Duran, RidvanPurpose: Congenital tracheoesophageal fistula (TEF) without esophageal atresia is commonly known as H type. This is extremely rare in infants. The rarity of the condition, its nonspecific symptomatology, and limitations in its demonstration by contrast radiology and endoscopy contribute to delays between first presentation and confirmation of the diagnosis. Our aim was to demonstrate a congenital H-type tracheoesophageal fistula by using Tc-99m sulfur colloid scintigraphy. Materials and Methods: A case report. Results: A preterm female infant was born by cesarean section at 34 weeks gestation. After many attempts of feeding, she developed apnea, resolving spontaneously, peroral cyanosis, pallor, hypersalivation, and abdominal distension, even when she was being fed by an orogastric tube. With this complex symptomatology, she was suspected to have an H-type TEF Because of prematurity and recurrent respiratory problems of the infant and the high risk of aspiration of contrast material during a cineradiographic procedure, and also because of the invasive nature of the endoscopic procedure as well as the requirement of general anesthesia, the diagnosis was made by using Tc-99m sulfur colloid scintigraphy and confirmed at operation. Conclusion: Demonstrating a congenital H-type tracheoesophageal fistula by using radionuclide imaging is an easily applicable technique.Öğe Seroprevalence of autoimmune thyroiditis and celiac disease in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey(Turkish Soc Gastroenterology, 2010) Soyucen, Erdogan; Yilmaz, Sema; Celtik, Coskun; Vatansever, Ulfet; Oner, Naci; Karasalihoglu, SerapBackground/aims: We aimed to estimate the seroprevalence of celiac disease, a gluten-sensitive enteropathy, and autoimmune thyroiditis in children with insulin-dependent diabetes mellitus in the Thrace region of Turkey. Methods: The population studied consisted of 33 children with insulin-dependent diabetes mellitus and 41 healthy children with demographic features similar to the study subjects. Free triiodothyronine, free thyroxine, thyroid-stimulating hormone, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, IgA, anti-endomysium IgA, and anti-gliadin IgA were measured in all cases and controls. Results: The serum levels of free triiodothyronine and free thyroxine were within the normal range in all cases. However, in one patient who had anti-thyroid peroxidase and anti-thyroglobulin antibodies, the thyroid-stimulating hormone level was high despite a normal free triiodothyronine and free thyroxine value. Ultrasonographic findings confirmed thyroiditis in this patient. Anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies, anti-endomysium IgA and anti-gliadin IgA were detected in 15.4%, 6%, 9.1% and 3% of the diabetic cases, respectively. None of these antibodies was detected in the control group. In the diabetic group, the seroprevalences of the antithyroid peroxidase antibodies and the anti-endomysium IgA were statistically higher than in the control group (p<0.05). Conclusions: Children with insulin-dependent diabetes mellitus in our region should undergo periodic screenings for autoimmune thyroiditis and celiac disease.
