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Öğe Does continuous or intermittant use of desflurane has effects on brain natriuretic peptide (BNP) levels in patients undergoing coronary artery bypass graft surgery(Lippincott Williams & Wilkins, 2014) Baysal, A.; Sagiroglu, G.; Dogukan, M.; Toman, H.[Abstract Not Available]Öğe Does early use of bilevel positive airway pressure (bipap) in cardiothoracic intensive care unit prevent reintubation?(E-Century Publishing Corp, 2014) Sagiroglu, G.; Baysal, A.; Copuroglu, E.; Gul, Y. G.; Karamustafaoglu, Y. A.; Dogukan, M.Introduction: Non-invasive ventilation (NIV) is a preferred treatment in acute respiratory failure after operations. Our aim is to investigate the success of early use of bilevel positive airway pressure (BIPAP) after cardiac or thoracic surgeries to prevent reintubation. Methods: In a prospective randomized study, 254 patients were divided into two groups depending on the time period between extubation and the application of BIPAP. In Group 1 BIPAP was applied after extubation within 48 hours after surgery following fulfilling of acute respiratory failure criterias whereas, in Group 2, BIPAP was applied one hour after extubation for two episodes of 20 minute duration and 3 hours apart. Arterial blood gas values (pH, PaO2, PaCO2) at first and fourth hour after BIPAP were collected. Results: In comparison between groups, no significant differences were observed for arterial blood gas values of pH and PaCO2 at baseline, one and four hours after BIPAP (p > 0.05) however, the PaO2 values at one and four hours after BIPAP were significantly better in Group 1 in comparison to Group 2 (p < 0.001, p < 0.001; respectively). Reintubation rate was 14 patients (11%) in Group 1 and 7 patients (5.5%) in Group 2 (p = 0.103). Conclusions: The early and prophylactic use of BIPAP after cardiac or thoracic operations did not provide diminished rates in the postoperative complications such as reintubation.Öğe DOES EARLY USE OF BILEVEL POSITIVE AIRWAY PRESSURE (BIPAP) IN CARDIOTHORACIC INTENSIVE CARE UNIT PREVENT REINTUBATION?(Springer, 2014) Sagiroglu, G.; Baysal, A.; Capuroglu, E.; Gul, Y. G.; Karamustafaoglu, Y. A.; Dogukan, M.[Abstract Not Available]Öğe Does the residual blockade after administration of neostigmine and atropine is reversible with the use of sugammadex?(Lippincott Williams & Wilkins, 2014) Baysal, A.; Sagiroglu, G.; Ozkaynak, I; Dogukan, M.[Abstract Not Available]Öğe The Presence of Donor-Specific Antibodies in Renal Transplantation(Elsevier Science Inc, 2012) Tozkir, H.; Sagiroglu, T.; Kilicarslan-Ayna, T.; Tan, S.; Copuroglu, E.; Sagiroglu, G.; Sari, G.Determining the presence of anti-HLA antibodies before transplantation is an important factor to prevent loss of function among renal transplantations. In addition, recent studies have shown that not only the pretransplantation existence of anti-HLA antibody but also posttransplantation donor-specific antibodies (DSA) and non-donor-specific antibodies are significantly associated with allograft rejection or loss of graft function. This study presented DSA among patients after renal transplantation together with graft function and survival.Öğe Sublingual vs. intranasal dexmedetomidine sedation for flexible fiberoptic bronchoscopy procedure: a retrospective comparative study(Verduci Publisher, 2023) Yanik, F.; Sagiroglu, G.; Karamustafaoglu, Y. A.OBJECTIVE: Flexible fiberoptic bronchoscopy (FOB) is an often-employed invasive method in diagnosing, staging, and treating lung diseases. Conventional sedative agents facilitate this process. Dexmedetomidine (DM) has low side effects and is easy to administer for trans-mucosal absorption. This study aimed to investigate trans-mucosal DM used with local anesthesia during the FOB procedure. PATIENTS AND METHODS: Fifty-nine cases were retrospectively analyzed who had undergone diagnostic flexible fiberoptic bronchoscopy (FOB) in our clinic between September 2016 and September 2019. The two methods (Group 1: Sublingual, and Group 2: Intranasal) employed during the FOB procedure for the local anesthesia were compared. RESULTS: Fifty-nine patients were included in the study, wherein forty-six were males (77.9%), and thirteen (22.1%) females had a mean age of 58.02 +/- 8.7 years (range: 39-72 years). Thirty-three patients were in Group 1 (Sublingual) and 26 in Group 2 (Intranasal). No significant differences were there between groups regarding age, gender, body mass index, or ASA physical status. Modified Aldrete Score >9 was significant to reach with time as a correlation between operator and patient satisfaction. Sedation scores for groups at 1st, 9th, 12th, and 15th min were similar. Excessive coughing was observed in two (7.7%) patients of Group 2 but in none of Group 1 (p=0.105). Patients in both groups had no complaints of swallowing, excessive body movement, or lower oxygen saturation during examination (p>0.05). There were no complications (hypotension, bradycardia, respiratory depression, allergy, permanent amnesia, nausea, and vomiting) observed in patients. CONCLUSIONS: Our study results revealed that easily administered trans-mucosal dexmedetomidine sedation is safely applied during flexible fiberoptic bronchoscopy for adequate sedation, high satisfaction, and low complication rates with no significant difference in sublingual or intranasal administration.
