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Öğe Comparative evaluation of various low-level laser therapies on bone healing following tooth extraction: An experimental animal study(Churchill Livingstone, 2018) Cirak, Erkan; Ozyurt, Anil; Peker, Tuncay; Omeroglu, Suna; Gungor, Mehmet NadirPurpose: The aim of this study was to evaluate the effects of helium-neon and gallium-aluminumarsenide lasers with various doses on bone healing following tooth extraction. Materials and Methods: Maxillary right incisor teeth of 30 female albino Wistar rats were extracted. Five groups were established: four groups treated with helium-neon or gallium-aluminum-arsenide lasers and a control group. Both laser groups' rats received energy doses of 6 J/cm(2) and 10 J/cm(2) for 7 days. At the end of 30 days, all subjects were sacrificed for histological and morphological evaluations. Results: Laser groups showed faster bone healing and gallium-aluminum-arsenide lasers increased vascular immunoreactivity. The most widespread organized bone formation in the extraction socket was observed in the gallium-aluminum-arsenide laser group with the energy dose of 10 J/cm(2) (p < 0.05). Conclusion: This study demonstrated that low-level laser therapies were effective on alveolar bone healing and that an energy dose of 10 J/cm(2) did not have an inhibition effect on bone regeneration. (C) 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.Öğe Effect of gel formulation obtained from Fomes fomentarius on bleeding and clotting time: A pilot study(Istanbul Univ, Fac Pharmacy, 2020) Gedik, Gulsah; Asan, Hulya; Ozyurt, Anil; Alli, Hakan; Asan, Ahmet; Nazli, Hakan; Sarp, OnderBackground and Aims: Fomes fomentarius (L.) Fr. (jar fungus) has been used extensively in the past by surgeons, barbers, dentists, and is therefore called surgeon's fungus. The hemostatic properties of F. fomentarius extracts are important in medicine. The aim of this study was to investigate the effect of the gel formulation obtained from Fames Famentarius on bleeding and clotting time in rat models. Methods: The gel was made for this purpose and a cross-linked polymer of acrylic acid was used as a gelling agent. Results: The outcomes of the characterization analysis indicate the development of a successful gel formulation with optimum characteristics. Data from the antimicrobial study showed a good inhibition zone, with the strongest values against Klebsietta pneumaniae, Candida krusei, C. tropicalis, C. guitliermondii. The gel administration shortened the hemostasis time after bleeding from skin incisions by 63.9% and tail incisions by 55.63% from the original time. For coagulation time, these results are determined as 71.56% from the original time. The gel administration shortened the coagulation time after bleeding from the tail incisions by 69.9% from the original time. Conclusion: Our preliminary study showed that the gel formulation obtained from F. fomentarius is a potent hemostatic agent in a rat-bleeding model.Öğe Effects of Low-Level Laser Therapy With a Herbal Extract on Alveolar Bone Healing(W B Saunders Co-Elsevier Inc, 2018) Ozyurt, Anil; Elmas, Cigdem; Seymen, Cemile Merve; Peker, Veysel Tuncay; Altunkaynak, Bulent; Gungor, Mehmet NadirPurpose: This study investigated the effect of a gallium-aluminum-arsenide (GaAlAs) diode laser used in low-level laser therapy (LLLT) with the application of Mecsina Hemostopper on mandibular alveolar bone healing. Materials and Methods: Standard semispherical bone defects were created in left mandibular diastema sites of 32 female Long-Evans rats. Experimental animals were allocated to 1 of 4 groups: control group (no treatment), laser group (GaAlAs LLLT), Mecsina group, and laser-Mecsina combination group. Liquid Mecsina 0.01 mL was applied to the bone defects. Laser treatment was performed for 7 days after surgery at an energy dose of 10 J/cm(2). All animals were sacrificed to observe hard tissue healing histologically, immunohistochemically, and radiologically at 30 days after surgery. Results: Histologic assessment showed significantly more calcified tissue areas and significantly more osteoblast cells in the laser and laser-Mecsina groups than in the other groups (P <.01). Qualitative morphologic assessment showed that more bone tissue was present in the laser-Mecsina group than in the other groups. Conclusion: This study showed that LLLT, Mecsina application, and combined treatments were effective in healing alveolar bone among all tested treatment modalities. (C) 2017 American Association of Oral and Maxillofacial SurgeonsÖğe Investigation of implant internal screw loosening under hyperbaric conditions: An in vitro study(Wiley, 2021) Ozyurt, AnilBackground and purpose The internal screw has an essential role in carrying abutment and prosthesis loading. Some dental implant patients such as scuba divers, mineworkers, and hyperbaric oxygen patients are exposed to hyperbaric atmospheres. The aim of this study was to investigate internal screw loosening under hyperbaric conditions. Materials and methods Forty-two dental implants were placed into plexiglass blocks. Abutments were fixed with internal screws by 25 Ncm torque force. Groups were set as control, 2.8-bar air pressure, and 4-bar air pressure groups. Hyperbaric groups were subdivided and exposed to either one or six cycles. Removal torque values were measured with a digital torque meter. Data were analyzed statistically using analysis of variance and Tamhane's T2 tests, considering p < 0.05 as the level of statistical significance. Internal screw threads were qualitatively observed under magnification. Results Four-bar groups showed the lowest removal torque values among all groups (p < 0.001). 2.8-Bar groups did not show significant differences compared with control groups. There was no statistically significant difference between the one and six pressure cycle subgroups in each group. All internal screw threads had various deformations. Conclusion Four-bar air pressure had a significant effect on internal screw loosening. Internal screw tightening protocols should be reconsidered for patients exposed to advanced hyperbaric conditions.Öğe Is Resonance Frequency Analysis a Reliable Evaluation for Primary Stability of Implants Without Apical Contact?(Quintessence Publishing Co Inc, 2022) Ozyurt, Anil; Bilmenoglu, CaglarPurpose: The primary stability of dental implants is one of the most crucial factors for providing long-term success of osseointegration. Vertical deficiencies, such as those due to maxillary sinus pneumatization, may cause a severe vertical limitation to residual bone height. This study aimed to examine the primary stabilization of implants without apical contacts. Materials and Methods: Eighty bone-level implants (4.1-mm diameter/10-mm length) were placed into polyurethane test blocks without apical contacts. According to coronal bone-to-implant contact, groups were set as 4,6, 8, and 10 mm, respectively. Resonance frequency analysis (RFA) using a SmartPeg was performed separately toward the transversal and horizontal axes by two independent researchers. Data were statistically compared for interobserver and among groups. Results: Interobserver reliability varied from moderate to excellent (intraclass correlation coefficient [ICC]: 0.629 to 0.985). There were no significant differences among the 6 mm, 8 mm, and 10 mm groups, although the 4 mm group showed the significantly lowest stability (P < .001). Transversal and longitudinal measurements of the same groups did not show a parallel correlation statistically. Conclusion: RFA values may be affected by the finger torque in tightening of the SmartPeg among different researchers. Fully placed implants did not significantly show the highest stability among various apically contactless groups. Consequently, RFA should not be used alone to evaluate primary stability for implants without an apical contact.Öğe Primary Stability in Various Levels of Impacted Implants: An Ex Vivo(Allen Press Inc, 2021) Bilmenoglu, Caglar; Ozyurt, Anil; Cilingir, Ahmet Altug; Turan, Fatma NesrinThe aim of this study was to examine the primary stabilization of different vertically impacted bone implants. Implant stability was measured by resonance frequency analysis. Forty-five dental implants were used and divided into 3 groups. Group 1 was placed 4 mm (1/3 impacted), group 2 was placed 8 mm (2/3 impacted), and group 3 was placed 12 mm (fully impacted). Implant stability quotient values were measured on the longitudinal and transversal axis by 2 independent researchers. The fully impacted group showed the significantly highest value among the groups (P , .05). There were statistically varying implant-stability quotient values between researchers. None of the 1/3-impacted implants' value reached a 70 implant-stability quotient value.