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    Factors affecting surgical outcomes after superior mesenteric artery thromboembolism
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2017) Yuksel, Volkan; Guclu, Orkut; Yilmaz, Elif Cicek; Huseyin, Serhat; Ozkara, Taha; Sezer, Yavuz Atakan; Canbaz, Suat
    Background: In this study, we aimed to evaluate the operative results of superior mesenteric artery thromboembolism and influential factors for mortality in patients undergoing surgery for acute mesenteric ischemia. Methods: Between January 2011 and December 2016, 28 consecutive patients (15 males, 13 females; mean age 71.2 +/- 10 years; range 48 to 89 years) diagnosed and operated for acute mesenteric ischemia were included in the study. The results of open revascularization procedures and influential factors for mortality were retrospectively analyzed. Results: Abdominal pain was the major complaint, followed by nausea and vomiting. The diagnosis was confirmed by computed tomography angiography and Duplex ultrasonography. Thromboembolectomy was performed in the majority of the patients, while autologous saphenous vein bypass and transposition were performed in eligible patients. Revascularization procedures prevented bowel resection in 10 patients. The mortality rate was 35.7% due to respiratory, renal, and cardiac pathologies. Postoperative respiratory failure and admission to hospital later than six hours after the onset of abdominal pain were identified as the factors affecting mortality. Conclusion: Our study results showed that postoperative respiratory failure and late admission after the onset of abdominal pain were associated with postoperative mortality, whereas intestinal resection requirement did not contribute to the mortality rates. Based on our study results, we suggest that exploratory laparotomy and thromboembolectomy are essential in evaluating the viability of the bowel and in continuation of the mesenteric perfusion.
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    Pericardial SCUBE1 levels may help predict postoperative results in patients operated on for coronary artery bypass graft surgery
    (Clinics Cardive Publ Pty Ltd, 2021) Ozkara, Taha; Yuksel, Volkan; Guclu, Orkut; Huseyin, Serhat; Ozgun, Eray; Turan, Fatma Nesrin; Canbaz, Suat
    Introduction: Signal peptide-CUB epidermal growth factor like domain-containing protein (SCUBE1) is a newly described, secretable and measurable cellular surface protein associated with atherosclerotic lesions in humans, which may be involved in hypertension and cardiovascular pathologies. We aimed to detect normal SCUBE1 levels in pericardial fluid and investigate the effects of SCUBE1 values on postoperative outcomes after coronary artery bypass surgery. Methods: Between February 2016 and March 2017, 184 consecutive patients were included in the study. Group 1 consisted of patients with unstable angina pectoris, group 2 of patients with non-ST-elevation myocardial infarction, group 3 of patients with ST-elevation myocardial infarction, and group 4 consisted of patients operated on due to non -coronary reasons. Pericardial fluid and arterial blood SCUBE1 values, demographic variables and postoperative results were noted and compared. Results: Normal SCUBE1 level in pericardial fluid was 0.049 +/- 0.061 ng/ml. Arterial SCUBE1 levels of smokers were higher. Pericardial SCUBE1 levels were higher in patients requiring postoperative intra-aortic balloon pump support and patients needing peri-operative temporary cardiac pacing. High pericardial SCUBE1 values did not correlate with postoperative stroke, prolonged intensive care unit stay and mortality. Conclusion: High levels of pericardial SCUBE1 may help us predict the need for postoperative intra-aortic balloon pump support and the need for temporary cardiac pacing, however they were not helpful in predicting prolonged intensive care unit stay and early postoperative mortality.