Yazar "Ozguven, Y." seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim Yok
    Öğe
    Effect of Irradiation on the Shear Bond Strength of Self-adhesive Luting Cement in Different Preparation Depths
    (Medknow Publications & Media Pvt Ltd, 2017) Sahin, O.; Dede, D. O.; Koroglu, A.; Ozguven, Y.; Dogan, D. O.
    Objective: The purpose of this study was to evaluate the effects of pre- and post-irradiation application on the shear bond strength of self-adhesive luting cements to dentin and enamel. Materials and Methods: Thirty-two extracted human maxillary incisor teeth were used in this study. Teeth were divided into two main groups according to preparation depth (0.5 mm and 1 mm) as Group E and Group D and were divided into four subgroups according to treatment protocol (n = 12). Teeth were irradiated and preparation was done after radiation. Adhesive luting cement was placed on the irradiated enamel and dentin surface (Groups E1, D1). Preparation was done before irradiation and resin cement was placed on the irradiated enamel and dentin surface (Groups E2, D2). The resin cement was first placed on their enamel and dentin surfaces and then the specimens were irradiated (Groups E3, D3). Irradiation was done with a total dose of 60 Gy, applied in fractions over 6 weeks for each groups (2-Gy/day fractions, 5 days per week). Nonirradiated groups were determined as controls groups (Groups C1, C2). The shear bond strengths of adhesive luting cement were examined. Results: According to the two-way ANOVA results, depth of preparation and treatment protocol and their interactions were significant on shear bond strength of resin cement (P < 0.05). Conclusions: This study detected significant differences between the irradiated and nonirradiated groups, probably due to the changes in the crystalline structure of dental hard tissues.
  • Küçük Resim Yok
    Öğe
    The impact of everolimus on pulmonary damage with radiotherapy: Results of an experimental study
    (Elsevier Sci Ltd, 2015) Eren, M.; Eren, A. Ay; Yucel, B.; Ozguven, Y.; Matsuno, R. K.; Altun, A.; Kilickap, S.
    [Abstract Not Available]
  • Küçük Resim Yok
    Öğe
    The impact of everolimus on radiation-induced pulmonary fibrosis in wistar albino rats: Results of an experimental study
    (Amer Assoc Cancer Research, 2016) Eren, M. F.; Eren, A. Ay; Yucel, B.; Elagoz, S.; Ozguven, Y.; Altun, A.; Kilickap, S.
    [Abstract Not Available]
  • Küçük Resim Yok
    Öğe
    Investigation of cardiac and pulmonar doses in patients with left sided breast cancer treated by radiotherapy with deep inspiration breath hold technique
    (Ijrr-Iranian Journal Radiation Res, 2022) Parlar, S.; Var, G.; Cosar, R.; Dogan, M.; Ozguven, Y.; Nurlu, D.; CemUzal, M.
    Background: Cardiac disease is a documented risk factor in left breast irradiation. In an attempt to reduce cardiac toxicity, different treatment techniques adapted to respiratory cycle phases have been developed. The aim of this study is to investigate the feasibility of the voluntary breath hold technique when irradiating the left breast in selected patients. Material and Methods: The study included 20 patients with left sided breast cancer. For each patient, two computed tomography (CT) scans were acquired, one with the free breathing (FB) technique and one with the voluntary deep inspiration breath hold (DIBH) technique. Treatment plans were created using a field-in-field intensity-modulated radiation therapy technique. A dosimetric comparison was made between the two techniques for the heart, left anterior descending (LAD) coronary artery, ipsilateral lung and contralateral breast. Results: The average of the mean dose of the heart decreased from 7.7 Gy to 5.8 Gy and V-20(Gy) (%) from 12.8% to 8.3% using the DIBH technique (p=0.009, p<0.001). The DIBH technique demonstrated significantly smaller maximum heart distance (2.0 cm vs. 0.9 cm, p < 0.001) and 8.0% reduction in LAD mean dose. Furthermore, D-mean for the ipsilateral lung was reduced from 12.8 Gy to 12.2 Gy and V-20(Gy) (%) from 25.6% to 22.8%. Conclusion: In the treatment plans made using the DIBH technique, a significant reduction in the radiation dose delivered to the heart has been observed. In order to reduce long-term morbidity and mortality risks from cardiovascular disease affecting the survival of patients with left sided breast cancer, irradiation techniques such as the DIBH should be considered, especially for premenopausal patients.