Yazar "Mollamahmutoglu, Leyla" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe DIAGNOSTIC VALUE AND TIMING OF SERUM ANTICHLAMIDIAL ANTIBODY LEVEL EVALUATION DURING INFERTILITY WORKUP AMONG INFERTILE WOMEN IN WHOM TUBAL FACTOR WAS DETECTED WITH DIAGNOSTIC LAPAROSCOPY(Galenos Yayincilik, 2012) Kahyaoglu, Serkan; Kahyaoglu, Inci; Sut, Necdet; Aydin, Mehmet; Mollamahmutoglu, Leyla; Ozcan, UtkuObjectives: With normal hysterosalpingography (HSG) results, selecting suitable candidates for the laparoscopic treatment of probable pelvic adhesions following previous pelvic inflammatory disease, it would be wise to investigate serum antibody screening against chlamidia trachomatis. It is worth to evaluate whether it is useful to detect a negative antichlamidial antibody disease for cancelling laparoscopy for a while with abnormal HSG findings. These two subjects have been investigated in study. Material and methods: For detecting diagnostic value of serum antichlamidial antibody, in our infertility clinic, postoperative blood samples of 80 patients who were hospitalized for diagnostic laparoscopy to investigate infertility ethiology between May 2004 and November 2005 have been tested with microelisa method for antichlamidial IgM and IgG antibodies. HSG films of the patients performed at least one year were evaluated. Venous blood was drawn from these patients during postoperative early period for studying serum IgM and IgG antibodies of chlamidia trachomatis and the results were compared with operative findings. Results: According to the antichlamidial antibody levels 60 (75%) patients have not been infected with chlamidia and 20 (25%) patients have been infected previously. When the patients were divided to two groups; normal and abnormal; based on preoperative HSG films; 18 (30%) of the 60 patients with abnormal HSG films and 2 (10%) of the 20 patients with normal HSG films had positive antichlamidial antibody levels respectively. Conclusion: The relationship between chlamidia trachomatis infection and tubal infertility has been demonstrated among 85% of patients with positive antichlamidial antibody levels and 46.7% of patients with negative levels who had tubal passage defects detected during diagnostic laparoscopy.Öğe Meperidine versus valethamate bromide in shortening the duration of active labor(Elsevier Ireland Ltd, 2009) Yilmaz, Bulent; Kart, Cavit; Kelekci, Sefa; Gokturk, Umut; Sut, Necdet; Tarlan, Nurten; Mollamahmutoglu, LeylaObjective: To compare the efficacy and safety of meperidine hydrochloride and valethamate bromide against placebo in shortening the duration of active labor. Method: We randomly assigned 160 nulliparous women with a singleton pregnancy at term who needed induction of labor to one of 3 treatments: 50 mg of meperidine (n = 53), 16 mg of valethamate bromide (n = 53), or a normal saline solution as placebo (n = 54). All medications were given by slow intravenous infusion. Labor duration was the main outcome measure. Results: The intervals between infusion and complete cervical dilation and between infusion and delivery were significantly reduced (P<0.001 and P<0.01) in the meperidine group (103.0 +/- 64.5 minutes and 119.8 +/- 70.2 minutes), in contrast to the placebo group (173.9 +/- 74.8 minutes and 192.2 +/- 82.8 minutes). However, differences were not significant between the 2 treatment groups (139.6 +/- 63.1 minutes and 160.6 +/- 71.9 minutes), or between the valethamate bromide and the placebo group. Conclusion: Meperidine, but not valethamate bromide, significantly shortened the duration of active labor in nulliparous women with a singleton pregnancy at term. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.Öğe Moistening of misoprostol tablets with acetic acid prior to vaginal administration for mid-trimester termination of anomalous pregnancy: A randomised comparison of three regimens(Taylor & Francis Ltd, 2010) Yilmaz, Bulent; Ertas, Ibrahim Egemen; Kelekci, Sefa; Sut, Necdet; Mollamahmutoglu, Leyla; Danisman, NuriMethods A total of 118 women requiring second-trimester pregnancy termination were randomly assigned to one of three treatment groups: 400 mu g 3-hourly in group A (n = 39), 600 mu g 6-hourly in group B (n = 39), and 800 mu g 12-hourly in group C (n = 40). Misoprostol tablets moistened with 3 ml of 5% acetic acid were placed into the posterior vaginal fornix. Results The median induction-abortion times in groups A (8 h [range: 3-64]) and B (9 h [4-81]) were significantly shorter (p < 0.01 and p < 0.05, respectively) than in group C (12.5 [3-72]). Moreover, expulsion rates within 24 hours in groups A (92.3%) and B (92.3%) were significantly higher (p < 0.05 in both cases) than that of group C (75%). Expulsion rate within 48 hours, number of tablets used, number of patients with retained placenta and side effects did not differ between groups. Conclusions Misoprostol moistened with acetic acid is effective for second-trimester pregnancy termination when given vaginally 3-hourly, 6-hourly or 12-hourly. The former two regimens are significantly more effective than the latter.Öğe The Role of Vaginal pH on Efficacy of Controlled-Release Dinoprostone Vaginal Insert for Cervical Ripening/Labor Induction: A Prospective Double-Blind Study(Galenos Yayincilik, 2008) Onen, Fiahin; Ozaksit, Gulnur; Yilmaz, Bulent; Gungor, Tayfun; Bilge, Umit; Sut, Necdet; Mollamahmutoglu, LeylaObjective: To evaluate if vaginal pH has any effect on the efficacy of controlled-release PGE 2 vaginal insert for cervical ripening/labor induction in post-term patients. Materials and Methods: Sixty-three post-term women with unfavorable cervix (Bishop's score +/- 6) undergoing labor induction were enrolled in this prospective, double-blinded trial. All patients received sustained-release dinoprostone vaginal insert for cervical ripening/labor induction during 12 hours, repeated dosing one time 24 hours later. Results: Women with a low vaginal pH (>4.5, n= 38) and women with a high vaginal pH (> 4.5, n= 25) were similar in maternal age, parity, body mass index, gestational age or initial Bishop's score. Bishop's score change over the initial 12 hours significantly (p<0.05) differed between the low vaginal pH (3.9 +/- 3.3) and the high vaginal pH group (5.5 +/- 3.4). Time to active labor (14.7 +/- 17.3 hrs vs 13.1 +/- 9.8 hrs), complete dilation (19.6 +/- 20.1 hrs vs 17.1 +/- 11.8 hrs) and delivery (20.0 +/- 21.4 hrs vs 17.6 +/- 12.0 hrs) were comparable between the low and high vaginal pH groups, respectively. Linear regression analysis revealed no significant association between vaginal pH and Bishop's score change over 12 hours, time to active labor, time to complete dilation, or time to delivery. Discussion: Vaginal pH has significant effect on cervical ripening but has no effect on delivery outcomes in post-term patients with unfavorable cervices, who undergo cervical priming/labor induction using sustained-release dinoprostone vaginal insert.