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Öğe Cardiopulmonary responses to exercise in moderate-to-severe obstructive sleep apnea(Turkish Assoc Tuberculosis & Thorax, 2005) Ozturk, Levent; Metin, Gokhan; Cuhadaroglu, Caglar; Utkusavas, Ayfer; Tutluoglu, BulentInformation regarding the safety of maximal cardiopulmonary exercise testing (CPET) or the mechanisms of exercise limitation in obstructive sleep apnea (OSA) patients is fairly limited. In the present study, we addressed the problem of exercise capacity in moderate-to-severe OSA patients. Nineteen non-consecutive patients (three female, 16 male) with moderate-to-severe OSA and 11 age and body mass index matched control subjects (four female, seven male) underwent respiratory function tests during pre-exercise resting period and volitionally limited cardiopulmonary exercise testing on an electronically braked cycle ergometer. All participants completed CPET without any complication. Control subjects were exercise limited due to deconditioning. None of the patients revealed mechanical ventilatory limitation to exercise or had evidence of cardiac ischaemia. Five patients had no limitation to exercise. Six patients had low VO2peak, low anaerobic treshold (AT), and low peak O-2 pulse, a pattern consistent with ventricular dysfunction. Six patients had low VO2peak, low AT, and peak heart rate less than 85% predicted. This pattern is consistent with exercise limitation due to peripheral vascular disease. Two patients had low VO2peak, low AT without peak oxygen pulse and peak heart rate abnormalities consistent with deconditioning. We concluded that moderate-to-severe OSA patients have impaired exercise capacity. Exercise limitation seems to originate from cardiovascular reasons namely left ventricular dysfunction and/or peripheral vascular impairment; and finally, maximal CPET can be tolerated by these patient group without serious complications.Öğe Effects of Smoking Cessation on Physical Exercise Capacity(Aves, 2005) Metin, Gokhan; Yucel, Rofat; Altan, Mehmet; Ozturk, Levent; Tutluoglu, BulentExercise has been recommended as an adjunct method for smoking cessation. From this point of view, performing exercise tests is becoming increasingly important for determining cardiopulmonary risk factors which individuals carry, for prescribing adequate exercise regimes, and for objectively measuring changes in physical capacity during abstinence period. In this study, we aimed to investigate short term changes in cardiopulmonary exercise capacity of individuals that stop smoking. Thirty-nine (25F/14M) asymptomatic volunteers were recruited from Stop Smoking Clinics, Department of Chest Diseases, Cerrahpasa Faculty of Medicine, Istanbul University. Participants underwent maximal cardiopulmonary exercise testing (CPET) on a cycle ergometer by 20 watt/2 min increases until reaching 85% of age-pre-dicted maximal heart rate. CPET was performed in the 1st and 10th weeks of abstinence period. Gas analyses (VO2 and VCO2) were made using expiration air. Prior to CPET, resting lung function tests were performed for each participant. In the whole group, body weight and body mass index increased (p< 0.01; p< 0.01). Maximal oxygen consumption (VO2max), exercise duration, and work performed by the participants also increased ( p< 0.01; p< 0.001; p< 0.001). In conclusion, smokers well-tolerated cardiopulmonary exercise test without any complications. Aerobic performance parameters of smokers improved significantly in an abstinence period of even as short as 10 weeks.Öğe Pathological processes affecting exercise capacity(Aves, 2007) Metin, Gokhan; Altan, Mehmet; Ozturk, LeventExercise capacity and physical activity status are well-known predictors of general mortality and especially cardiovascular mortality. Pathological processes which may affect exercise capacity may be of cardiovascular, pulmonary, hematologic, myogenic and neuropsychogenic origin. Whatever the reason, reduced exercise capacity impairs quality of life and increases tendency of individual to secondary diseases. These pathologies, alone or together, limit exercise capacity resulting in dyspneoea, pain and fatigue by causing defects in processes involved in oxygen and carbondioxide gases. In this review, pathological processes that impact exercise capacity will be discussed in a systematic manner and uncommon application areas of exercise tests will be mentioned.Öğe Regular Aerobic Training Combined with Range of Motion Exercises in Juvenile Idiopathic Arthritis(Hindawi Ltd, 2014) Apti, Mine Dogru; Kasapcopur, Ozgur; Mengi, Murat; Ozturk, Gulnur; Metin, GokhanObjective. To assess the effects of regular aerobic training combined with range of motion (ROM) exercises on aerobic capacity, quality of life, and function in children with juvenile idiopathic arthritis (JIA). Methods. Thirty patients with JIA and 20 healthy age- matched controls (mean age +/- SD, 11.3 +/- 2.4 versus 11.0 +/- 2.3, resp.;.. > 0.05) were included. All patients performed aerobic walking (4 days a week for 8 weeks) and active and passive ROMexercises of involved joints. All patients completed the childhood health assessment questionnaire (CHAQ) and the child health questionnaire. ROM measurements of joints were performed by using universal goniometer. Aerobic capacity was determined by measuring peak oxygen uptake (VO2peak) during an incremental treadmill test. Results. Peak oxygen uptake and exercise duration were significantly lower in JIA group than in controls (32.5 +/- 6.6 versus 35.9 +/- 5.8 and 13.9 +/- 1.9 versus 15.0 +/- 2.0, resp.; < 0.05 for both). Eight- week combined exercise program significantly improved exercise parameters of JIA patients (baseline versus postexercise VO2peak and exercise duration, 32.5 +/- 6.6 to 35.3 +/- 7.9 and 13.9 +/- 1.9 to 16.3 +/- 2.2, resp.;.. < 0.001 for both). Exercise intervention significantly improved CHAQ scores in JIA patients (0.77 +/- 0.61 to 0.20 +/- 0.28, P < 0.001). Conclusion. We suggest that regular aerobic exercise combined with ROM exercises may be an important part of treatment in patients with JIA.
