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    Pt(II) complex of Schiff base derived from L-phenylalanine and furfuraldehyde in the presence of 8-hydroxyquinoline: Structural analysis, composition of complex and biological activity
    (Centre Mersenne Pour Ldition Scientifique Ouverte, 2020) Altun, Ozlen; Kocer, Melike Ozge
    In the present study, we synthesized a Schiff base (L-1) derived from L-phenylalanine with furfuraldehyde and its Pt(II) complex ([Pt(L-1) (L-2)]: [Pt(N-(furfuralidene)phenylalanine) (8-hydroxyquinoline)]) in the presence of 8-hydroxyquinoline (L-2). The chemical structures of the synthesized Schiff base and Pt(II) complex were characterized using ESI-MS, UV-Visible, FT-IR, H-1 NMR, C-13 NMR, and powder-XRD spectroscopy. The surface morphologies and elemental composition were determined by SEM and EDX. Thermal analysis was performed with TG-DTA. Mole ratio of Meyer and Job methods were used for the composition of complexes. According to these methods, the ratio [Pt2+] : [L-1 + L-2] was found to be 1 : 1. In addition, the antimicrobial activities of L-1 and the complex showed that the compounds have significant antibacterial and antifungal properties. They also show important cytotoxic effects against the growth of mouse embryo fibroblasts (MEF) and human prostate adenocarcinoma (Du145) cancer cells. L-1, L-2, and the Pt(II) complex also displayed effective antioxidant activity.
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    Spectral, kinetic and thermodynamic studies of Pd (II) with Schiff base derived from L-asparagine and furfuraldehyde in the presence of 8-hydroxyquinoline
    (Elsevier, 2021) Altun, Ozlen; Kocer, Melike Ozge
    In this study, a Pd (II) complex of the type [Pd(L-1)(L-2)] (where L-1 : Schiff base derived from L-asparagine and furfuraldehyde; L-2 : 8-hydoxyquinoline) was synthesized and characterised using elemental analysis, magnetic moment, conductivity, ESI-MS, UV-Visible, FT-IR, (1) H NMR, C-13 NMR, XRD, SEM, EDX, and TGDTA. The reaction conditions were determined as pH 7 and lambda = 465 nm. When the reaction kinetics were examined, the rate formula was found to be v = k [Pd-2+][L-1 ](1/2)[L-2](1/2) and k = 2.51 x 10(-3) lmol(-1)s(-1). The activation energy (E-a) and Arrhenius constant (A) were calculated from the Arrhenius equation as 3.107 kJmol(-1) and 5.38 x 10(-5) s(-1), respectively. Thermodynamic parameters, enthalpy, Delta H (kJmol(-1)), entropy, Delta S (Jmol(-1) ), Gibbs free energy, AG (kJmol(-1)) and equilibrium constant, K-e, were determined at temperatures of 293.2, 313.2, 333.2 and 353.2 K. According to the thermodynamic parameters, the reaction was a non-spontaneous process. In addition, catalytic ability of the complex was investigated and it was observed that the complex could effectively catalyse epoxidation of cis-1,2-diphenylethylene with meta-chloroperoxybenzoic acid. (c) 2020 Elsevier B.V. All rights reserved.