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    Cutaneous Burn Wound caused by Liquid Ammonia: Case Report
    (Emergency Medicine Physicians Assoc Turkey, 2010) Kiyak, Medeni Volkan; Sayhan, Mustafa Burak; Kavalci, Cemil; Kopal, Can; Unaldi, Mehmet
    Ammonia related injuries are rarely seen but they are associated with high morbidity and mortality. Liquid ammonia burns the skin through a freezing mechanism, a thermal mechanism, and an alkali burn as well. The burn associated with liquid ammonia is multifactorial. In this case report we aimed to point out the pathophysiology and treatment of cutaneous burn wound caused by liquid ammonia.
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    A Giant Lipoma: A Case Report
    (Emergency Medicine Physicians Assoc Turkey, 2010) Kiyak, Medeni Volkan; Kopal, Can; Sayhan, Mustafa Burak; Kavalci, Cemil
    Lipoma is the most common mesenchymal neoplasm in the human body. They may rarely become giant masses due to their asymptomatic nature. Differential diagnosis includes many malignant and benign tumors. Total surgical excision is the preferred treatment modality. The average age of affected patients is fifth decade of life. It is 5-10 times more common in males. In this case report, we report a 66 years old male with a giant back mass with a diameter of 20 cm and diagnosed as lipoma after its removal and histopathological examination, and reviewed the literature.
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    Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving Injuries
    (Kare Publ, 2020) Yuce, Erkan; Sevim, Kamuran Zeynep; Kiyak, Medeni Volkan; Yildiz, Kemalettin; Dagdelen, Daghan; Irmak, Fatih; Karsidag, Semra
    Objectives: Degloving hand injuries have generally been viewed as among the most difficult of injuries to manage due to the extensive nature of associated damage. The traditional approach to the circumferentially degloved segment of problematic flap viability has been to resuture the flap and to wait and see. However, the waiting period or the specific hemorheological protocol remains uncertain. This study aims to acknowledge if Sivelestat, known to ameliorate ischemia-reperfusion injury, enhances the survival of avulsed flaps in a hind limb degloving model of rats and to compare Sivelestat's effects to Pentoxifylline. Methods: In this study, total flap area (cm2), area of necrosis in the flap (cm(2)), and the ratio between the necrotic and total areas (percentage) were determined. Angiogenesis among the groups was documented with CD31, anti-PECAM staining. TUNEL assay was performed to allow the visualization of cell nuclei containing fragmented DNA, a typical feature of apoptosis. Results: The findings obtained in this study showed that Sivelestat administered at 10 mg/kg/hour dosage will inhibit the ischemia-reperfusion injury more pertinently than Pentoxifylline, which exerts only hemorheological effects. Conclusion: The anti-inflammatory effects of Sivelestat will be beneficial for decreasing the early complications of degloving injury, such as inflammation, sepsis, and edema, better than Pentoxifylline, which exerts only hemorheological effects.