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    Obesity Associated With Active, But Preserved Joints in Rheumatoid Arthritis: Results From our National Registry
    (Turkish League Against Rheumatism, 2016) Ayhan, Fikriye Figen; Ataman, Sebnem; Rezvani, Aylin; Paker, Nurdan; Tastekin, Nurettin; Kaya, Taciser; Bodur, Hatice
    Objectives: This study aims to investigate the prevalence of obesity in patients with rheumatoid arthritis (RA) and associations with disease outcomes. Patients and methods: The study population comprised of 1,038 patients with RA (198 males, 840 females; mean age 56.1 +/- 12.6 years; range 19 to 94 years) who had been included in National RA-Registry. RA disease activity measures, physical function, quality of life, joint destruction, laboratory tests, as well as pain, fatigue, general health, and patient and physician global health assessments on a visual analog scale were collected. Results: Our patients had established RA with mean disease duration of 10.2 +/- 8.8 years and moderate disease activity (disease activity score in 28 joints: mean 3.7 +/- 1.6). According to the body mass index (BMI), 70% of the patients were overweight (n= 362, 34.9%) or obese (n= 364, 35.1%). These patients had higher disease activity scores in 28 joints, visual analog scale-pain and visual analog scale-patient global scores, and higher levels of fasting blood glucose; however, they had lower radiographic scores than normal-BMI patients (p< 0.05). Regression analyses showed that the BMI was independently and inversely associated with disease activity scores in 28 joints and Sharp/van der Heijde scores after the adjustments for biologic and treatment-related factors (p< 0.05). Conclusion: Our findings indicate that obesity is more common in patients with RA than the general population. High disease activity and low radiographic damage were associated with high BMI in this National RA-Registry.
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    Turkish League Against Rheumatism National Recommendations for the Management of Ankylosing Spondylitis
    (Turkish League Against Rheumatism, 2011) Bodur, Hatice; Sivas, Filiz; Yilmaz, Ozlem; Ozgocmen, Salih; Gunaydin, Rezzan; Kaya, Taciser; Ataman, Sebnem
    Objectives: To develop Turkish League Against Rheumatism (TLAR) National Recommendations for the management of ankylosing spondylitis (AS). Materials and methods: A scientific committee of 25 experts consisting of six rheumatologists and 19 physical medicine and rehabilitation specialists was formed by TLAR. Recommendations were based on the 2006 ASsessment in Ankylosing Spondylitis International Working Group(ASAS)/European League Against Rheumatism (EULAR) recommendations and a systematic review of associated publications between January 2005 and September 2010. A Delphi process was used to develop the recommendations. Twelve major recommendations were constructed for the management of AS. Voting using a numerical rating scale assessed the strength of each recommendation. Results: The 12 recommendations include patient assessment, patient follow-up along with pharmacological and non-pharmacological methods. Some minor additions and changes have been made to the ASAS/EULAR recommendations. All of the recommendations had sufficient strength. Conclusion: National recommendations for the management of AS were developed based on scientific evidence and consensus expert opinion. These recommendations will be updated regularly in accordance with recent developments.