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Mediterranean Spotted Fever: Report of Two Cases
(Ortadogu Ad Pres & Publ Co, 2011) Engin, Derya Ozturk; Kuloglu, Figen; Inan, Asuman Sengoz; Ceran, Nurgul; Cakar, Sule; Goktas, Pasa
Mediterranean spotted fever (MSF) is an endemic disease that is caused by R.conorii and spreads with tick bite. Two cases with high fever, headache, muscle pain, extensive maculopapular rash involving palms and soles have been followed up in our clinic in July and August 2008. The first case had tache noire on his leg. Hepatosplenomegaly was detected in the second case. Leukocyte counts were within normal limits while AST, ALT, LDH and CK levels were increased. BUN and creatinin levels were elevated in the second case. Both cases were considered as MSF based on epidemiological and clinical features and treated with doxycycline. Antibodies against to Rickettsiae were positive with immunoflorescence assay in the sera of both patients. Skin biopsy material was found positive in the first case for R.conorii with polymerase chain reaction method. Both cases were discharged without any complications.