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Öğe ASSESSMENT OF TEN-YEAR-LONG RESULTS OF KIDNEY BIOPSIES PERFORMED ON CHILDREN IN THE THRACE REGION OF TURKEY(Springer, 2015) Ozkayin, Nese; Ciplak, Gokce; Usta, Ufuk; Genchellac, Hakan; Temizoz, Osman[Abstract Not Available]Öğe Brain atrophy and hypomyelination associated with Iatrogenic cushing syndrome in an infant(Iranian Child Neurology Soc, 2018) Dogan, Sumeyra; Dogan, Mehmet S.; Tutunculer, Filiz; Yapiciugurlar, Ozge; Genchellac, HakanProlonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.Öğe Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant(Iranian Child Neurology Soc, 2018) Dogan, Sumeyra; Dogan, Mehmet S.; Tutunculer, Filiz; Yapiciugurlar, Ozge; Genchellac, HakanProlonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.Öğe A case of gastric adenocarcinoma with rectal metastasis in the form of linitis plastica presenting as primary rectum carcinoma(Aves Yayincilik, Ibrahim Kara, 2008) Uzunoglu, Sernaz; Cicin, Irfan; Karagol, Hakan; Tanriverdi, Oezguer; Genchellac, Hakan; Usta, UfukIt is often reported that metastases in the form of linitis plastica developed in the gastrointestinal system are rare cases and frequently the primary tumor is located in the stomach. We presented a case of gastric adenocarcinoma developing a metastasis in the rectum in the form of linitis plastica, which appeared as a primary local advanced rectum cancer. We discussed the clinical, radiological, and pathological characteristics of the intestinal metastases of gastric adenocarcinomas.Öğe Computed Tomographic and Magnetic Resonance Imaging Findings of Asymptomatic Intra-Abdominal Gastrointestinal System Lipomas(Lippincott Williams & Wilkins, 2008) Genchellac, Hakan; Demir, Mustafa K.; Ozdemir, Huseyin; Unlu, Ercument; Temizoz, OsmanLipomas are common benign mesenchymal neoplasms documented in literature. This study aimed to describe the computed tomographic (CT) and magnetic resonance imaging (MRI) findings of gastrointestinal system lipomas, all of which are incidentally found in routine abdominal imaging studies. Lipomas were depicted as homogeneous, nonenhancing, well-marginated lesions consistent with adipose tissue on CT and MRI The density measurements on CT images consistent with fat are virtually diagnostic. Lipomas can incidentally be found and should be considered in the differential diagnosis of soft tissue gastrointestinal system-related masses. Computed tomographic or MRI examinations can correctly diagnose a lipoma nonoperatively, thereby allowing better treatment planning..Öğe Contrast-enhanced MR 3D angiography in the assessment of brain AVMs(Elsevier Ireland Ltd, 2006) Unlu, Ercument; Temizoz, Osman; Albayram, Sait; Genchellac, Hakan; Hamamcioglu, M. Kemal; Kurt, Imran; Demir, M. KemalBackground and purpose: Digital subtraction angiography (DSA) is the current reference standard for the diagnosis, assessment, and management of brain arteriovenous malformations (AVMs). The purpose of this study was to compare the diagnostic utility of three-dimensional (3D) time-off-light (TOF) magnetic resonance angiography (MRA) and contrast-enhanced 3D MRA in patients with intracranial arteriovenous malformations (AVMs) in different sizes and locations. The AVM diagnosis was proved via DSA and almost half of the patients had also hematoma. Materials and methods: Two radiologists, experienced on neurovascular imaging and independent from each other, retrospectively reviewed two MRA techniques and DSA with regard to the assessment of feeding arteries, AVM nidus, and venous drainage patterns on 20 patients with 23 examinations by scoring system. Disagreements were resolved by consensus. Results: An excellent agreement between contrast-enhanced MRA and DSA was found in order to assess the numbers of arterial feeders and draining veins (Spearman r=0.913, P<0.001). The average scores in contrast-enhanced MRA for feeders, nidi, and drainers were respectively 2.26, 2.69, and 2.48, while in TOF-MRA they are 1.96, 1.35, and 0.89, respectively. Conclusion: Compared to TOF-MRA, 3D contrast-enhanced MRA is useful for visualization by subtraction technique of malformation components presented by hematoma or by haem product. On the other hand, for the cases presented by slow or complex flow that is especially in around or nidi or around the venous portion is also advantageous because of the independence from flow-related enhancement. Therapeutic effects were clearly demonstrated in three follow-up patients. A major limitation of this technique is the low spatial resolution. Since there is such a limitation, arterial feeder of a case with micro-AVM is not detected by contrast-enhanced MRA and nidus for the same case was observed retrospectively. In this respect, we believe that 3D contrast-enhanced MRA is a less invasive and inexpensive angiographic tool, but not a safe substitute for DSA. Yet, it can be a beneficial supplement to DSA in patients with cerebral AVMs at both initial diagnosis and at follow-up processes after therapy. (C) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe CT-angiographic demonstration of hepatic collateral pathways due to superior vena cava obstruction in Behcet disease(Turkish Soc Radiology, 2010) Temizoz, Osman; Genchellac, Hakan; Yekeler, Ensar; Demir, Mustafa Kemal; Unlu, Ercument; Ozdemir, HuseyinBehcet disease (BD) is a chronic multisystemic inflammatory disorder, mainly characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. Large vein thrombosis in BD is unusual; when present, it is most frequently seen in the inferior or superior vena cava (SVC). The authors describe an unusual hepatic pseudolesion caused by abnormal focal enhancement through collateral pathways to the liver in two BD patients with SVC occlusion on three-dimensional multi-detector computed tomography, using volume rendering and maximum intensity projection techniques. BD should be suspected in patients presenting a focal increased hepatic enhancement area with collaterals caused by occlusion of the SVC without evidence of a hypercoagulable state or malignant mediastinal or thoracic venous inlet obstruction.Öğe Differential diagnosis of spinal epidural meningioma and hemangioma at MR imaging(Radiological Soc North America, 2007) Demir, Mustafa Kemal; Ozdemir, Huseyin; Unlu, Ercument; Temizoez, Osman; Genchellac, Hakan[Abstract Not Available]Öğe Digital subtraction angiography of a persistent trigeminal artery variant(Aves, 2010) Temizoz, Osman; Genchellac, Hakan; Unlu, Ercuement; Cagli, Bekir; Ozdemir, Hueseyin; Demir, M. KemalPersistent trigeminal artery variants are described as cerebellar arteries that directly originate from the precavernous segment of the internal carotid artery. This has been observed in 0.18% of cerebral catheter angiograms. On the other hand, a persistent trigeminal artery variant feeding both the anterior inferior cerebellar artery and the posterior inferior cerebellar artery territory is very rare. We present this uncommon anomalous artery along with digital subtraction angiography findings and discuss its clinical significance in light of the literature.Öğe Dural sinus vein thrombosis in a patient with colon cancer treated with FOLFIRI/bevacizumab(Wolters Kluwer Medknow Publications, 2009) Ozen, Alaattin; Cicin, Irfan; Sezer, Atakan; Uzunoglu, Sernaz; Saynak, Mert; Genchellac, Hakan; Karagol, HakanThe adverse effects of regimes in cancer treatment have forced us to change to new targeted therapy options. Understanding these side effects, which can lead to discontinuation of the new therapy strategies, will allow the clinical management of these side effects and result in continuing therapies with effective medications. Bevacizumab, which is an IgG1 antibody against vascular endothelial growth factor, has side effects such as proteinuria, hypertension, venous and arterial thromboembolic events, and hemorrhage. This is the first reported case of dural sinus vein thrombosis, during the treatment with bevacizumab.Öğe Extraspinal Incidental Findings on Routine MRI of Lumbar Spine: Prevalence and Reporting Rates in 1278 Patients(Korean Radiological Soc, 2015) Tuncel, Sedat Alpaslan; Cagli, Bekir; Tekatas, Aslan; Kirici, Mehmet Yadigar; Unlu, Ercument; Genchellac, HakanObjective: The aim of the present study was to determine the prevalence and reporting rate of incidental findings (IF) in adult outpatients undergoing lumbar magnetic resonance imaging (MRI). Materials and Methods: Re-evaluation of a total of 1278 Lumbar MRI images (collected from patients with a mean age of 50.5 years, range 16-91 years) captured between August 2010-August 2011 was done by a neuroradiologist and a musculoskeletal radiologist. IFs were classified according to organ or system (liver, gallbladder, kidney, bladder, uterus, ovary, lymph node, intestine and aorta). The rate of reporting of a range of IF was examined. The outcome of each patient's treatment was evaluated based on review of hospital records and by telephone interviews. Results: A total of 253 IFs were found in 241 patients (18.8% of 1278). Among these, clinically significant IFs (n = 34) included: 2 renal masses (0.15%), 2 aortic aneurysms (0.15%), 2 cases of hydronephrosis (0.15%), 11 adrenal masses (0.86%), 7 lymphadenopathies (0.55%), 6 cases of endometrial or cervical thickening (0.47%), 1 liver hemangioma (0.08%), 1 pelvic fluid (0.08%) and 2 ovarian dermoid cysts (0.15%). Overall, 28% (71/253) of IFs were included in the clinical reports, while clinically significant findings were reported in 41% (14/34) of cases. Conclusion: Extraspinal IFs are commonly detected during a routine lumbar MRI, and many of these findings are not clinically significant. However, IFs including clinically important findings are occasionally omitted from formal radiological reports.Öğe Hepatic pseudolesion around the falciform ligament: Prevalence, aberrant venous supply, and fatty infiltration evaluated by multidetector computed tomography and magnetic resonance imaging(Lippincott Williams & Wilkins, 2007) Genchellac, Hakan; Yilmaz, Sabri; Ucar, Adem; Dursun, Memduh; Demir, Mustafa Kemal; Yekeler, EnsarPurpose: The aim of this study was to determine the prevalence and aberrant venous supply (inferior veins of Sappey) of hypoattenuating hepatic pseudolesions seen around the falciform ligament on portal-dominant phase multidetector computed tomography (MDCT) and the frequency of fatty infiltration of these pseudolesions on chemical-shift magnetic resonance imaging. Materials and Methods: Portal-dominant phase abdominal MDCT examinations of 728 patients were evaluated for the presence of a pseudolesion around the falciform ligament, and those with a presumed pseudolesion underwent chemical-shift magnetic resonance imaging to detect the fatty infiltration. Reconstructed MDCT images were investigated for the presence of an inferior vein of Sappey, and 30 patients without a pseudolesion were evaluated as a control group. Results: A total of 160 pseudolesions Were detected around the falciform ligament in 146 (20%) patients. The longest diameter of the pseudolesions was in the craniocaudal direction in most patients (61%). An inferior vein of Sappey supplying these pseudolesions was depicted in 40 (27%) patients, and it was highly significant (P = 0.001) compared with the controls for the presence of a pseudolesion around the falciform ligament. Fatty infiltration was found in 47 (29%) patients. Conclusions: Hepatic pseudolesions around the falciform ligament are frequently encountered on portal-dominant phase MDCT images. Detection of craniocaudal extension, inferior veins of Sappey, and fatty infiltration of these pseudolesions, which were firstly described in this article, with the largest subject group based on cross-sectional imaging, might be valuable in excluding true tumors.Öğe Hypothenar hammer syndrome(John Wiley & Sons Inc, 2008) Genchellac, Hakan; Demir, Mustafa Kemal; Unlu, Ercuement; Temizoz, Osman; Ozdemir, HuseyinWe report a case of hypothenar hammer syndrome following a single severe blunt trauma in a 24-year-old man with a painful pulsatile mass, numbness in the fourth and fifth fingers, and intolerance to cold. The gray-scale and color Doppler sonographic findings are presented with correlation with MRI. (C) 2007 Wiley Periodicals, Inc.Öğe Incidental Pancreatic Lipomas: Computed Tomography Imaging Findings with Emphasis on Diagnostic Challenges(Elsevier Science Bv, 2010) Temizoz, Osman; Genchellac, Hakan; Unlu, Ercument; Kantarci, Fatih; Umit, Hasan; Demir, Mustafa KemalPurpose: The purpose of this study was to describe the computed tomography (CT) findings of pancreatic lipomas of 9 cases, with emphasis to diagnostic challenges. Methods: Between March 2006 and April 2008, 9 patients with pancreatic lipomas that were diagnosed by CT were reviewed in the present study. Clinical data and CT features of these 9 cases were retrospectively analysed. The patient population included 5 men and 4 women, aged 42-81 years (mean age, 65.8 years). The patients were followed up for at least 2 years with control CTs. Results: In all 9 cases, a well-bordered nodular fat density lesion was incidentally detected in the pancreas. Four of the lesions had a lobulated contour, and 2 of them had septations. Two of the lipomas were located in the head, 3 in the neck, 3 in the corpus, and 1 in the tail. The CT densitometric values were between -90 and -120 HU, with a mean value of 106 HU. No pancreatic or biliary dilatation or compression to the adjacent structures was seen. All the cases had control CTs, and the lipomas remained unchanged during the follow-up period. Histopathologic confirmation of the diagnosis was not planned for the cases. Conclusion: Lipomas are rarely encountered in the pancreas. They often are diagnosed coincidentally as small, well-circumscribed, encapsulated, homogeneous, mature adipose masses on imaging studies. Imaging follow-up strategy or histopathologic confirmation is not necessary in asymptomatic patients.Öğe A non-alcoholic patient with acute Marchiafava-Bignami disease associated with gynecologic malignancy: Paraneoplastic Marchiafava-Bignami disease?(Elsevier Science Bv, 2007) Celik, Yahya; Temizoz, Osman; Genchellac, Hakan; Cakir, Bilge; Asil, TalipWe report a 45-year-old, non-alcoholic woman with ovarian cancer who presented with acute impairment of consciousness. Cranial MRI revealed symmetrical and bilateral increased signal intensities of the corpus callosum and the dentate nucleus, without contrast enhancement. The findings are comparable with Marchiafava-Bignami disease (MBD), although pathological confirmation was not possible. Most of the reported cases of MBD are related to chronic ingestion of red wine and/or related with a nutritional cause. We suggest that this patient may suffer a MBD possible related to the ovarian cancer. (C) 2007 Elsevier B.V. All fights reserved.Öğe Perineal angiomyxomas: Can a differential diagnosis be made with imaging studies?(Radiological Soc North America (Rsna), 2007) Demir, Mustafa Kemal; Genchellac, Hakan; Ozdemir, Huseyin[Abstract Not Available]Öğe Phase inversion harmonic imaging improves assessment of renal calculi(John Wiley & Sons Inc, 2008) Ozdemir, Huseyin; Demir, Mustafa Kemal; Temizoz, Osman; Genchellac, Hakan; Unlu, ErcumentPurpose. To compare phase inversion harmonic imaging (PIHI) with fundamental imaging (FI) in the evaluation of renal calculi. Methods. Thirty adult patients with renal calculi (17 men, 13 women; mean age 44 years [range, 25-71]) underwent transabdominal sonographic examination of the urinary system. Both kidneys and renal calculi were examined with PIHI and A. Overall renal con picuity, calculus visibility, and clarity of posterior shadowing were assessed subjectively using a 4-point scale (0 being the worst, 3 being the best). The maximum diameter of the calculi was measured using both techniques. The effect of body mass index on qualitative scoring and quantitative measurements was evaluated. Results. PIN improved overall renal conspicuity compared with A (p < 0.001). The visibility of the calculi and clarity of posterior shadowing were significantly better with PIHI than with A (p, < 0.001 for both parameters). The maximum diameter of calculi was larger with PIHI than with FI (p < 0.001). The superiority of PIHI over FI regarding overall conspicuity of the kidney, visibility of the calculus, and clarity of posterior shadowing scores increased in the obese group (p < 0.001 for all 3 parameters). The mean calculus diameter difference between the 2 techniques was significantly higher in the obese group. Conclusion. The routine use of PIHI is recommended in the evaluation of renal calculi. (c) 2007 Wiley Periodicals, Inc.Öğe Prevalence and MDCT characteristics of asymptomatic Bochdalek hernia in adult population(Turkish Soc Radiology, 2010) Temizoz, Osman; Genchellac, Hakan; Yekeler, Ensar; Umit, Hasan; Unlu, Ercument; Ozdemir, Huseyin; Demir, M. KemalPURPOSE To determine the frequency of asymptomatic incidental Bochdalek hernias in adults, using multidetector computed tomography (MDCT), and to ascertain any possible relationship between Bochdalek hernia and age, gender, or body mass index (BMI). MATERIALS AND METHODS Seven hundred and forty-eight abdominal, and 602 chest MDCT scans, which had been performed for a variety of reasons on 1350 adults, were investigated retrospectively. Location and size of Bochdalek hernias seen on these scans were correlated with age, gender, and BMI. On the basis of BMI, patients with Bochdalek hernia were classified as group A (BMI <25) and group B (BMI >= 25). RESULTS A total of 171 Bochdalek hernias were identified in 142 of 1350 patients, ranging in age from 25 to 90 years (median age, 57.2), representing a prevalence of 10.5%. Sixty left-sided unilateral Bochdalek hernias (42.2%), 53 (37.4%) right-sided unilateral Bochdalek hernias, and 29 (20.4%) bilateral Bochdalek hernias were detected. Forty-five (31.6%) were categorized as small, 82 (57.8%) were medium-sized, and 1 5 (10.5%) were large. BMI was <25 in 62 patients (43.7%), and >= 25 in 80 patients (56.3%). Fourteen patients (9.9%) were young adults, while 86 (60.6%) were middle aged, and 42 (29.6%) were elderly. No statistically significant relationship was found between dimensions or hernia locations and age, gender, or BMI of patients with Bochdalek hernia. CONCLUSION In view of the high prevalence of Bochdalek hernia in our study (10.5%), the multiplanar and reconstruction features of MDCT seem to facilitate the diagnosis of asymptomatic incidental Bochdalek hernia. No relationship was found between asymptomatic incidental Bochdalek hernia and age, gender, or BMI in adults.Öğe A Rare Case of Schwannoma Arising From a Diverticulum in the First Portion of Duodenum [Letter](Galenos Publ House, 2012) Genchellac, Hakan; Temizoz, Osman[Abstract Not Available]Öğe The relationship between magnetic resonance Imaging findings and postural Maneuver and physical examination tests in patients with thoracic outlet syndrome: Results of a double-blind, controlled study(W B Saunders Co-Elsevier Inc, 2007) Demirbag, Derya; Unlu, Ercument; Ozdemir, Ferda; Genchellac, Hakan; Temizoz, Osman; Ozdemir, Huseyin; Demir, KemalObjectives: To investigate the differences in findings from magnetic resonance imaging (MRI) in the neutral and provocative positions, and to examine the relationship between these differences and the results of physical examination tests in patients with thoracic outlet syndrome (TOS). Design: Prospective. Setting: University physical medicine and rehabilitation outpatient and radiology clinics. Participants: Twenty-nine patients and 12 healthy controls. All of the patients had positive bilateral TOS stress tests; control group participants were symptom free and had negative TOS stress tests bilaterally. Interventions: Not applicable. Main Outcome Measures: All participants underwent Adson's test, the Halsted maneuver, and a hyperabduction test. All were evaluated with MRI while in 2 positions: the neutral position (upper extremities adducted) and in a provocative position. Measurements were obtained at the interscalene triangle, at the costoclavicular space, and at the retropectoralis minor space. Results: There was a significant difference in MRI findings between the neutral and provocative position in the patient (P<.05), but there were no significant differences in the control group. There was a significant difference in the positional change values in MRI between the patients and the control subjects (P<.05). The difference was found in the minimum costoclavicular distance between patients with a positive Halsted maneuver and a negative Halsted maneuver (P<.05). Conclusions: Our findings indicate that MRI findings in patients in a provocative position are more valuable in the diagnosis of TOS, and these findings are in accord with findings from the physical evaluation tests.