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Öğe Clinical and Histopathological Evaluation of Eyelid Lesions: Retrospective Analysis of Tertiary Medical Center Referrals(Trakya Üniversitesi, 2021) İzzettinoğlu, Mustafa Ömer; Akay, Fatih Erkan; Garip, RüveydeAims: To clinically and histopathologically examine eyelid lesions and evaluate the consistency of clinical examination by comparing the provisional diagnoses of patients with their postoperative histopathology results. Methods: In this study, the records of 408 patients who applied to Trakya University, Department of Ophthalmology with an eyelid mass and underwent surgery between January 2000 to November 2019 were retrospectively analyzed. Patients’ data comprised age, gender, location of the mass, lesion distribution according to age and gender, provisional clinical diagnosis of the patients, and histopathological reports. Results: Out of 408 patients, 220 (54%) were female, and 188 (46%) were male. The mean age of the patients was 46.9 ± 20.17 years (range; 5-90 years). In the histopathological examination of the lesions, 318 (77.9%) of them were benign, and 90 (22.1%) of them were malignant. The most common benign lesion was chalazion [112 (35.2%)], while the most common malignant lesion was basal cell carcinoma [71 (78.9%)]. The clinical pre-diagnosis and histopathological di- agnosis were found to be compatible in 81 (90%) patients with a malignant lesion. There was a statistically significant difference in age between malignant and benign lesions, where malignant lesions were found more in older patients. The histopathological examination ended up being malignant in 2.2% of the lesions with a benign provisional diagnosis. Conclusion: In conclusion, even though most common eyelid lesions in our study were found to be benign, some lesions diagnosed as benign in clinic were found to be malignant after histopathological examination. Hence all excisions should be evaluated histopathologically to achieve a better clinical outcome in all patients with an eyelid lesion.Öğe Evaluation of Macular, Ganglion Cell Complex and Retinal Nerve Fibre Layer Thickness Changes in Preperimetric Glaucomatous Eyes(2022) Sakallıoğlu, Ahmet Kürşad; Gürlü, Vuslat; Garip, Rüveyde; Güçlü, HandePurpose: To investigate macular thickness (MT), ganglion cell complex (GCC), and retinal nerve fiber layer (RNFL) thickness changes in preperimetric glaucoma patients. Materials and Methods: In the present study 105 eyes of 75 patients were investigated. Of these patients, 56 eyes of 45 patients who were diagnosed as preperimetric glaucoma are taken as a study group and 49 eyes of 30 cases without any ocular pathology are taken as the control group. The mean values of central MT, parafoveal MT, perifoveal MT, parafoveal GCC thickness, and perifoveal GCC thickness evaluations using optical coherence tomography (OCT) were compared between the two groups. Peripapillary RNFL measurements; the mean values of the total, superior hemi-central, inferior hemi-central, superior, inferior, nasal, and temporal quadrants, and twelve sectors were compared between the two groups. Results: In the study group, perifoveal GCC thickness was significantly thinner in the superonasal, superotemporal, inferonasal, and inferotemporal quadrants compared to the control group. Peripapillary RNFL thickness was significantly thinner in the study group in total, superior hemi-central, inferior hemi-central, superior, inferior, nasal, temporal, and hour 1,2,3,4,5,7,8,9 quadrants. No significant difference was detected between the two groups in other measurements (p>0.05). Conclusion: However both macular and peripapillary cellular losses have been initiated in cases with preperimetric glaucoma, this loss can not be detected by standard automated perimetry. As a result, perifoveal GCC and peripapillary RNFL measurements by OCT in patients with preperimetric glaucoma are very helpful for diagnosing suspicious cases.Öğe Long-Term Surgical Outcomes of Patients With Phacomorphic Glaucoma(Trakya Üniversitesi, 2021) İzzettinoğlu, Mustafa Ömer; Küpeli Çınar, Ayşe; Garip, RüveydeAims: To retrospectively analyze clinical characteristics of patients diagnosed with phacomorphic glaucoma in the Ophthalmology Department of Trakya University Hospital. Methods: This retrospective cross-sectional study was conducted with patients who were diagnosed with phacomorphic glaucoma in the Ophthalmology Department of Trakya University Hospital between January 2010 and January 2021. Results: Initially, 19 eyes from 19 patients diagnosed with phacomorphic glaucoma met the inclusion criteria. The mean preoperative best-corrected visual acuity was 0.1 ± 0.3 Snellen visual acuity (ranging from 0.001 to 1.0 Snellen visual acuity). A statistically significant increase in postoperative best-corrected visual acuity during the follow-ups has been observed. In terms of intraocular pressure levels, patients had mean preoperative 32.3 ± 11.2 mmHg (range:15-55 mmHg). The decrease in postoperative intraocular pressure levels during follow-ups was statistically significant. Conclusion: Lens removal through phacoemulsification or intracapsular cataract extraction is an effective and safe procedure in the treatment of phacomorphic glaucoma, ensuring a satisfactory long-term intraocular pressure control and a rapid functional recovery. However, most of the patients are expected to have an outcome of favorable best-corrected visual acuity after surgery in the long term.Öğe Outcomes of Inferior Retinectomy in Patients with Recurrent Rhegmatogenous Retinal Detachment due to Proliferative Vitreoretinopathy(2021) Garip, Rüveyde; Özal, Ece; Kaya, Sultan; Özal, Sadık AltanPurpose: The aim of this study was to evaluate and report the complication rates, and anatomical and functional outcomes of eyes undergoing inferior retinectomy for the management of recurrent rhegmatogenous retinal detachment (RRD) due to inferior proliferative vitreoretinopathy (PVR). Materials and Methods: This retrospective, non-comparative, interventional case series was conducted with 32 eyes of 32 patients with recurrent RRD due to inferior PVR who had previously undergone 23-gauge pars plana vitrectomy (PPV) and inferior retinectomy. Demographic data, and preoperative, intraoperative and postoperative characteristics were evaluated from the medical records of the patients. The anatomic and functional success were considered as the primary outcomes. The secondary outcome was the postoperative complications. Results: The mean follow-up time after the PPV with retinectomy was 10.6 ± 4.9 (min. 6, max. 24) months. After the initial retinectomy, anatomic success was achieved in 22 (68.7%) patients. Overall, the retinas of 27 patients (84.4%) were successfully reattached after retinectomy and PPV at the last visit. The mean best-corrected visual acuity (BCVA) improved from 1.72 ± 0.97 LogMar (range, 3.0-0.4 LogMar) to 1.20 ± 0.65 LogMar (range, 3.0-0.3 LogMar) at the fi nal visit. There was a statistically signifi cant increase in visual acuity postoperatively (p = .01). At the last visit, BCVA was improved in 19 eyes (59.4%), stabilized in 8 eyes (25%) and decreased in 5 eyes (15.6%). The most signifi cant factor affecting the fi nal BCVA was the baseline visual acuity (p = .002). Two patients (6.2%) developed hypotonia postoperatively. None of the cases presented with endophthalmitis, keratopathy or postoperative phthisis bulbi. Conclusion: Inferior retinectomy is effective in managing recurrent RRD cases due to inferior PVR and can increase functional success rates.Öğe Retrospective Analysis of the Impacts of Treatment Regimens on the Progression and Prognosis of Diabetic Retinopathy and Visual Acuity in Trakya University School of Medicine(Trakya Üniversitesi, 2021) İzzettinoğlu, Mustafa Ömer; Garip, RüveydeAims: To retrospectively analyze the impacts of treatment regimens on progression and prognosis of diabetic retinopathy and visual acuity in Trakya University Hospital. Methods: This retrospective cross-sectional study was conducted with patients who were diagnosed with diabetic retinopathy in the Ophthalmology Department of Trakya University Hospital between January 2006 and January 2020. Results: Initially, 798 eyes from 399 patients diagnosed with diabetic reti- nopathy met the inclusion criteria. Non-proliferative diabetic retinopathy was present on 202 (50.6%) patients, and 197 (49.4%) patients had proliferative diabet- ic retinopathy. Twenty-five patients (6.2%) had proliferative diabetic retinopathy progression. Patients with proliferative diabetic retinopathy progression had no difference in terms of cataract surgery, gender, and hypertension existence than the ones who did not experience proliferative diabetic retinopathy progression. There was no relation between stability, increase or decrease of visual acuity, the type of diabetes, retinal laser photocoagulation treatment, and the type of in- travitreal injection. Conclusion: Our study showed that retinal laser photocoagulation treatment and cataract surgery had no significant impact on visual acuity prognosis, unlike the initial examination visual acuity values. Additionally, it was also shown that the different types of intravitreal injections made no dissimilar results on visual acuities. In addition, in our study, it was revealed that gender, presence of hypertension, and cataract surgery may not have a significant relation with proliferative diabetic retinopathy progression. Further studies are needed to thoroughly reveal the relation between the treatment regimens, progression, and prognosis of the disease.