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Öğe Bioassay-guided isolation of cytotoxic retrochalcones from Glycyrrhiza echinata L. roots and elucidation of their cell death mechanisms(Georg Thieme Verlag Kg, 2022) Cevik, D.; Erdogan, S.; Serttas, R.; Kan, Y.; Kirmizibekmez, H.[Abstract Not Available]Öğe Chitin Extraction and Chitosan Production from Cell Wall of Two Mushroom Species (Lactarius Vellereus and Phyllophora Ribis)(Amer Inst Physics, 2017) Erdogan, S.; Kaya, M.; Akata, I.Chitin is an important polysaccharide found as supporting material in the cell wall of mushrooms. In this study, chitin and chitosan were obtained from the cell wall of two different mushroom species using chemical method and physicochemically characterized. The dry weight chitin contents of the mushroom species were determined as 11.4% for Lactarius vellereus and 7.9% for Phyllophora ribis. Chitosan yields of the chitins isolated from L. vellereus and P. ribis were 73.1% and 75.3%, respectively. While, the maximum degradation temperatures of vellereus and P. ribis chitins were found to be 354 degrees C and 275 degrees C by thermogravimetric analysis (TGA), the maximum degadation temperature of the chitosans obtained from these chitins were recorded as 262 degrees C and 229 degrees C, respectively. The crystalline index values of L. vellereus and P. ribis chitins were calculated as 64% and 49%, respectively according to the X-ray diffraction analysis (XRD) results. The scanning electron microscopy (SEM) indicated that there were no nanofiber or nanopores on the surface of the chitins and chitosans obtained from these two mushroom species. The results of this study revealed that L. vellereus and P. ribis had higher chitin contents than some other insects and mushroom species recorded in the literature and these species may be used as a potential chitin sources.Öğe Chitin extraction and chitosan production from Chilopoda (Scolopendra cingulata) with identification of physicochemical properties(Maik Nauka/Interperiodica/Springer, 2015) Zelencova, L.; Erdogan, S.; Baran, T.; Kaya, M.The Chilopoda is found in a broad array of terrestrial habitats from tropical rain forests to deserts and there are more than 8000 species worldwide. Chitin and chitosan were obtained from Scolopendra cingulata for the first time in this study and physico-chemically characterized. The dry weight chitin content of S. cingulata was found to be 8% of body weight, and it produced chitosan yields of 66%. Analyses results revealed that Chilopoda chitin was in the alpha-form. The chitosan derived from Chilopoda chitin has a low molecular weight (2.278 kDa). The surface morphology of chitin from S. cingulata consists of dispersed nanopores and nanofibres.Öğe Downregulation of midkine enhances the efficacy of quercetin on androgen-sensitive prostate cancer stem cell survival through arresting cell cycle and inducing apoptosis(Wiley, 2018) Erdogan, S.; Turkekul, K.; Serttas, R.; Doganlar, Z. B.; Doganlar, O.; Dibirdik, I.; Bilir, A.[Abstract Not Available]Öğe Effect of fasudil on the expression of apoptotic proteins in amyloid-beta induced PC12 cells(Wiley-Blackwell, 2016) Eser, B. E.; Kuzudisli, S. Uslu; Oztas, N.; Erdogan, S.; Dogantekin, E.; Demiryurek, T.; Koc, A.[Abstract Not Available]Öğe EFFICIENCY OF DIRECT ORAL ANTICOAGULANTS ON ANTIPHOSPHOLIPID ANTIBODY SYNDROME: A CASE REPORT(Pergamon-Elsevier Science Ltd, 2016) Maden, M.; Umit, E. G.; Erdogan, S.; Demir, A. M.[Abstract Not Available]Öğe The flavonoid apigenin reduces survival and migration of CD44+prostate cancer stem cells(Wiley-Blackwell, 2016) Erdogan, S.; Doganlar, O.; Doganlar, Z. B.; Serttas, R.; Turkekul, K.; Dibirdik, I.; Bilir, A.[Abstract Not Available]Öğe Glycyrrhiza glabra protects the liver hepatocytes from the volatile organic compounds(Elsevier Ireland Ltd, 2016) Erdogan, Z.; Erdogan, S.; Doganlar, Z. B.; Doganlar, O.; Canogullari, S.[Abstract Not Available]Öğe Helminth parasites of digestive tract of some teleost fish caught in the Dardanelles at Canakkale, Turkey(Walter De Gruyter Gmbh, 2007) Keser, R.; Bray, R. A.; Oguz, M. C.; Celen, S.; Erdogan, S.; Doguturk, S.; Aklanoglu, G.In this study the following parasites were found in fishes from the Dardanelles at Canakkale: Cestoda: Bothriocephalus scorpii, Grillotia sp. and Scolex pleuronectis in Solea solea; Digenea: Ectenurus lepidus, Prodistomum polonii and Monascus filiformis in Trachurus trachurus, Hemiuridae metacercaria in S. solea, Lecithocladium excisum in Scomber scombrus, Lecithostaphylus retroflexus in Belone belone, Opechona bacillaris in Pomatomus saltatrix and S. scombrus and Schikhobalotrema sparisomae in Liza saliens; Nematoda: Hysterothylacium aduncum in T. trachurus, S. solea, Sparus aurata, P. saltatrix, L. saliens and Engraulis encrasicolus and Anisakis simplex in S. scombrus; Acanthocephala: Neoechinorynchus agilis in L. saliens. No parasites were recovered from Sardinella aurita. Most of these species are well known in both the Mediterranean and Black Seas, but the Dardanelles appears to be the limit of the range of Anisakis simplex.Öğe Myricetin induces apoptosis in HeLa cells: A time and dose dependent study(Elsevier Ireland Ltd, 2016) Tabakcioglu, K.; Doganlar, Z. B.; Doganlar, O.; Erdogan, S.; Ongoren, G.[Abstract Not Available]
