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    Brain atrophy and hypomyelination associated with Iatrogenic cushing syndrome in an infant
    (Iranian Child Neurology Soc, 2018) Dogan, Sumeyra; Dogan, Mehmet S.; Tutunculer, Filiz; Yapiciugurlar, Ozge; Genchellac, Hakan
    Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.
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    Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
    (Iranian Child Neurology Soc, 2018) Dogan, Sumeyra; Dogan, Mehmet S.; Tutunculer, Filiz; Yapiciugurlar, Ozge; Genchellac, Hakan
    Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.
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    Evaluation of symmetrical increased echogenicity of bilateral caudothalamic grooves detected on cranial ultrasonography by comparing with susceptibility-weighted imaging
    (Springer-Verlag Italia Srl, 2018) Dogan, Mehmet S.; Koc, Gonca; Doganay, Selim; Dogan, Sumeyra; Ozdemir, Ahmet; Korkmaz, Levent; Coskun, Abdulhakim
    To assess symmetrical increased echogenicity of bilateral caudothalamic grooves (SIEBCG) detected on newborn cranial ultrasonography (CUS) using magnetic resonance susceptibility-weighted imaging (SWI). A total of 14 newborns (8 girls; 12 premature with mean gestational age of 30 weeks and 5 days, 2 mature) who were detected to have SIEBCG on routine serial CUS and underwent cranial magnetic resonance imaging (MRI) were recruited for the study. The cranial MRI examinations including SWI acquired on the same day of SIEBCG detection and serial CUS to assess the progress of SIEBCG lesions in the following 6 month period were retrospectively evaluated and compared for the presence of germinal matrix hemorrhage. On SWI, solely one patient (7, 1%) had signal alteration on caudothalamic groove compatible with grade 1 germinal matrix hemorrhage. Two patients (14, 2%) had parenchymal (on cerebellar and parietal white matter) millimetric hemorrhagic foci. Seven patients (50%) had signs of presumptive hypoxic insult including hyperintense dots on centrum semiovale and periventricular white matter in five, and increased signal intensity on the globus pallidi in two, on T1-weighted images. Four patients (28, 6%) had normal findings. Of these, 10 patients became normal on follow-up CUS at postterm-equivalent age, whereas four were missing. Symmetrical increased echogenicity of bilateral caudothalamic grooves seen on newborn CUS may be the indicator of other pathologies as ischemic insult or focal parenchymal hemorrhage. In the presence of SIEBCG, further examination with SWI should be performed.
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    Immature Cystic Teratoma Filling the Spinal Column
    (Springer India, 2016) Dogan, Sumeyra; Dogan, Mehmet S.; Doganay, Selim; Koc, Gonca; Gorkem, Sureyya B.; Coskun, Abdulhakim
    [Abstract Not Available]
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    Rapidly growing cervical teratoma - fetal death during delivery
    (Hygeia Press Corridori Marinella, 2017) Cilingir, Isil Uzun; Sayin, N. Cenk; Erzincan, Selen Gursoy; Inan, Cihan; Sutcu, Havva; Dogan, Sumeyra; Can, Nuray
    Here we present a rapidly growing fetal cervical teratoma associated with agenesis of the corpus callosum that caused an early delivery resulting in rupture of the mass and neonatal death during Cesarean section. Large cervical lesions may threaten the life of the fetus during delivery of the head.