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Öğe Investigation of the Effects of Different Intraabdominal Pressures on Optic Nerve Sheath Diameter in Patients Undergoing Major Abdominal Surgery(Springer India, 2022) Inal, Mehmet Turan; Memis, Dilek; Demir, Emin Tunc; Arslan, Ismail; Korkmaz, SelcukIncreased intraabdominal pressure (IAP) has deleterious effects on intracranial pressure. In this study, we intended to investigate the effects of intraabdominal pressure values on intracranial pressure (ICP) measured by ultrasound-assisted optic nerve sheath diameter (ONSD) measurement in patients who underwent major surgery. Observational study. All patients' age, gender, weight, types of surgeries, comorbidities, Acute Physiology and Chronic Health Evaluation (APACHE) score, Sequential Organ Failure Assessment (SOFA) score, operation time, and amount of fluid administered during the operation were all recorded. Intraabdominal pressure and optic nerve sheath diameter measurements were measured. The patients were separated into 3 groups: group I, intraabdominal pressure 0-11 mmHg; group II, intraabdominal pressure 12-19 mmHg; and group III, intraabdominal pressure 20 mmHg and above. Intensive care unit (ICU) stay and prognosis were all recorded. Intraabdominal pressure, left optic nerve sheath diameter, right optic nerve sheath diameter, and heart rate (HR) measurements were meaningfully higher in group II and group III compared to group I (p < 0.001 for each), and group III was significantly higher compared to group I (p < 0.001). In patients with high intraabdominal pressure, optic nerve sheath diameter follow-up with ultrasonography gains great importance. We recommend that attention should be paid to this situation.Öğe Pulmonary effects of ozone therapy at different doses combined with antibioticotherapy in experimental sepsis model(Acta Cirurgica Brasileira, 2020) Kapicibasi, Hasan Oguz; Kiraz, Hasan Ali; Demir, Emin Tunc; Adali, Yasemen; Elmas, SaitPurpose: This experimental sepsis model created with Escherichia coil aimed to investigate the histopathological effects of two different doses of ozone combined with antibiotherapy on lung tissue. Methods: Rats were divided into 5 groups. Then sepsis was induced intraperitoneally in the first 4 groups. The 1st group was treated with cefepime, the 2nd and 3rd groups were treated with cefepime combined with ozone at a dose of 0.6 mg/kg and 1.1 mg/kg. Lung tissue sections were stained with hematoxylin-eosin and assessed under light microscope and scored between 0-4 in terms of histopathological findings. Results: In the comparisons between Group 1 and Group 4 in terms of cellular damage (p=0.030), inflammation (p=0.000) and overall score (p=0.007), statistically significant positive effects were observed in favor of Group 1. In the comparisons of Groups 2 and 3 with Group 4, only positive effects were observed in terms of inflammation (p=0.020, p=0.012, respectively). Conclusion: Although negative histopathological effects of ozone on tissue injury were detected, it was noteworthy that the increase in the ozone dose reduced the number of damaged parameters.Öğe Simplified Weaning After Use of Quetiapine in a Patient: Case Report(Galenos Yayincilik, 2020) Inal, Mehmet Turan; Memis, Dilek; Demir, Emin Tunc; Uyar, Ahmet Senol; Arslan, Ismail; Bozkurtlu, PoyrazDelirium is an organic dysfunction including the brain's inflammatory response to injury, hormonal effects and changes in neurotransmission and neural network. Delirium is one of the major causes of weaning difficulty in intensive care unit (ICU) patients. In this case report, we tried to explain the successful weaning procedure in a patient using quetiapine after trying all treatment options due to delirium in the ICU. This report emphasizes that second-generation antipsychotics should be kept in mind in patients who cannot be disconnected from the mechanical ventilator due to delirium.Öğe Use of Sengstaken-Blakemore tube in a different indication: A case report(Turkish Assoc Trauma Emergency Surgery, 2022) Demir, Emin Tunc; Cuhadar, MehmetTracheostomy has become a common procedure in today???s intensive care units. On the other hand, tracheostomy has some life-threatening complications. In here, we presented that an interesting case of a tracheaesophageal fistula, rare complication of surgical tracheostomy, caused by posterior tracheal membrane laceration than has progressed to form a single passage. This passage progressively led both air trapping in gastrointestinal tract due to required mechanical ventilatory support and reflux of gastrointestinal content into tracheobronchial tree. Conventional measures were not beneficial, nor immediate surgical repair was feasible due to unstable condition of the patient. Then, a Sengstaken???Blackmore tube was introduced and overwhelmed the condition.