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Öğe The comparison of electron microscopy and scintigraphy in determining the protective effect of dimethylsulphoxide (DMSO) on ischemia/reperfusion injury through pringle maneuver(H G E Update Medical Publishing S A, 2001) Hatipoglu, AR; Temiz, E; Yüksel, M; Hoscoskun, Z; Coskun, I; Hüseyinova, GBackground/Aims: We investigated the role of the electron microscopy and hepatobiliary scintigraphy in determining the effect of DMSO (dimethysulphoxide) and ischemia/reperfusion injury in the liver after the Pringle maneuver. Methodology: Twenty-four rabbits were divided into the following groups; A: Control group, B: Pringle, C: 10mg/kg DMSO, D: 1g/kg DMSO + Pringle. Group A was considered as a control group and only laparotomy was applied. Group B was exposed to Pringle maneuver only. Group C:was given 10mg/kg of DMSO via the vena cava inferior. Group D was given 1g/kg of DMSO- A clamp was fastened for the groups of B, C and D in the 30th minute of the Pringle maneuver and a biopsy was applied five minutes later. Fifteen minutes later a dynamic hepatobiliary scintigraphy was applied. From dynamic images, liver peak time and activity half time of the liver were obtained. Results: It was found that liver peak time and liver activity half time values of the group B, C and D were significantly longer than group A. Liver peak time and liver activity half time values of group B was not different from group C. However, some values of group D were found to be significantly shorter than groups B and C. In the electron microscopy examination, only in group B were some specific degenerative changes observed in the sinusoids. We observed less irreversible changes in group C than in group B. Oh the other hand, the least irreversible changes were in group D. Conclusions: As a conclusion, while electron microscopy is regarded as the gold standard, hepatobiliary scintigraphy may be thought of as an easily applicable: method in determining the ischemic reperfusion injury in the clinical comparison of the protective agents.Öğe Laparoscopic versus open cholecystectomy: Effect on pulmonary function tests(H G E Update Medical Publ Ltd., 2000) Coskun, I; Hatipoglu, AR; Topaloglu, A; Yoruk, Y; Yalcinkaya, S; Caglar, TBackground/Aims: Operations often cause impairment in respiration due to pain. This study was designed to compare the changes in pulmonary function tests after open and laparoscopic cholecystectomy. Methodology: Two groups of 35 patients were randomly set up. Each patient had 3 pulmonary function tests performed and 2 postero-anterior grid chest roentgenograms taken. All of these data were evaluated by the same group of investigators. Results: After taking into consideration the difference between pulmonary function tests, values were not significant (P less than or equal to 0.05). All pulmonary function test values decreased significantly on the 1st postoperative day (P less than or equal to 0.05). When postero-anterior chest roentgenograms were compared no clinically evident atelectasis except 3 lineary was seen in the laparoscopic cholecystectomy group, whereas 5 lineary, 7 focal, and 3 segmentary atelectasia were encountered in the open cholecystectomy group (P less than or equal to 0.05). Conclusions: We believe that laparoscopic cholecystectomy has more advantages when speaking of postoperative pulmonary function tests and atelectasia.Öğe Laparoscopic versus open cholecystectomy: effect on pulmonary function tests [Proceedings Papert](Medimond S R L, 1998) Coskun, I; Topaloglu, A; Yoruk, Y; Yalcinkaya, S; Caglar, TTo compare the changes in pulmonary function tests (PFT) after open and laparoscopic cholecystectomy, two groups of 25 patients were set up. Each patient had 3 PFTs performed and 2 PA grid chest roentgenograms taken. After taken into consideration the difference between PFT values were not significant (p less than or equal to 0.05). All PFT values decreased significantly on the first postoperative day (p less than or equal to 0.05). When PA chess roentgenograms were compared no clinically evident atelectasis except 1 lineary was seen in laparoscopic cholecystectomy group whereas 3 lineary, 4 focal, and 1 segmentary atelectasia were encountered in open cholecystectomy group (p less than or equal to 0.05). We believe that laparoscopic cholecystectomy has more advantages when speaking of postoperative PFT and atelectasia.Öğe Lymphangiomatosis of the colon mimicking acute appendicitis(Wolters Kluwer Medknow Publications, 2011) Yagci, Mehmet Ali; Sezer, Atakan; Yeldan, Eyup; Coskun, I; Hatipoglu, Ahmet Rahmi; Altaner, Semsi; Umit, Hasan[Abstract Not Available]Öğe Retroperitoneal localization of hydatid cyst disease(H G E Update Medical Publ Ltd., 2001) Hatipoglu, AR; Coskun, I; Karakaya, K; Ibis, CIn this study we discuss a rare case; hydatid cyst disease that is located in the retroperitoneum. Two cases were treated in our department with hydatid cyst disease located in the retroperitoneum; one of the cysts was in the minor pelvis and the other was on the left psoas muscle. Diagnosis was confirmed with blood tests, and radiological examinations. The cyst wall was excised partially and was oversewn. Following the operation both of the patients were given albendasole tablets for 10 weeks with blood count and liver enzyme monitorization. Hydatic cysts located in retroperitoneum were treated successfully. Especially in the endemic areas hydatid cyst should be remembered when evaluating cystic masses in the retroperitoneum. It can be treated successfully with surgery.Öğe The rupture of hepatic hydatid disease into the right hepatic vein and bile ducts: A case report(H G E Update Medical Publ Ltd., 1996) Coskun, I; Esenturk, M; Yoruk, YEchinococcus granulosus and Echinococcus multilocularis cause liver hydatid disease. One of its most common complications is rupture into the bile ducts; however, penetration of a cyst into a vessel is a very rare complication. We detected a defect (2x1 cm) on the wall of the right hepatic vein, in addition to three distinctive ruptures into the bile ducts, in our case. For systemic hypotension due to a bleeding during operation and to repair the vessel wall defect, and urgent right thoracotomy followed by a radical phrenotomy was needed. We were able to reach the operation site easily and repaired the vessel wall with polypropylene suture. Because of the occurrence of these two complications together and the difficulties of the operation, we decided to report this case.Öğe Simultaneous operation for coexisting lung and liver hydatid cysts: A treatment modality(H G E Update Medical Publ Ltd., 1998) Yoruk, Y; Yalcinkaya, S; Coskun, I; Ekim, T; Kose, S; Mehmet, RBACKGROUND/AIMS: Hydatid disease is very common in our region, Whether or not coexisting cysts of lung and liver should be operated on simultaneously is a challenging question. METHODOLOGY: Of 127 patients operated on for hydatid cysts of the lung between 1990 and 1995, 23 (18%) had coexisting hydatid cysts of the right lung and liver. There were 12 male and 11 female patients with an average age of 34 years. RESULTS: All patients had simultaneous operations for both organs via right thoracotomy with an incision in the diaphragm (phrenotomy). In the lung, cystotomy and capitonnage were performed in 21 patients and wedge resection in 2; in the liver, cystotomy and capitonnage were performed in all 23 patients. No hospital mortality occurred. CONCLUSION: Coexisting hydatid cysts of the right lung and liver should be surgically treated simultaneously.Öğe An unusual CT(Bmj Publishing Group, 2005) Baydar, S; Hatipoglu, A; Sezer, A; Ibis, C; Coskun, I; Umit, H; Tezel, A[Abstract Not Available]
