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Öğe Effects of the incson preference n acetabular surgery on the postoperatve functonal outcomes(Wolters Kluwer Medknow Publications, 2019) Erem, M.; Copuroglu, C.; Copuroglu, E.; Ciftdemir, M.; Ozcan, M.; Saridogan, K.Background: Many factors are known to affect the functional outcomes of the acetabular surgery. The aim of this study is to evaluate the effects of incision preferences and number of incision on scores and clinical functional outcomes. Patients and Methods: Forty-seven adult patients who had undergone acetabular surgery and had been followed up for at least 1 year in our clinic were included in the study. Demographic data, trauma type, acetabular fracture type based on the Judet ve Letournel classification, presence of any additional traumatic fractures, time to surgery, operation duration, surgical technique, and postoperative complications were recorded. Range of motion measurements, SF-36 and Harris Hip function scale score, and full weight-bearing times were evaluated on the postoperative first year follow-up and reviewed retrospectively. Results: Our study suggests that use of double incisions in the surgery of associated fractures shortens the full weight-bearing time. The localization and the number of incisions were found to be unrelated with the Harris Functional Hip scale, SF-36 (PCS, physical component score), and SF-36 (mental component score, MCS) scores. Conclusion: Incision type and number of incisions must be determined based on the fracture type and fracture localization for better functional outcomes. The factors that have the most effects on the functional outcomes are the type and the localization. In associated fractures, performing multiple incisions reduces the time for full weight bearing and enables patients to return to their daily routine early but have no effect on the functional outcomes.Öğe GENETIC ANALYSES OF THE NF1 GENE IN TURKISH NEUROFIBROMATOSIS TYPE I PATIENTS AND DEFINITION OF THREE NOVEL VARIANTS(Macedonian Acad Sciences Arts, 2017) Ulusal, S. D.; Gurkan, H.; Atli, E.; Ozal, S. A.; Ciftdemir, M.; Tozkir, H.; Karal, Y.Neurofibromatosis Type I (NF1) is a multi systemic autosomal dominant neurocutaneous disorder predisposing patients to have benign and/or malignant lesions predominantly of the skin, nervous system and bone. Loss of function mutations or deletions of the NF1 gene is responsible for NF1 disease. Involvement of various pathogenic variants, the size of the gene and presence of pseudogenes makes it difficult to analyze. We aimed to report the results of 2 years of multiplex ligation-dependent probe amplification (MLPA) and next generation sequencing (NGS) for genetic diagnosis of NF1 applied at our genetic diagnosis center. The MLPA, semiconductor sequencing and Sanger sequencing were performed in genomic DNA samples from 24 unrelated patients and their affected family members referred to our center suspected of having NF1. In total, three novel and 12 known pathogenic variants and a whole gene deletion were determined. We suggest that next generation sequencing is a practical tool for genetic analysis of NF1. Deletion/duplication analysis with MLPA may also be helpful for patients clinically diagnosed to carry NF1 but do not have a detectable mutation in NGS.Öğe Periosteal osteosarcoma with diffuse bilateral pulmonary metastasis: A case report(Springer, 2021) Kokceli, A.; Ozpuyan, F.; Ciftdemir, M.; Ustabasioglu, F. E.[Abstract Not Available]Öğe Posterior dislocation of the sternoclavicular joint(Lithographia, 2011) Ciftdemir, M.; Copuroglu, C.; Ozcan, M.[Abstract Not Available]Öğe Prognosis and risk factors of nerve injuries in displaced pediatric supracondylar humerus fractures(Wolters Kluwer Medknow Publications, 2020) Ozcan, M.; Altinoz, O.; Erem, M.; Ciftdemir, M.; Copuroglu, C.; Turan, F. N.Background: Supracondylar humerus (SCH) fractures are serious injuries due to the neighborhood of critical neural and vascular structures. One of the most devastating complications of SCH fractures is neurological damage, since it may cause permanent disability. The aim of this study is to categorize neurological complications, to report long-term functional outcomes, and to determine risk factors associated with childhood SCH fractures. Methods: The records of 375 children were reviewed retrospectively. Data about amount and direction of displacement, the shape of the fracture, age at the time of fracture, gender, time from impaction to surgery, time of surgery, type of neurological injury, and recovery time were recorded. Results: Neurological complications were seen in 37 (9.85%) children. Thirteen (35.1%) of the children had an iatrogenic nerve injury. All iatrogenic injuries were fully recovered in this study. However, 2 children who had combined neurological injury of radial, ulnar, and median nerves did not recover. Nearly 95% of all children who had neurological injury recovered fully. An anterior long and sharp bone fragment (spike) was observed in most of the children with neurological injury, and this spike was seen in 14 (58.3%) patients who had a trauma-related injury (n = 24). Conclusion: The prognosis of these nerve injuries is excellent, especially the iatrogenic ones. A long and sharp bone fragment (spike) may be responsible for nerve injuries in some children. Surgical exploration is not necessary after an iatrogenic nerve injury when there is no neurotmesis. Patience and care are utmost needed to handle neurological complications.Öğe The relation between the interpedicular distance and the maximum pedicular screw length in lumbar one vertebra(Edizioni Minerva Medica, 2011) Copuroglu, C.; Ciftdemir, M.; Yilmaz, A.; Ozcan, M.; Kaya, M.; Yalniz, E.Aim. The aim of this paper was to demonstrate the relation between the distance of the midline of the corpus and the screw entry point on the pedicle and the maximum screw length that can be applied in the pediculocorporeal screw trajectory. Methods. The distance between two pedicular screw entry points and the distance between screw entry point and the anterior cortex of the vertebra corpus in the midline, on computed tomography (CT) sections and the same distances on cadaveric bony L1 specimens, were measured. Interpedicular distance was divided into two and the distance between the midline and the screw entry point was found. These measurements were compared and a constant ratio was observed. The pedicular screw entry point was accepted as the point just lateral to the inferior articular process at the mid level of the transverse process. Results. When these measurements were compared, a constant ratio was observed. The ratio between the distance of the midline of the vertebra and the screw entry point and the distance between the screw entry point and the midline anterior cortex of the vertebral body, was 2.5 cm. When the distance between the midline of the vertebra and the screw entry point during the operation or by measuring half of the interpedicular distance on plane roentgenograms, is measured, the maximum length of the pedicular screw can be estimated. Conclusion. In this study, we described an easy method of determining the maximum pedicular screw length by measuring the distance between the midline level of the vertebra corpus (spinous process level) and pedicle screw entry point on coronal section.Öğe Sexual dysfunction of male, after pelvic fracture(Springer Heidelberg, 2017) Copuroglu, C.; Yilmaz, B.; Yilmaz, S.; Ozcan, M.; Ciftdemir, M.; Copuroglu, E.Purpose Pelvic fractures are usually the result of high-energy trauma, and sexual dysfunction after a pelvic fracture is an often complication. Though organic pathologies can be the reason for sexual disorders, psychological factors following a trauma may also be linked to sexual problems. We aimed to evaluate the frequency of sexual dysfunction after pelvic fractures, and help these patients with their usually undisclosed sexual problems, and offer them support. Materials and methods During a 4-year period, between June 2008 and May 2012, 40 male patients (out of 57) with a mean age of 42.6 years (range 18-65 years) were evaluated retrospectively. Patients having organic pathologies (vascular, neural, and urogenital system pathologies) were excluded from the study. Patients were requested to complete the Arizona Sexual Experience Scale (ASEX), which is a 5-item self-evaluation scale. According to the results of the questionnaire, patients needing supportive treatment were referred to the psychiatry department. Results Twenty-two patients (55 %) scored 10 points or less in the ASEX questionnaire (normal). Eighteen patients (45 %) had 11 points or more (can be problematic). Four of these 18 patients had a score of 19 points or more (needing psychiatric evaluation). Patients with a score of >= 19 points, for any one item with a score of 5 or 6 points, or any three or more items with a score of 4 points were considered to have a high probability of sexual dysfunction after psychiatric evaluation. Conclusion The frequency of sexual dysfunction in pelvic fractured patients was tested, and the need for investigating sexual disorders is stressed. This study attracts attention to sexual dysfunction after pelvic fractures and the necessity of referring these patients to the related clinics, for treatment. Level of evidence Retrospective case series.Öğe When the sourcil width is larger than the femoral neck, it can be a predictor for an upcoming hip fracture(Edizioni Minerva Medica, 2011) Copuroglu, C.; Yilmaz, A.; Ozcan, M.; Ciftdemir, M.; Unver, K. V.; Kaya, M.; Copuroglu, E.Aim. Response of the bone to pressure depends on the strength of the pressure applied. If the load, transferred from the sourcil to the femoral head, is heavy and if the femoral neck is large, development of load carrying structures will be greater. We aimed to evaluate the relationship between the width of the sourcil and the width of the femoral neck and their relation with the fracture type of the hip in correlation with the neck-shaft angle. Methods. This is a retrospective case series study (N.=320) including the instutional data between January 2007 through April 2010. The medial and lateral side of the sourcil was pointed on the AP X-ray, and the distance between these two points was measured. On the same AP X-rays, the radius at the thinnest width of the femoral neck was measured in millimetres. The width of the sourcil and the width of the femoral neck in normal hips were compared with the measurements of the fractured hips. Neck-shaft angles of all the hips were also measured. Results. The width of the sourcil is mostly equal to the width of the femoral neck in normal hips. The width of the sourcil was greater than the width of the femoral neck in hip-fractured patients. This shows that, if the sourcil is bigger than the femoral neck, the femoral neck cannot carry as much load as the sourcil and fractures may happen. If the neck-shaft angle is smaller than normal hips, we observed that collum femoris is broken and if the neck-shaft angle is bigger than normal hips, then intertrochanteric femur fracture occurs. Conclusion. When the sourcil width is larger than the femoral neck width, it can be a predictor for an upcoming hip fracture. Varus in the neck-shaft angle is a predictor for femoral neck fracture and valgus is a predictor for intertrochanteric fracture.
