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Öğe Adult supratentorial extraventricular anaplastic ependymoma: a rare case(Springer, 2020) Binboga, B.; Puyan, F. Oz; Kurt, N.; Can, N.[Abstract Not Available]Öğe Ciliated hepatic foregut cyst(Springer, 2017) Tutug, B. Binboga; Usta, U.; Can, N.; Genc, E.[Abstract Not Available]Öğe CLINICALLY UNDETECTABLE OCCULT THYROID PAPILLARY CARCINOMA PRESENTING WITH CERVICAL LYMPH NODE METASTASIS(Editura Acad Romane, 2016) Tastekin, E.; Can, N.; Ayturk, S.; Celik, M.; Ustun, F.; Guldiken, S.; Sezer, A.Background. Occult papillary thyroid carcinoma presented as isolated cervical lymphadenopathy without clinical and radiologic findings has been rarely reported. Case report. A 47 years old female patient admitted to otorhinolaryngology clinic with 4X3 cm sized cervical mass. Physical examination of the patient was noted as a nontender, firm, mobile lymph node at right lateral cervical region. There was no inflammatory or infection disease in the history of patients anamnesis and no abnormal value on laboratory tests. Ultrasound screening of the neck detected a lymph node with suspicious features for malignancy. Head and neck examination was normal and there is no evidence of a tumoral mass or nodule in the thyroid gland. Whole body scan of MRI showed no pathologic sign both in the neck and body. Excisional biopsy was performed and revealed a carcinoma with papillary morphology. Immunohistochemical staining features of the tumor confirmed a papillary carcinoma derived from the thyroid gland. Second look USG of the neck and thyroid was performed but it revealed no tumoral mass. The patient underwent total thyroidectomy with right functional and central lymph node dissection. Histological examination of the thyroid gland showed multicentric 2 mm sized, three foci of papillary carcinoma located in bilateral thyroid lobes and metastatic lymph nodes in the right side of the neck. Conclusion. A metastatic cervical lymph node can be evidence of a clinically undetected occult papillary thyroid carcinoma. Specific immunohistochemistry staining of specimen may lead to appropriate surgery and progression of carcinoma may be hindered by application of additional RAI therapy.Öğe Dyshormonogenetic goiter with malignant transformation: a rare case(Springer, 2021) Demirtas, E. Mercan; Can, N.; Usta, I.; Oztorun, B.[Abstract Not Available]Öğe Extramedullary plasmacytoma in tongue: A rare entity(Springer, 2013) Tastekin, E.; Can, N.; Azatcam, M.; Puyan, F. Oz; Arslan, A.[Abstract Not Available]Öğe Genetic alterations detected in metastatic cutaneous malignant melanoma cases, single centre experience(Springer, 2021) Usta, I.; Can, N.; Demirtas, E. Mercan; Bagis, M.; Topuz, C.; Avci, B.; Oztorun, B.[Abstract Not Available]Öğe Incidental adrenal neuroma: A case report(Springer, 2013) Can, N.; Tastekin, E.; Isler, S.; Azatcam, M.; Peglivanoglu, Z.[Abstract Not Available]Öğe Intranasal encephalocele: Presentation of two cases(Springer, 2013) Can, N.; Tastekin, E.; Isler, E.; Aslan, A.; Azatcam, M.[Abstract Not Available]Öğe Next Generation Sequencing (NGS) in acute myeloid leukaemia: a centre experience(Springer, 2021) Oz Puyan, F.; Karaman Gulsaran, S.; Umit, E. G.; Usta, I.; Tastekin, E.; Can, N.; Kirkizlar, O.[Abstract Not Available]Öğe A novel nonsense mutation of the CYLD gene in a Turkish family with multiple familial trichoepithelioma(Wiley, 2020) Sarikaya Solak, S.; Yalcintepe, S.; Atahan, C.; Nagy, N.; Can, N.[Abstract Not Available]Öğe Oxcarbazepine-induced Stevens-Johnson syndrome: a pediatric case report [Meeting Abstract](Wiley-Blackwell, 2016) Beken, B.; Can, C.; Atci, A.; Can, N.; Yazicioglu, M.[Abstract Not Available]Öğe Poorly differentiated thyroid carcinoma accompanying with follicular variant papillary thyroid carcinoma: a case report(Springer, 2021) Betul, D.; Can, N.; Puyan, F. Oz; Yalta, T. D.; Usta, I.; Bulbul, B. Y.; Sezer, A.[Abstract Not Available]Öğe A RARE CLINICAL PRESENTATION: A PATIENT WITH CHRONIC RENAL FAILURE, SECONDARY HYPERPARATHYROIDISM AND CALCIPHYLAXIS(Editura Acad Romane, 2016) Celik, M.; Ayturk, S.; Celik, H.; Can, N.; Kucukarda, A.; Sezer, A.; Guldiken, S.Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is usually observed in women and it is a serious complication of hyperparathyroidism secondary to chronic renal failure. CUA is characterized by ischemic tissue loss secondary to progressive vascular degeneration. Although it is rare, it may end up with sepsis and organ failure and can be fatal. Its pathogenesis is not fully understood, but it is thought that it occurs secondary to increased calcification activators such as oxidized LDL, TNF-alpha, calcitriol, fibronectin, collagen-I, and TGF-1 alpha. The most effective treatment is managing underlying pathology and decreasing serum calcium and phosphorus levels. In this report, we aimed to present an end stage renal failure case with coexisting hyperparathyroidism, hyperthyroidism and calciphylaxis in whom cutaneous manifestations were healed 6 months after parathyroidectomy.Öğe A rare entity of primary cutaneous, extranodal NK/T-cell lymphoma, nasal type with loss of CD56 expression; Case report(Springer, 2017) Puyan, F. Oz; Umit, E. G.; Can, N.; Cezik, M.; Demir, A. M.; Kutlu, A. K.[Abstract Not Available]Öğe A rare lesion of stomach gastritis cystica polyposa/profunda, report of two cases(Springer, 2017) Cezik, M.; Can, N.; Genc, E.; Sarikas, N.[Abstract Not Available]Öğe A rare metastasis of renal cell carcinoma: gingiva(Springer, 2021) Usta, I.; Can, N.; Bagis, M.; Canakci, F. G.[Abstract Not Available]Öğe The relationship between Ga-68 PSMA accumulation intensity and Gleason score, PSA levels in primary staging and evaluation of biochemical recurrence of prostate cancer: The preliminary results(Springer, 2017) Aktas, G. Ege; Caloglu, V.; Can, N.; Akdere, H.; Ustun, F.; Altun, G. Durmus[Abstract Not Available]Öğe Signet ring adenocarcinoma of prostate: Two cases report(Springer, 2013) Tastekin, E.; Inci, O.; Can, N.; Azatcam, M.; Ciftci, T.; Ozdedeli, K.[Abstract Not Available]Öğe SURVIVIN POSITIVITY AND PROGNOSTIC FACTORS IN PAPILLARY THYROID CARCINOMAS(Editura Acad Romane, 2021) Keskin, E. Usturali; Tastekin, E.; Can, N.; Mut, A. N.; Celik, M.; Bulbul, B. Yilmaz; Puyan, F. OzContext. Papillary thyroid carcinoma(PTC)s are the indolent progressive tumours. Survivin is a unique bifunctional protein with cell cycle regulation and apoptosis inhibition. The expression of this protein has been shown to be increased in thyroid tumours correlated with aggressive behavior from well differentiated to anaplastic. Objective. In this study, we aimed to investigate the relationship between immunohistochemically survivin expression and tumour-associated prognostic factors in papillary thyroid carcinomas. Design. In patients with thyroidectomy, we compared the clinicopathological findings and immunohistochemical positivity for survivin. Subjects and Methods. In 109 patients, sex, age, tumour size, histological tumour variant, tumour focality, tumour border pattern, tumour peripheral/intratumoural lymphocytic and stromal response, intraglandular spread, extrathyroideal spread, lymph node metastases, lymphocytic tiroiditis and relationships of these findings with survivin positivity were investigated. Results. When we indicated the tumour size and compared it with survivin expression, tumour size correlates with, survivin expression (p = 0.016). Survivin expression was correlated statistically significant with lymphovascular invasion, without stromal response and with intraglandular extension respectively (p<0.001, p = 0.043, p<0.001). No significant correlation was found between other clinicopathological parameters and survival. Conclusion. Few studies have investigated the relationship of survivin expression with prognosis in thyroid papillary carcinomas and showed that survivin was a poor prognostic marker. If its expression is detected in preoperative cytology smears, it may affects the surgical treatment strategy. When it is detected in the tissue, postoperative radioactive iodine treatment plan may be modified and the need for more aggressive follow-up may be considered.Öğe Testicular lymphoma: A case report(Springer, 2013) Tastekin, E.; Inci, D.; Can, N.; Arslan, A.[Abstract Not Available]