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Öğe Anomalous origin of the right coronary artery from the left anterior descending artery in a patient with single left coronary artery: A rare coronary artery anomaly and review of the literature(Elsevier Ireland Ltd, 2008) Erdogan, Okan; Buyuklu, Mutlu; Aktoz, MeryemA 44-year-old woman with hypertension was admitted because of recent onset chest pain. Coronary angiography revealed an anomalous right coronary artery originating as a separate branch from the left anterior descending artery. Associated with the present case all published case reports were thoroughly investigated and presented as a review of the literature. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Cardiac rhabdomyoma in an adult patient presenting with right ventricular outflow tract obstruction(Elsevier Ireland Ltd, 2008) Aktoz, Meryem; Tatli, Ersan; Ege, Turan; Yalcin, Omer; Buyuklu, Mutlu; Aksu, Feza; Gul, CetinWe present a 24 year old woman with cardiac rhabdomyoma. Cardiac rhabdomyoma is the most common benign cardiac tumor in infants, but in adults, cardiac rhabdomyoma is very rare. These tumors are often spontaneously reversible because they are associated to the right or left ventricular outflow tract obstruction, tachyarrhythmias and heart failure where surgery is necessary. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Coronary artery ectasia in a patient with Behcet's disease(Saudi Med J, 2007) Tatli, Ersan; Surucu, Huseyin; Aktoz, Meryem; Buyuklu, MutluBehcet's disease is a multisysternic disease of unknown etiology. Disease manifestations consist of recurrent oral and genital ulceration, skin lesions, and relapsing ocular inflammation. Arterial involvement is an uncommon complication of Behcet's disease, and it most frequently affects the abdominal aorta followed by femoral artery, and the pulmonary artery. Coronary lesions in Behcet's disease have been little reported in the literature. A-36-year-old female with 6-year history of Behcet's disease was hospitalized with ectasia of the left main coronary artery. This unusual vascular complication Behcet's disease is presented.Öğe Does carvedilol therapy reduce QT dispersion in patients with heart failure?(Termedia Publishing House Ltd, 2008) Tatli, Ersan; Aktoz, Meryern; Gul, Cetin; Buyuklu, Mutlu; Kurum, TurhanIntroduction: Carvedilol therapy increases left ventricular ejection fraction, and reduces mortality and morbidity rates. However, there are very limited data relating to the effect of carvedilol on QT dispersion (QTd). In this study, we investigated the effect of carvedilol therapy on QTd in patients with heart failure. Material and methods: Fifty-six patients with heart failure and a left ventricular ejection fraction less than 40% were prospectively included in the study. Clinical examination, determinations of plasma levels of tumour necrosis factor-alpha (TNF-alpha), interleukin 2 (IL-2) and IL-6, electrocardiography and radionuclide study were performed at baseline and repeated at the end of the 4(th) month of carvedilol therapy. From standard 12-lead electrocardiograms the maximum and minimum QT intervals, corrected QT intervals and corrected QTd values were calculated at baseline, and after the 4(th) month of carvedilol therapy. Results: At the end of the 4(th) month, IL-6 (from 9.8 +/- 6.4 to 5.4 +/- 0.7 pg/ml) and TNF-a (from 10.9 +/- 4.6 to 6.0 +/- 4.9 pg/ml) levels, QTd, corrected QTd, resting heart rate, and Systolic blood pressure were significantly decreased, and left ventricular ejection fraction and NYHA functional class were improved by carvedilol therapy (QTd from 66 +/- 22 to 28 +/- 13 ms, P<0.001, corrected QTd from 72 +/- 23 to 30 +/- 14 ms, P<0.001). However, maximum corrected QT and maximum QT values did not change significantly, while minimum QT and minimum corrected QT values significantly increased. Conclusions: Carvedilol therapy for 4 months resulted in a significant reduction in QTd.Öğe Effects of carvedilol on right ventricular ejection fraction and cytokines levels in patients with systolic heart failure(Elsevier Ireland Ltd, 2008) Tatli, Ersan; Kurum, Turhan; Aktoz, Meryem; Buyuklu, MutluBackground: Right ventricular (RV) dysfunction frequently complicates advanced left ventricular (LV) heart failure and contributes to an unfavorable prognosis. It is known that carvedilol increases left ventricular ejection fraction (LVEF) significantly, and carvedilol reduces mortality by associating with improvement in LV function. However, the effect of carvedilol on RV function in heart failure has not adequately been studied, so far. The objective is to establish whether the addition of carvedilol has an additive beneficial effect on RVEF and cytokines levels in patients with heart failure who are already receiving treatment with angiotensin-converting enzyme (ACE) inhibitors, digoxin and diuretics. Methods: In this single-centre, prospective, randomized study, 74 patients with heart failure with an LVEF less than 40% and already receiving digoxin, ACE inhibitors and diuretics for 6 months as the standard therapy were randomly assigned to receive either carvedilol (n= 44) or placebo (n= 30). Patients received an initial dosage of 6.25 mg carvedilol or placebo twice daily for 2 weeks, which was then increased at 2-week intervals (if tolerated), first to 12.5 mg and, finally, to a target dosage of 25 mg twice daily. Clinical examinations, radionuclide studies, and determinations of plasma levels of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-2 and IL-6 were performed at baseline and repeated 4 months after random assignment. Primary end points were New York Heart Association functional class, RVEF and plasma cytokines levels. Results: Patients treated with carvedilol had a significant improvement in functional class compared with the baseline values (P = 0.001), with a decrease in the levels of cytokines (IL-6 [P=0.02] and TNF-alpha [P= 0.02]). LVEF increased from 21.4 +/- 8.8% to 27.8 +/- 10.8% and RVEF increased from 28.8 +/- 4.2% to 36.3 +/- 2.6% in the carvedilol group (P= 0.003). Conclusions: Carvedilol treatment for 4 months resulted in a significant improvement of RVEF, which paralleled the improvement of LVEF and the decreasing of TNF-alpha and IL-6 levels in patients with systolic HF. Published by Elsevier Ireland Ltd.Öğe Electrocardiographic abnormality: hyperkalaemia mimicking isolated acute inferior myocardial infarction(Lippincott Williams & Wilkins, 2008) Tatli, Ersan; Buyuklu, Mutlu; Onal, Baris[Abstract Not Available]Öğe Is abnormality of double right coronary artery seen more frequently in Turkey than the others?(Elsevier Ireland Ltd, 2008) Tatli, Ersan; Buyuklu, Mutlu; Altun, Armagan; Yilmaztepe, Mustafa[Abstract Not Available]Öğe Is coronary revascularization necessary for patients with well-developed coronary collaterals and coronary artery disease?(Elsevier Ireland Ltd, 2008) Tatli, Ersan; Buyuklu, Mutlu[Abstract Not Available]Öğe May positive U waves in V1-V3 leads predict left main coronary artery occlusion?(Aves Yayincilik, 2008) Tatli, Ersan; Yildirim, Tarik; Aktoz, Meryem; Buyuklu, Mutlu[Abstract Not Available]Öğe A patient with double right coronary artery and acute inferior myocardial infarction due to the critical lesion in one of them(Elsevier Ireland Ltd, 2007) Tatli, Ersan; Buyuklu, Mutlu; Altun, Armagan; Yilmaztepe, Mustafa[Abstract Not Available]Öğe A rare association recognized before cardiac surgery: Persistent left superior vena cava and secundum atrial septal defect(Elsevier Ireland Ltd, 2009) Buyuklu, Mutlu; Ufacik, Osman; Pirhan, Osman; Tatli, ErsanOne of the most common congenital anomalies of systemic veins is persistent left superior vena cava. Association of persistent left superior vena cava with other congenital cardiac diseases is common and frequently encountered during diagnostic studies. Contrast echocardiography has an important role in the diagnosis. Owing to the fact that cardiopulmonary by-pass procedure may be problematic in patients with persistent left superior vena cava, this anomaly should be detected before cardiac surgery and required measures should be taken. Our case is an association of persistent left superior vena cava detected in a patient to be operated for secundum atrial septal defect. We report the case owing to its low frequency and to emphasize the importance of detection before cardiac surgery. (c) 2007 Published by Elsevier Ireland Ltd.Öğe Right coronary artery aneurysm: Possible relation with obesity?(Elsevier Ireland Ltd, 2008) Tatli, Ersan; Buyuklu, Mutlu; Onal, Baris; Yel, Mesih; Kurum, TurhanAneurysms of the coronary arteries are uncommon occurrences that usually develop secondary to atherosclerosis and are often asymptomatic. We present a 57-year-old male patient who presented with the diagnosis of an inferior wall acute myocardial infarction with a large aneurysm of the right coronary artery and with morbid obesity. To the best of our knowledge, a relationship between body mass index and coronary artery aneurysm has not been reported in the literature so far. We speculated that there is a relationship between coronary artery aneurysm and body mass index. (C) 2007 Published by Elsevier Ireland Ltd.Öğe An unusual complication of pneumococcal pneumonia: Acute tamponade due to purulent pericarditis(Elsevier Ireland Ltd, 2007) Tatli, Ersan; Buyuklu, Mutlu; Altun, ArmaganThe incidence of purulent pericarditis has declined, however mortality remains high. Few cases so far of cardiac tamponade related with purulent pericarditis which is a rare complication of pneumococcal pneumonia have been published in the literature. We report a case of the development of cardiac tamponade due to pneumococcal pneumonia and emphasize the importance of early recognition, prompt institution of appropriate antibiotic therapy, and early surgical drainage for survival. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Öğe Ventricular septal rupture presenting with hyperosmolar hyperglycemic nonketotic coma(Saudi Med J, 2007) Tatli, Ersan; Surucu, Huseyin; Buyuklu, Mutlu; Yilmaztepe, Mustafa[Abstract Not Available]
