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    Investigation of indoor molds and allergic diseases in public primary schools in Edirne city of Turkey
    (Allergy Immunol Soc Thailand,, 2011) Celtik, Coskun; Okten, Suzan; Okutan, Ozlem; Aydogdu, Halide; Bostancioglu, Musa; Ekuklu, Galip; Asan, Ahmet
    Background: Studies evaluating the role of indoor molds in the development of allergic or respiratory symptoms in schools are few in childhood. Objective: This study aimed to investigate relation between indoor molds and allergic diseases or respiratory symptoms in primary school's children in Edirne, Turkey. Methods: Ten public primary schools were included into the study. A thorough assessment, using a questionnaire and inspection surveys was carried out. The concentration of culturable mold was assessed in the dust samples in the schools. Indoor temperature and humidity were measured. A total of 1374 students who completed valid questionnaires were included in the study, and dust-samples were collected from the schools. Results: Cumulative and current prevalence rates of wheezing, asthma, allergic rhinitis, and atopic dermatitis were found as 31.4%, 9.3%, 16.2%, 6.0% and 13.4%, 11.9%, 15.1%, 2.1%, respectively. The most frequent mold-species detected in indoor dusts were Cladosporium, Penicillium, Alternaria and Aspergillus. Although the prevalence rates of allergic diseases and respiratory symptoms were high, indoor mold amounts were low in the schools in our region and no significant correlation was determined between indoor mold amount and the prevalence of these diseases in schools or classrooms. Conclusion: Even though allergic molds are present in schools, the mold-exposure may not be an important predisposing factor for development of allergic and respiratory diseases the schools in our region. (Asian Pac J Allergy Immunol 2011;29:42-9)
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    The Reasons of Elevated Serum Transaminases in Childhood
    (Turkish Biochem Soc, 2008) Celtik, Coskun; Erbas, Hakan; Kursun, Oemer Serhat; Bostancioglu, Musa; Inan, Mustafa; Oner, Naci; Acunas, Betuel Ayse
    Purpose: To determine the reasons of high serum serum transaminases levels and show the differences according to age and aetiology. Method: During the three years period, 250 cases with elevated serum transaminase levels among the children who hospitalized with various reasons were included to this study. The aetiological factors which caused high serum transaminase levels were classified according to the age groups (newborn, infants and older children). The mean serum transaminase levels were also determined according to aetiological factors. Results: In newborn period, most of the hipertransaminasemia causes were idiopathic. The most frequent pathological causes were perinatal asphyxia, haemolytic diseases and non-hepatitis infections, respectively. The most frequent causes of hipertransaminasemia were drug usage and non-hepatic infections in infancy period, while infectious hepatitis and drug usage were in older children. Among all of the groups, maximum transaminase levels were observed in the patients with infectious hepatitis. Interestingly, in some cases with abdominal blunt trauma, hypertransaminasemia were determined without hepatic injury. Conclusion: The ages and enzyme levels are important for the differential diagnosis of hipertransaminasemia and it should be taken into consideration that high serum transaminase levels could be obtained, even direct hepatic damage had not been observed.