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    Hypertrophic osteoarthropathy associated with lung cancer: a case report
    (Kare Publ, 2007) Ozen, Alaattin; Saynak, Mert; Kocak, Zafer; Bayir-Angin, Gulden; Uregen, Burcu; Cosar-Alas, Rusen; Cicin, Irfan
    Malignant neoplasms are sometimes associated with a variety of paraneoplastic rheumatic syndromes. Hypertrophic osteoarthropathy is one of these syndromes and the vast majority of cases are associated with intra thoracic neoplasms mainly broncogenic cancer. Hypertrophic osteoarthropathy (HOA) is characterized by clubbed fingers and periosteal new bone formation. Etiologically, it can be divided into primary and secondary HOA. The major clinical manifestation was severe bilateral leg pain. The pathogenesis of the disease remains unclear. Bone scintigraphy is a sensitive method to detect HOA. In this case, a 49-year-old man who had hypertrophic pulmonary osteoarthropathy associated with advanced stage non-small cell lung carcinoma is presented and a review of the literature is performed.
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    Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature
    (Humana Press Inc, 2007) Yurut-Caloglu, Vuslat; Caloglu, Murat; Ozyilmaz, Filiz; Saynak, Mert; Cosar-Alas, Rusen; Karagol, Hakan; Bayir-Angin, Gulden
    Adenoid cystic carcinoma is the second most common malignancy of the major and minor salivary glands after mucoepidemoid carcinoma. The risk of distant metastases is approximately 20-50%. Although bone, the central nervous system and the other organs may become involved, the lungs are favored sites for metastases. Skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the parotid gland are extremely rare. In this case, a 40-year-old man with lung and bone metastases followed by skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the right parotid gland is presented.
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    Recurrent solitary fibrous tumor of the pleura: significant response to radiotherapy
    (Humana Press Inc, 2010) Saynak, Mert; Bayir-Angin, Gulden; Kocak, Zafer; Oz-Puyan, Fulya; Hayar, Murat; Cosar-Alas, Rusen; Karamustafaoglu, Altemur
    Solitary fibrous tumor (SFT) of the pleura is an uncommon neoplasm with non-specific symptoms and non-pathognomonical radiological findings. Surgery allows establishment of a definitive diagnosis as well as a cure of the disease. The role of radiotherapy or chemotherapy in the management of the disease is unclear because of the rarity of the disease and the successful results of the surgical treatment. Long-term clinical follow-up may be useful for the patients with SFT because of the potential adverse biological behavior of this tumor, which may lead to repeated recurrences and/or malignant transformation. We reported a 66-year-old woman with recurrence of SFT in the right lung, which had significant response to external thoracic radiotherapy.