Yazar "Aylanc, Hakan" seçeneğine göre listele
Listeleniyor 1 - 6 / 6
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Evaluation of pituitary function in cases with the diagnosis of pediatric mild traumatic brain injury: Cross-sectional study(Medknow Publications & Media Pvt Ltd, 2016) Aylanc, Hakan; Tutunculer, Filiz; Sut, NecdetBackground: This study was to determine whether pituitary dysfunction occurs after head trauma in children or not and which axis is affected more; to define the association of pituitary dysfunction with the severity of head trauma and duration time after the diagnosis of head trauma. Materials and Methods: In this study, 24 children who were diagnosed with head trauma were evaluated regarding pituitary dysfunction. In all cases, after 12 h fasting, serum cortisol, fT(3), fT(4), thyroid-stimulating hormone, prolactin, insulin-like growth factor-1, serum sodium, urine density, follicle-stimulating hormone, luteinizing hormone, in female cases E-2, in male cases, TT levels were determined. Results: Mean age of children was 9.5 +/- 3.1 years, 14 children (58.3%) had mild, 9 children (37.5%) had moderate, and 1 children (4.2%) had severe head trauma according to the Glasgow coma scale. Mean duration time after head trauma was 29.4 +/- 9.8 months. In all cases, no pathologic condition was determined in the pituitary hormonal axis. In one children (4.2%), low basal cortisol level was found. There were no children with hormonal deficiency in this study. Conclusion: Although pituitary dysfunction after head trauma may develop in the early period, some may present in the late period; therefore, all cases should be followed up at outpatient clinics for a longer period.Öğe Fatal Acute Diclofenac-Induced Rhabdomyolysis in A Pediatric Patient(Galenos Publ House, 2011) Guzel, Ahmet; Biner, Betul Orhaner; Karasalihoglu, Serap; Aylanc, HakanDiclofenac, a widely used nonsteroidal anti-inflammatory drug, has been reported to cause fatal drug-induced rhabdomyolysis very rarely. We report a case of a 13-month-old girl who developed fatal rhabdomyolysis after administration of intramuscular diclofenac for relief of pain caused by a scalding burn injury. Rhabdomyolysis due to diclofenac has not been reported in children. Here, we present the first case report to demonstrate rhabdomylysis secondary to diclofenac administration.Öğe Indications for Brain Computed Tomography and Hospital Admission in Pediatric Patients with Minor Head Injury: How Much Can We Rely upon Clinical Findings?(Karger, 2009) Guzel, Ahmet; Hicdonmez, Tufan; Temizoz, Osman; Aksu, Burhan; Aylanc, Hakan; Karasalihoglu, SerapObjectives: The aim of this study was to describe the characteristics of patients with a minor head injury (MHI) who were admitted to a pediatric emergency unit and to identify the clinical signs and symptoms that most reliably predict the need for cranial computed tomography (CCT) and hospital admission following MHI. Methods: All patients were retrospectively evaluated according to age, gender, details of injury, presenting symptoms, physical examination findings, radiological investigations ordered and results, length of stay, outcome of the injury and hospitalization rates. Results: The factors affecting indications for computed tomography and hospitalization were retrospectively analyzed in 916 patients - 585 males and 331 females, aged between 1 month and 15 years (mean: 5.01 +/- 3.58 years), with MHI. A multivariate analysis revealed significant correlations between CCT abnormalities and Glasgow Coma Scale scores of 13 or 14, headache, posttraumatic amnesia, blurred vision, cephalohematomas, periorbital ecchymoses, otorrhea and abnormal neurological findings. CCT abnormalities were identified in 67 (19.8%) of the 338 CCT scans. Twenty of the 67 patients (29.9%) with CCT scan abnormality had no clinical signs. Of all cases, 125 (13.6%) were hospitalized, 617 (67.4%) were treated as outpatients, and 174 (19.0%) left the emergency department based on a personal decision. Conclusion: Some clinical risk factors can be used as predictors of abnormalities in CCT scans following MHI, but the absence of such clinical findings does not exclude the possibility of intracranial injuries. Copyright (C) 2009 S. Karger AG, BaselÖğe Residents and interns in the 3 university hospitals: their knowledge of and attitudes to drug allergy(Asia Pacific Assoc Allergy, Asthma & Clinical Immunology, 2020) Ozdemir, Pinar Gokmirza; Kizilca, Ozgur; Aylanc, Hakan; Celik, Velat; Beken, Burcin; Akbulut, Simge Dilan; Yazicioglu, MehtapBackground: Previous studies revealed there are many gaps in the awareness and knowledge regarding the diagnosis and management of drug allergy (DA) among various health-care professionals. Objective: To assess the knowledge, attitudes, and practices towards DA among residents and interns of 3 university hospitals in the region of Trakya (Thrace), Turkey. Methods: A cross-sectional survey was conducted at university hospitals of 3 cities in the Trakya region: 1. Trakya University Medical Faculty, Edirne (n = 405), 2. Namik Kemal University Medical Faculty, Tekirdag (n = 114), and 3. Canakkale 18 Mart University Medical Faculty, Canakkale (n = 111). A Turkish questionnaire was developed based on previous published studies. Results: The majority of participants (67%) had not received education on DA as a separate subject during their medical education. Less than a third (28.3%) of all respondents were satisfied with their knowledge concerning patients with clinical signs of DA. Of the 6 knowledge questions on DA, the average score for the study was 3.51 out of 6 (58.5%). Residents had a higher knowledge score (3.93 +/- 1.1) compared with interns (3.05 +/- 1.2) (p < 0.001). The lowest percentage of correct answers were in response to questions on laboratory confirmation of drug-related anaphylaxis (14.5%) and the possibility of penicillin toleration in patients with a history of penicillin allergy (11.8%). The majority of participants (92%) believe that medical doctors should be educated in DA. There were no significant correlations between taking DA histories and the frequency during daily practice of encountering patients. Conclusion: Our study revealed that DA knowledge and attitudes are not at satisfactory level among respondents, and we concluded the importance and necessity of reinforcement of DA education in pre- and postgraduate education of medical doctors.Öğe Thinner Intoxications in Childhood(Aves, 2009) Guzel, Ahmet; Kiziltepe, Cengiz; Aylanc, Hakan; Sayar, Esra; Karasalihoglu, Serap; Kavalci, CemilAim: Thinner is frequently used in industrial and house painting as thinner for paints. Although it has side affects which might affect vital functions associated with the central nervous system and respiratory system, acute intoxications due to thinner are commonly encountered in the childhood period. Materials and Methods: To evaluate patients who presented with the complaint of thinner drinking within the last 5 years. Results: Of 35 cases hospitalized in our clinic, 24 (68.6%) were males, 11 (31.4%) were females. The median age of the patients was 2.3 +/- 1.3 years. On initial administration, 23 (65.7%) had nausea-vomiting, 12 (34.3%) had restlessness, nine (25.7%) had dyspnea and pulmonary rales on auscultation. During follow-up, fever developed in nine (25.7%) of the patients. There was leucocytosis in 21 (60%) of patients. Antibiotherapy was given to 13 (37.1%) of the cases. The median time for hospitalization was 2.7 +/- 1.7 days. Of the hospitalized patients, 80% were discharged in good health, while 20% left hospital before completion of theit therapy. Conclusion: There should be caution in the sale, preservation and use of substances like thinner the intoxication of which have effects on vital organs. In addition, educational seminars about this subject should be held.Öğe Validity of serum tau protein levels in pediatric patients with minor head trauma(W B Saunders Co-Elsevier Inc, 2010) Guzel, Ahmet; Karasalihoglu, Serap; Aylanc, Hakan; Temizoz, Osman; Hicdonmez, TufanBackground: The aim of this study was to investigate the relationship between intracranial injury and serum tau protein levels in pediatric patients with minor head trauma (NI HT). Methods: We included 60 pediatric patients with MELT (Glasgow Coma Scale [GCS], 14-15) and 28 control patients. The patients were divided into 3 groups as follows: those without (group 1) and with (group 2) intracranial lesions shown on cranial computed tomography (CCT) and the control group (group 3). Results: The mean serum tau protein level was 96.06 +/- 70.36 pg/mL in group I. whereas it was 112.04 +/- 52.66 pg/mL in group 2, with no statistically significant difference between the groups (p = .160). The mean serum tau protein levels between the study groups (group I and group 2) and control (38.52 +/- 29.01) were statistically significant (P < .001 and P < .001, respectively). The GCS score and pathologic condition in CCT were only influential variables on tau protein levels. Conclusions: We found that serum tau protein increased after M HT but did not distinguish between those with and those without intracranial lesions demonstrable on CCT. (C) 2010 Elsevier Inc. All rights reserved.