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    Coupling reverse osmosis and osmotic distillation for clarified pomegranate juice concentration: Use of plasma modified reverse osmosis membranes for improved performance
    (Elsevier Sci Ltd, 2019) Bagci, Pelin Onsekizoglu; Akbas, Meryem; Gulec, Haci Ali; Bagci, Ufuk
    In this study, a low pressure nitrogen plasma (LPNP) activation was implemented to modify the surface characteristics of a commercial thin film composite (TFC) polyamide reverse osmosis (RO) membrane. The free energy of interaction (Delta G(iwi)) results showed that the hydrophobic nature of untreated TFC RO membrane became considerably hydrophilic with the effect of LPNP treatment. Among various plasma powers and exposure times tested, a general decreasing trend was observed for the water contact angle with increasing plasma duration, reaching a minimum of 13.2 +/- 0.8 degrees for 90 W at 15 min. A remarkable increase in water flux of the LPNP modified RO membrane was observed throughout the RO process, which promoted higher soluble solids content (SSC) values in the concentrated juice at the same period of time with the plain one. The higher SSC values achieved by the modified RO membrane enabled 30% time-saving during further osmotic distillation process.
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    The other side of the coin: understanding noninvasive follicular tumor with papillary-like nuclear features in unifocal and multifocal settings
    (W B Saunders Co-Elsevier Inc, 2019) Canberk, Sule; Montezuma, Diana; Tastekin, Ebru; Grangeia, Diana; Demirhas, Mehmet Polat; Akbas, Meryem; Tokat, Fatma
    The recent description of noninvasive follicular tumor with papillary-like nuclear features (NIFTP) creates several diagnostic and therapeutic challenges for both the pathologist and the attending clinician. Given the concern about overtreatment of these neoplasms, the best way to manage the patients by a surgical procedure and postsurgical follow-up is still under discussion. We aimed to identify predictors of synchronous disease (eg, bilateral cancers) that can influence the appropriate type of surgery and long-term surveillance. We reevaluated the original diagnosis and the presence of contralateral lesions in 94 cases retrieved from our archives that were seen between 2010 and 2017. In 74 cases, the diagnosis was NIFTP, and in 20 cases, the diagnosis was infiltrative follicular variant of papillary thyroid carcinoma (IFVPTC). Bilateral disease was found in 17% of the cases. In 13 (18%) of those cases, NIFTP was the primary lesion, and in 3 (15%), it was IFVPTC. The contralateral disease was predominantly invasive: 6 cases of micropapillary carcinoma, 5 of papillary thyroid carcinoma, 3 of IFVPTC, and 2 of NIFTP. Despite the higher frequency of contralateral disease in NIFTP, there was no statistically significant difference with IFVPTC. In the patients with multifocal NIFTP, 2 (15%) of the contralateral malignancies showed microscopic extrathyroidal extension (P < .05). We conclude that close monitoring of the contralateral lobe is appropriate in patients with FVPTC, particularly NIFTP, if they are not submitted to total thyroidectomy. (C) 2018 Elsevier Inc. All rights reserved.