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Öğe Assessment of Patients with von Willebrand Disease with ISTH/BAT and PBQ Scores(Galenos Yayincilik, 2020) Apak, Fatma Burcu Belen; Umit, Elif Gulsum; Zengin, Yagmur; Evim, Melike Sezgin; Unal, Ekrem; Ozbas, Hasan Mucahit; Acipayam, Can[Abstract Not Available]Öğe EARTHQUAKE DISASTER AND ITS' ACUTE EFFECT ON PEDIATRIC HEMATOLOGY AND ONCOLOGY.IN TURKIYE; TURKISH PEDIATRIC ONCOLOGY GROUP-TPOG QUESTIONARE STUDY(Wiley, 2023) Tacyildiz, Nurdan; Ozdemir, Sonay Incesoy; Kupeli, Begul; Cemaloglu, Mustafa; Acipayam, Can; Oncel, Kahraman; Akinel, Ayse Nur[Abstract Not Available]Öğe The Results of Hemoglobinopathy Screening in Hatay, the Southern Part of Turkey(Derman Medical Publ, 2016) Oktay, Gonul; Acipayam, Can; Ilhan, Gul; Karal, Yasemin; Sakalli, Gulten; Yilmazoglu, Nurullah; Basun, SunaAim: beta-Thalassemia and hemoglobinopathies are common genetic disorders in Turkey, Because of this reason, either anemic people or couples before marriage are investigated for hemoglobinopathies routinly. In this retrospective study, our aim was to determine the frequency of p-thalassemia and hemoglobinopathies in Hatay, which is located in the southern part of Turkey. Material and Method: In this study, data from 70226 individuals, admitted to Antakya State Hospital Hemoglobinopathy Center in Hatay, both for the reason of anemia and before marriage investigations, were evaluated between January 2006 and October 2012. The blood samples were collected into EDTA-containing tubes and hematological parameters were analyzed using a Sysmex XT-2000i Hematology Analyzer. High performance liquid chromatography technique was used to determine the type of hemoglobin. Results: The frequency of hemoglobinopaties were 5% beta-Thalassemia trait, 6,3% sickle cell trait, 12.9% alpha-thalassaeiria trait? and 4.2 Pb other abnormal hemoglobinopaties variants. We detected 49 cases with homozygot p-thalassaemia, 60 cases with homozygot haemoglobin 5, 33 cases with HbH disease (thalassaemia intermedia) among all. Discussion: The frequency of p-thalassemia trait and other haernoglobinopathies in Hatay is found to be quite high as compared with other provinces in Turkey.Öğe Screening of Glucose-6-Phosphate Dehydrogenase Deficiency in Cord Blood(Derman Medical Publ, 2014) Acipayam, Can; Orhaner, Betul Biner; Karal, YaseminAim: Glucose-6-phosphate dehydrogenase deficiency is an important factor in etiology of pathologic neonatal jaundice. The aim of this study was to indicate the significance of screening glucose-6-phosphate dehydrogenase deficiency in the cord blood of neonates and the frequency of this deficiency in the etiology of neonatal hyperbilirubinemia. Material and Method: The study was performed consecutive 1015 neonates were included. Five hundred fifty six (54.8%) of them were male and 459 (45.2%) were female. The following parameters were recorded: Gender, birth weight, birth height, head circumference and gestational age. The glucose-6-phosphate dehydrogenase level of neonates were measured with quantitative method in cord blood. Also, hemoglobine, hematocrite, red blood cell count and blood group were measured. The following parameters were recorded in cases with jaundice: exchange transfusion, phototherapy, physiologic and pathologic jaundice, peak bilirubin day, maximum bilirubin level, total bilirubin level at the first day of jaundice, beginning time of jaundice. Results: Enzyme deficiency was detected in 133 (13.1%) of neonates and 76 (57%1 of them were male, 57 (43%)were female. Significant difference was detected in low glucose-6-phosphate dehydrogenase enzyme level with jaundice group for total bilirubin level at the first day of jaundice, maximum total bilirubin level and pathologic jaundice (p<0.05). Discussion: The ratio of glucose-6-phosphate dehydrogenase deficiency was found in Edirne in this study and this ratio was higher than other studies conducted in our country. For this reason, glucose-6-phosphate dehydrogenase enzyme level in cord blood of neonates should be measured routinely and high risk neonates should be followed up for hyperbilirubinemia and parents should be informed in our region.