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Öğe Assesment of Patient Satisfaction of Implantable Venous Port Catheter Use: a Survey-Based Study(Trakya Üniversitesi, 2017) Söyleyici, Begüm; Şenyiğit, Ece; İşkan, Nur Gülce; Yanık, FazlıAims: Implantable venous port catheter is a widely used clinical tool with plenty of objectives such as parenteral nutrition, taking blood sample, management of medicines used in chemotherapy. The aim of this study is to evaluate patient satisfaction regarding implantable venous port catheter for chemotherapy treatment.Methods: The data of 19 patients operated from March 2017 to June 2017 were analyzed as a survey based assessment in Trakya University Hospital Department of Thoracic Surgery. Age, gender, satisfaction of having an implantable venous port catheter, the level of pain during implantation, being informed before the operation, fear of having a complication due to the implantable venous port catheter, being uncomfortable about having an implantable venous port catheter and not liking the appearance of implantable venous port catheter were included on the survey. The type and stage of cancer, comorbidity and the vein which is a port catheter was implanted in were recorded from patient charts. Results: The mean age of participants was 61.44 ± 7.493 years. Out of all 10 (52.6%) were male and 9 (47.4%) were female. The most utilized side during insertion was right jugular vein (94.4%). Rectum cancer was the most diagnosed cancer type with six patients. The most seen cancer stage was found to be stage-4-IV (66.7%). Comorbidity was detected in 15 patients (83.3%). 89.5% of patients had indicated that they were informed enough before the procedure. 57.9% of the patients responded to question of fear of complication as “yes”. According to these responses, 52.6% of the patients emphasized their discomfort as “little”.Conclusion: This survey-based assessment study points out that most of the cancer patients are contented for being implanted with an implantable venous port catheter. Having an implantable venous port catheter is safer and easier way for cancer patients. Moreover, it gives patients more freedom of movementÖğe Assessment of the Awareness and Opinions of Turkish Medical Students Towards Violence Against Women: a Questionnaire-Based Study(Trakya Üniversitesi, 2021) Akay, Fatih Erkan; Kılıç, Ilgın; İşkan, Nur Gülce; Söyleyici, Begüm; Şenyiğit, Ece; Önal, F. GülsümAims: This study aims to evaluate the opinions of medical students about violence against women, the education they receive during medical school regarding violence against women, and how they would manage a case of violence victims if they were to encounter it in their medical careers. Methods: In this question- naire-based study, 610 medical students from 37 medical schools were approached, and their opinions towards violence against women were evaluated through an online questionnaire. Demographic data such as age and gender were also gathered. Students were grouped according to their gender (male and female) and study levels; 1st, 2nd, and 3rd grades were grouped as pre-clinical, whereas students in 4th, 5th, and 6th grades were grouped as clinical. In comparing para- metric variables, the Student’s t-test was used, whereas, in non-parametric variables, the Mann-Whitney U test was used. The Chi-square test was used in the comparison of categorical variables. Results: There was a statistically significant difference within both groups (gender and study levels) for questions 5 (Which of the following would you describe as violence? [Multiple answers are allowed.]) and 13 (Do you think female physicians are exposed to violence more?). Our results also demonstrate a statistically significant difference for questions 15 (Is it obligatory for a physician to keep a legal report for a female patient who has been admitted to the emergency department as a victim of violence), 16 (It is not obligatory for a physician to keep a legal report for a female patient who has been admitted to the emergency department as a victim of violence without her consent.), and 17 (A physician is not obliged to complete the physical examina- tion or continue the diagnosis-treatment process of a female patient who has been a subject of violence without her consent.) between pre-clinical and clinical groups, where the clinical group gave the most correct answers. Conclusion: In conclusion, our results gave us a perspective that clinical students' awareness and management of violence against women is higher than pre-clinical students'. These results may be attributed to two factors; lectures on violence against women or the experience students attain during their clinical practices. Female students were keener in participating in our study. Further prospective studies with equal gender distribution investigating the possible impact of lectures about violence against women on physicians' management of similar situations are needed.Öğe A Case Report: the Role of Gallium-68 Dotatate Pet Scan in Neuroendocrine Tumors(Trakya Üniversitesi, 2016) İşkan, Nur Gülce; Keyfoğlu, Mehmet Can; Altun, Gülay DurmuşAims: Neuroendocrine tumors are rare neoplasms which express high quantity of somatostatin receptors. Gallium-68 DOTATATE PET scan is used to detect these tumors. In this case presentation, it is aimed to show the role of Ga-68 DOTATATE PET scan in detecting neuroendocrine tumors. Case Report: Sixty-four-year-old female consulted Trakya University Hospital Department of Nuclear Medicine with a diagnosis of neuroendocrine tumors in her various visceral organs. Galium-68 DOTATATE PET scan was used to detect the lesions and afterwards peptide receptor radionuclide therapy with Lutetium (Lu)-177 DOTATATE was given to the patient. Conclusion: Galium-68 DOTATATE PET scan plays a major role in detecting neuroendocrine tumors with high accuracy.Öğe The Early Results of the Coronary Artery Bypass Surgery in Patients With Significant Left Main Coronary Artery Stenosis(Trakya Üniversitesi, 2016) Yumurtacı, Öznur; İşkan, Nur Gülce; Yüksel, VolkanAims: The aim of this study is to evaluate and interpret the pre-op demographic data, post-op results and the causes of mortality and morbidity of the patients who had coronary artery bypass surgery with left main coronary artery stenosis in Trakya University Hospital. Methods: The pre-operative characteristics, post-operative results and the causes of mortality and morbidity of the patients who had coronary artery bypass surgery with left main coronary artery stenosis in Trakya University Hospital between January 2014 and April 2016 were analyzed by using the data in the current electronic database of the hospital. The pre-operative, operative and post-operative characteristics were summarized using means ± standard deviation and minimum-maximum values in SPSS.Results: Out of total 33 patients who were included in the study, 8 (24.24%) of them were female, while 25 (75.75%) of them were male. The mean age of the population was 64.09 ± 8.35. In examination of EuroSCORE points, 28 (84.8%) of patients were at low risk grade, 4 patients were at middle risk grade and 1 of all was at high risk grade. After operations, stay time at the hospital was minimum 2, maximum 47 days. About 94% of the patients who included in this study had lt;48 hours intensive care unit time. In addition, the examination showed that we have only 2 (6%) patients who had post stroke history. Usage of intra-aortic balloon pump was limited with 5 (15.1%) patients. Conclusion: In the light of the results of this study, we could say that this study has a contribution by enlarging the data repository about left main coronary artery stenosis. Coronary artery bypass surgery is still the gold standard treatment in patients with significant left main coronary artery stenosis. These operations can be performed with acceptable morbidity and mortality ratesÖğe Evaluating Combined Effect of Naringin and Salicylic Acid on Colon Cancer Cell Culture(Trakya Üniversitesi, 2017) Gökçe, Kübra; İşkan, Nur Gülce; Türker, Nebiye Pelin; Kaşit, MaideAims: Colorectal cancer is the 3rd most common cancer in the world. It affects more than a million people and causes the death of half million people annually. Flavonoids are natural products belonging to plantae and some fungal organisms that recently have started to be popular for cancer research for its strong antioxidant, anticarcinogen and anti-tumor properties. Naringin is a special chemical compound of flavonoid groups in grapefruit and useful for its antioxidant and immunostimulatory properties. Salicylic acid is a stress-specific hormone that also has an anti-tumor effects on colorectal cancer. In this study, it is aimed to evaluate the effect of naringin, salicylic acid and their combination on colon cancer cells via gene expression profiles of apoptosis genes and anti-proliferative properties. Methods: HT29 colon cell culture was incubated in 37 C and 5% CO2. Salicylic acid, naringin and their combinations were applied seperetaly on 80% confluent cells in 11 different doses starting with 800 µM and going half of the previous. MTT survival test was performed at 24th and 48th hours after application. To see the effect on apoptosis and antioxidant pathway; apoptotic protease activating factor, B-cell lymphoma 2, B-cell lymphoma 2 associated X, B-cell lymphoma 2 - XL, Cytochrome C, Cellular inhibitor of apoptosis protein 1, Cellular inhibitor of apoptosis protein 2, Glyceraldehyde-3-phosphate dehydrogenas, Caspase 3, Livin, Survivin, p21, p27, p53 and X-linked inhibitor of apoptosis, Catalase, Glutathione peroxidase, Superoxide dismutase 1 and Superoxide dismutase 2 gene expressions were assayed on 24th and 48th hours by using real time PCR.Results: Single and combined application of naringin and salicylic acid decreased cell proliferation at both 24th and 48th hours. Results in 48th hours were more obvious. None of the applications caused an increase in number of cells in any applied dose. In the real time PCR analysis, the expressions of apoptosis inhibitor genes that play a crucial role in antioxidant pathway were increased. The increase was more distinct in the combination of naringin and salicylic acid.Conclusion: In this study, it is found that both salicylic acid and naringin cause a decrease in the number of colon cell culture. As for their combination it also worked well. The increase in apoptotic gene expression was exclusive. It can be said that naringin, salicylic acid and especially their combination can be a promising treatment as a supported option for colon cancer patients in the futureÖğe The Evaluation and Interpretation of the Most Common Intervertebral Discs in Cervical Hernias: a Retrospective Study(Trakya Üniversitesi, 2016) İşkan, Nur Gülce; Kurt, Cansu; Akşar, Aslıhan; Tekataş, AslanAims: In this study it is aimed to determine the most common intervertebral discs in cervical hernias and to discuss the possible causes of prevalence.Methods:The data of 110 patients who were diagnosed with cervical disc hernia in Trakya University Health Center for Medical Research Neurology Clinics EMG lab in between 2012 and 2015 was analyzed retrospectively by looking at the age, gender and herniated intervertebral disc. Chi- Square test was used to determine the frequency of the cervical disc hernia in intervertebral discs in both genders. Independent Samples T Test was used to determine the correlation between prevalence of herniated intervertebral discs, age and gender. Arithmetic mean ± standard deviation, number and percentages, median (minimum-maximum) were used as descriptive analysis.Results: Out of 110 patients, there were 60 males (52.3%) and 50 females (48.7%) with the mean age of 50.43 ±12.67, the youngest patient was 26 and the oldest was 82. The most involved disc was found to be C5-C6 (15 males with a percentage of 25% and 23 females with a percentage of 46%). Conclusion:The most common intervertebral disc in cervical hernia was detected as C5-C6. It may be because of the maximal extension and flexion, functional overloading and micro traumas which affect C5-C6 segmentÖğe The Evaluation of Musculoskeletal System Tumors and Tumor Like Lesions in Thrace Region(Trakya Üniversitesi, 2018) Şenyiğit, Ece; Söyleyici, Begüm; İşkan, Nur Gülce; Çifcibaşı, Hilal Sena; Göztepe, Aslı; Çiftdemir, MertAims: The aim of this study is to evaluate the data belonging to patients who were diagnosed with benign or malignant soft tissue and bone tumors and tumor-like lesions evaluated by musculoskeletal tumor study group of Trakya University Faculty of Medicine in between January 2013 and June 2017 and the relationship between the frequency of benign, malignant bone and soft tissue tumors and tumor-like lesions, with the patients’ age and gender. Methods: The data of 687 patients who were evaluated by the musculoskeletal tumor study group of Trakya University Faculty of Medicine between January 2013- June 2017 were analyzed retrospectively. All of the data was analyzed by using SPSS. Chi-square analysis was used to obtain categorical data in order to point out the distribution of age and gender of patients with musculoskeletal system tumors and tumor-like lesions. Results: The number of patients over the period from January 2013 to June 2017 was 687. The number of patients who were evaluated by biopsy and acquired histopathologic confirmation of their condition was 341. The mean of patients’ ages was 44.3±21.4 (4-92). Among 341 patients, 106 (47.1%) patients were female and 119 (52.9%) patients were male. The mean of females’ ages was 43.7±20.4 (4-92). The mean of males’ ages was 44.7±22.4 (5-90). Conclusion: Benign bone and soft tissue tumors were more common than malignant tumors. Benign bone tumors were predominantly seen in young adults. Our results was consistent with the literature however due to some patients who did not need a pathological sampling, our sample size was smaller than intended. With better archived information, more consistent results could be obtained in further studies.Öğe The Evaluation of Patients With Multiple Level Spinal Fractures Admitted to a Single Institution: a Retrospective Study(Trakya Üniversitesi, 2017) İşkan, Nur Gülce; Şenyiğit, Ece; Söyleyici, Begüm; Çiftdemir, MertAims: The aim of this study is to evaluate the data of the patients who are diagnosed with multiple level spinal fracturesand to find out the most common level of fractures. Furthermore, this data will be examined regarding patients’age, gender, fracture type, cause of the injury, and type of the treatment in order to get a baseline data to improvefuture outcomes.Methods: The data of 42 patients who were diagnosed with multiple spinal fractures in Trakya University Facultyof Medicine Department of Orthopedics and Traumatology in between 2012 and 2017 was analyzed retrospectively.In order to understand the incidence of multiple spinal fractures in both genders, type of the treatment and cause ofthe injury, descriptive analysis as arithmetic mean ± standard deviation, number and percentages, median (mini¬-mum-maximum) were used.Results: There were 42 patients including 32 (76.2%) men and 10 (23.8%) women with a mean age of 41 years.The most common level of injury was T12 (17.5%). The incidence of T11-L1 fractures is 62.1%. 20 (47.6%) of thefractures were caused by motor vehicle accidents. 26 patients were treated surgically and 13 patients had conservativetreatment.Conclusion: Multiple level spinal fracture is a very important clinical problem. It is seen mostly in men andmiddle-aged population. Thoracolumbar transition (T11-L2) is the most affected region due to the biomechanicsof vertebral column. The most common causes of the multiple spinal fractures are motor vehicle accidents and falls.Management of multiple level spinal fractures are based on surgical or conservative treatment modalities. Choosingthe correct treatment option for a patient with multiple level spinal fractures depends on several factorsÖğe Incidental Detection of Previously Unknown Breast Cancer on Tc-99M Mibi Scintigraphy(Trakya Üniversitesi, 2021) İşkan, Nur Gülce; Orun, Şeyma Gizem; Gökdemir, Ezgi; Altun, Gülay DurmuşAims: Tc-99m methoxyisobutylisonitrile scintigraphy is a diagnostic method commonly used for cardiac perfusion imaging. It is also used for parathyroid, lung, breast, thyroid, brain, melanoma, lymphoma, bone, and soft tissue primary and secondary tumors imaging. Our case aims to report a breast cancer incidentally revealed by Tc-99m methoxyisobutylisonitrile scintigraphy. Case Report: A 49-year-old female patient was admitted to the cardiology depart- ment with atypical angina. Tc-99m methoxyisobutylisonitrile scintigraphy showed myocardial perfusion was within normal limits but a focal uptake was detected in the lateral superior quadrant of the left breast. Ultrasonography detected a lesion with irregular borders in the outer quadrant of the left breast and a lymph node with increased thickness of the cortex in the left axilla. Magnetic resonance imaging showed a mass with a spiculated contour in the outer quadrant of the left breast and lymph nodes with increased cortex thickness in both axillae. By the histopathologic examination, the specimen was diag- nosed with invasive ductal carcinoma. Conclusion: Although Tc-99m methoxyisobutylisonitrile scintigraphy is mainly used for myocardial perfusion imag- ing, the entire image area should be examined in detail and further investigation should be done for incidental focal lesions that were previously undetected.Öğe Otoscopic Examination(Trakya Üniversitesi, 2018) Kef, Berkay; İşkan, Nur Gülce; Kef, KemalAbstract: Ear related diseases are common in both otolaryngology clinics and family practice since all age groupscan get affected. Due to the frequency and the range of diseases of the ear, it is very important to carry out a thoroughexamination and make a correct diagnosis. Otoscopes are very useful tools used for otoscopic examination.Although head mirrors and head lambs can be used for the examination of the ear, otoscopes provide a better fieldof vision and a more detailed sight. There are two main types of otoscopes; portable and wall-mounted. However, theexamination should not be limited to the outer ear. It is the examiner’s responsibility to check the area around the earfor abnormalities. Otoscopic examination is a convenient method for making a correct diagnosis. Therefore, everymedical doctor should be able to perform a proper otoscopic examination and make a correct diagnosis.Öğe Periosteal Chondroma of the Femur: a Case Report(Trakya Üniversitesi, 2018) Şenyiğit, Ece; İşkan, Nur Gülce; Çiftdemir, MertAims: Periosteal chondroma is a rare and benign cartilage tumor seen mostly in long bones and in patients under30 years of age. In this case report, it is aimed to present a 16-year-old female patient with a periosteal chondroma inthe distal femur.Case Report: A 16-year-old female patient was admitted to the hospital with the history of pain in her distal partof right thigh. A superficial cortical erosion with well-defined borders without any relation to the intramedullaryarea was seen in magnetic resonance imaging. The lesion was regarded as periosteal chondroma and marginal excisionwas performed.Conclusion: This case report shows the importance of the differential diagnosis in cortical lesions. Periostealchondroma may be considered when a patient has a history of long term pain in adolescent age group