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Öğe The factors which affect the number of tender points in fibromyalgia and chronic widespread pain patients who did not meet the ACR 1990 criteria for fibromyalgia(Bmj Publishing Group, 2004) Pamuk, ÖN; Çakir, N[Abstract Not Available]Öğe Findings of pulmonary involvement on HRCT in turkish rheumatoid arthritis patients and contributory factors(Bmj Publishing Group, 2005) Koker, IH; Pamuk, ÖN; Tuncbilek, N; Karlikaya, C; Çakir, N[Abstract Not Available]Öğe Henoch-Schonlein purpura in two brothers imprisoned in the same jail(Clinical & Exper Rheumatology, 2004) Çakir, N; Pamuk, ÖN; Dönmez, SWe Present two brothers who came to us with similar complaints within a two-month interval and who were diagnosed is having Henoch-Schonlein purpura. Interestingly, the two brothers were prisoners in the same jail. In addition, we shall review, the small number of familial Henoch-Schonlein purpura cases that have been reported in the literature to date. Our two Patients exhibited arthritis and/or arthralgia, purpuric skin lesions, abdominal pain and hematuria, and were treated with steroids. We did not detect the presence of any inciting agent and hypothesize that an undefined factor present in the shared environment might have triggered the disease in two subjects with a similar genetic background.Öğe Mitral valve vegetation and cerebral emboli in a primary antiphospholipid syndrome patient who had hepatitis C virus infection(Springer-Verlag, 2003) Pamuk, ÖN; Çakir, N; Soy, M; Aktoz, M; Çelik, Y; Akdemir, OWe report the case of 36-year-old woman who came to us with a history of recurrent miscarriages and who was later diagnosed as having primary antiphospholipid syndrome (PAPS) and chronic hepatitis C virus (HCV) infection. The patient was referred to us with generalised seizures; cranial MRI revealed multiple embolic infarcts in both frontal lobes and a focal cortical infarct in the left frontoparietal lobe. Her echocardiography showed mitral valve vegetation and insufficiency. The patient was put on oral anticoagulant therapy and during her 8-month follow-up period no thrombotic events occurred. We report this case because it was the first in which PAPS, valvular disease, a cerebral embolic event and HCV infection were coexistent in the same patient. We also review other cases in which there was valvular vegetation and a cerebral ischaemic event associated with PAPS.Öğe A patient with ankylosing spondylitis who presented with chronic necrotising aspergillosis -: Report on one case and review of the literature(Springer London Ltd, 2005) Pamuk, ÖN; Harmandar, O; Tosun, B; Yörük, Y; Çakir, NUpper lobe fibrobullous disease is a well-known finding in advanced stages of ankylosing spondylitis (AS). In this report, we present a 57-year-old male patient who was diagnosed with a right apical cavitary lesion after coming to us with the complaint of haemoptysis. The patient underwent upper lobe segmentectomy and an aspergilloma was detected. Histologic findings were in favour of necrotising Aspergillus pneumonia. It was interesting that the patient had not been diagnosed with AS before and presented initially with chronic necrotising Aspergillus pneumonia. In the literature, there are recently published series of pulmonary high-resolution computed tomography (HRCT) in AS which claim that parenchymal abnormalities are quite frequent. Although the clinical significance of these abnormalities is not known with certainty, it has been reported that they might be seen even in early-stage patients. It is suggested that the pulmonary involvement in AS might be affected by mechanical factors related to limitation of motion of the thoracic cage and also by parenchymal inflammation. Here, we review the series of pulmonary HRCT in AS patients.Öğe A patient with Behcet's disease who presented with simultaneous cardiac tamponade and central nervous system involvement(Springer-Verlag, 2004) Çakir, N; Pamuk, ÖN; Pekindil, G; Dogutan, H[Abstract Not Available]Öğe The prevalance of rheumatologic diseases in Havsa(Bmj Publishing Group, 2005) Çakir, N; Pamuk, ÖN; Dervis, E; Imeryuz, N; Uslu, H; Benian, Ö; Senocak, M[Abstract Not Available]Öğe The renal effects of the addition of low-dose aspirin to COX-2 selective and nonselective antiinflammatory drugs(Springer London Ltd, 2006) Pamuk, ÖN; Çakir, NObjective: We aimed to evaluate the effect on renal functions and blood pressure of the addition of low dose aspirin (LDA) to cyclooxygenase-2 (COX-2) inhibitors or nonselective NSAIDs. Methods: Two groups each containing 14 patients with one group using celecoxib and the other indomethacin regularly for at least 1 week were included into the study. Both groups were initially administered 100 mg/day (week 1), and later 300 mg/day (week 2) aspirin. Baseline and weekly serum creatinine, uric acid, electrolytes, creatinine clearance (CrCl) and blood pressure were obtained. Results: Contrary to the celecoxib group, in the indomethacin group, both after the first and the second weeks the mean serum creatinine increased and CrCl decreased when compared to baseline values (p values < 0.05). In the indomethacin group, when compared to baseline values systolic blood pressure was significantly higher after week 1 and uric acid level after week 2 (p values=0.01). The frequency of patients with a >= 20% decrease in CrCl at the end of week 2 was higher in the indomethacin group than in the celecoxib group (42.9% vs. 0%, p=0.016). The difference between the mean creatinine (p=0.017) and CrCl values (p=0.007) from baseline until after week 2 was more significant in the indomethacin group than in the celecoxib group. Conclusions: The addition of LDA to patients using indomethacin led to significant renal dysfunction. Subjects using celecoxib seem to have been protected from the renal side effects of LDA.Öğe Scleroderma in a patient with X-linked agammaglobulinaemia(Taylor & Francis As, 2004) Pamuk, ÖN; Pamuk, GE; Turgut, B; Çakir, N[Abstract Not Available]Öğe Unilateral phrenic nerve paralysis in a patient with Wegener's granulomatosis(Springer-Verlag, 2003) Pamuk, ÖN; Dogutan, H; Pamuk, GE; Çakir, NA 35-year-old male diagnosed with Wegener's granulomatosis (WG) in 1989 recently came to our hospital with the complaint of left lumbar pain. He was found to have left nephrolithiasis and left diaphragmatic elevation. Fluoroscopic study and electromyographic examination revealed findings compatible with unilateral phrenic paralysis. We could not detect any cause other than WG which could be responsible for the unilateral diaphragmatic paralysis. Although different types of lung involvement have been reported in WG, to our knowledge this is the first in which unilateral phrenic nerve paralysis and diaphragmatic elevation associated with WG have been diagnosed.Öğe The variation in chronic widespread pain and other symptoms in ribromyalgia patients.: The effects of menses and menopause(Clinical & Exper Rheumatology, 2005) Pamuk, ÖN; Çakir, NObjectives We determined the relationship between the menstrual cycle and fibromyalgia (FM) symptoms in premenopausal women. In addition, we compared the clinical features of FM patients diagnosed pre-and postmenopausally. Methods We included 80 premenopausal, and 72 postmenopausal patients with FM. All patients were questioned about the severity of their pain and symptoms of FM by using a visual analog scale (VAS). In addition, the patients were asked questions about symptoms of somatization, depression and anxiety. Postmenopausal subjects were asked about the change in their FM symptoms with the onset of menopause; and premenopausal subjects were asked whether their FM symptoms changed during the menses. In addition, 40 premenopausal patients were requested to fill in a diary about their FM symptoms using VAS throughout one menstrual cycle. Results Postmenopausal patients had more severe pain on VAS (p = 0.048). Of all the postmenopausal females, 25% said that their FM symptoms started with the onset of menopause and 26.4% said that the severity of their previous symptoms increased after menopause. Of all the premenopausal females, 45% admitted to higher pain severity and 57.5% to a higher fatigue severity during the menses. The patients who defined an increase in their symptoms during the menses were the ones with higher sleep disturbance scores, more somatization symptoms and more tender points (p values < 0.05). The results of the diaries revealed that the mean pain and fatigue scores in the menstrual and luteal phases were higher than the scores in the follicular and premenstrual phases (p values < 0.05). Conclusions The menstrual cycle and the onset of menopause affect pain and the severity of other FAI-related symptoms in approximately one half of the subjects.Öğe The variation of chronic widespread pain and other symptoms in fibromyalgia patients during menses(Bmj Publishing Group, 2004) Pamuk, ÖN; Çakir, N[Abstract Not Available]
