Makale Koleksiyonu
http://dspace.trakya.edu.tr/xmlui/handle/trakya/3740
Article Colleciton2024-03-29T13:16:29ZA Case Report: a Mother With Secondary Infertility
http://dspace.trakya.edu.tr/xmlui/handle/trakya/6295
A Case Report: a Mother With Secondary Infertility
Göztepe, Aslı; Güldağ, Mahmut Alper; Elter, Koray
Aims: Secondary infertility is a disease where women with a firstborn are not able to have a child again. In this casereport, we wanted to observe a whole process of a patient with secondary infertility and investigate the causes andwhether there are any solutions for it.Case Report:A 41-year-old female patient presented to the clinic with the complaint of not being able to get pregnant.First thoughts about the patient were focused on infertility however, she had a child before. Therefore, furtherinvestigations were needed. After the investigations, she was diagnosed with secondary infertility because no rationalreasons were able to clarify her disease.Conclusion: Nowadays, secondary infertility is still a major health problem and no medications or treatments areenough to resolve this problem. The most common theory is the H-Y antigen hypothesis, but still, there is not enoughevidence for this theory to be proven.
DergiPark: 481902; tmsj
2018-01-01T00:00:00ZMenopoz sonrası kadınlarda hormon replasman tedavi süreci ve reprodüktif faktörlerin kemik mineral yoğunluğu üzerine etkileri
http://dspace.trakya.edu.tr/xmlui/handle/trakya/5931
Menopoz sonrası kadınlarda hormon replasman tedavi süreci ve reprodüktif faktörlerin kemik mineral yoğunluğu üzerine etkileri
Balkanlı, Petek Kaplan; Özden, Gülşah; Tokuç, Burcu; Yüce, Ali M
Amaç: Menopoz sonrası kadınlarda hormon replasman tedavi (HRT) sürecinin ve parite, menopoz yaşı, menopoz süresi gibi reprodüktif faktörlerin kemik mineral yoğunluğu üzerine etkileri araştırıldı. Hastalar ve Yöntemler: Trakya Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Kliniği Menopoz Polikliniği'ne başvuran 322 menopoz sonrası kadının (ort. yaş 52.4±6.2; dağılım 38-76) yaş, reprodüktif öykü ve hormon replasmanı ile ilgili bilgileri arşivden çıkarıldı. Hastalar, östrojen kullanım süreleri ve halen kullanmakta olup olmadıklarına göre sınıflandırıldı ve bu özelliklerinin kemik mineral yoğunluğuna etkileri analiz edildi. Kadınların lomber vertebra, femur, trokanter ve wards kemik dansitometreleri DEXA (dual-energy X-ray absorpsiometri) yöntemiyle ölçüldü. Bulgular: Hormon replasman tedavisi kullanımı üç yıldan fazla olan menopoz sonrası kadınlardaki wards ve trokanter kemik mineral yoğunlukları, üç yıldan az olanlara göre anlamlı olarak yüksek bulundu. Vertebral kemik yoğunlukları, üç yılın üzerinde HRT kullananlarda hiç kullanmayanlara göre daha yüksek saptandı. Wards ve vertebral kemik yoğunluğu değerleri, halen HRT'yi kullanmakta olan ve üç yıldan daha uzun süredir kullananlarda hiç HRT kullanmamış kadınlara göre daha yüksek tespit edildi. Geçmişte HRT kullanıp sonradan bırakmış olan kadınlarda kemik mineral yoğunluğu değerleri hiç HRT kullanmamış olan kadınlardan farklı olmadığı bulundu.. Parite ve menopoz sonrasında geçen süre artışının kemik yoğunluğunu düşürdüğü görüldü. Sonuç: Vertebra ve kalça kemik mineral yoğunlukları, HRT kullanımının ancak üç yıl veya daha uzun süreli kullanımlarında ve HRT'nin kullanıldığı dönem içinde artmaktadır. Parite ve menopoz sonrası geçen süre ise osteoporoz riskini artıran faktörlerdir.; Objectives: The effects of hormone replacement therapy (HRT) and reproductive factors such as parity, age of menopause, and duration of menopause on bone mineral density (BMD) in postmenopausal women were investigated. Patients and Methods: Age, reproductive history and HRT data of 322 postmenopausal women (mean age 52.4±6.2 years; range 38- 76) who applied to the outpatient menopause clinic of Trakya University Medical Faculty were gathered from the medical archives of the outpatient clinic. Patients were grouped according to the duration and current status of estrogen therapy and the effects of these variables on BMD were analysed. Bone mineral densities of lumbar spine, femur, trochanter, and Ward's triangle sites were measured by Dual Energy X-ray Absorptiometry (DEXA). Results: Bone mineral densities of trochanter, and Ward's triangle sites of postmenopausal women who received HRT for more than 3 years were found to be significantly higher than those women who were treated for less than 3 years. Vertebral bone densities were significantly higher in postmenopausal women who received HRT for more than 3 years, compared to those women who were never treated with HRT. Ward's triangle and vertebral bone densities were significantly higher in postmenopausal women who received HRT for more than 3 years and those currently on HRT, compared to those women who never received HRT. BMD values of women who started but interrupted their HRTs, were similar to the values found in women who never received HRT. Increasing parity and duration of menopause were the factors that reduced BMD values. Conclusion: It appeared that BMD of hip and spine increased in postmenopausal women after the third or more years on HRT and during the period of treatment with HRT. Parity and duration of menopause were identified as factors which increase the risk of osteoporosis.
2007-01-01T00:00:00ZErken evre endometrium kanserinde eksik cerrahi sonrası laparoskopik pelvik lenf nodu diseksiyonu: Olgu sunumu
http://dspace.trakya.edu.tr/xmlui/handle/trakya/5870
Erken evre endometrium kanserinde eksik cerrahi sonrası laparoskopik pelvik lenf nodu diseksiyonu: Olgu sunumu
Kaplan, Balkanlı Petek; Güçer, Fatih
Erken evre endometrium kanserinde geleneksel laparotomik cerrahi evrelemenin yerine laparoskopik yaklaşım, güvenli ve etkin bir seçenek olarak sunulmaya başlanmıştır. Bu yazıda, erken evre endometrium kanseri nedeniyle başka bir merkezde eksik cerrahi uygulanan, daha sonra merkezimizde laparoskopik pelvik lenfadenektomi yapılan 39 yaşındaki bir hasta sunuldu. Laparoskopik lenfadenektomi, lenf nodu diseksiyonu gerektiren jinekolojik maligniteler için teknik olarak geçerli ve güvenli bir yöntem olarak görünmektedir; Laparoscopic surgery has been suggested as a safe and effective alternative to laparotomy for the treatment of early stage endometrial cancer. In this study, we presented a 39-year-old patient who underwent pelvic lymphadenectomy through laparoscopy at our center following incomplete surgery at another center for early stage endometrium cancer. Laparoscopic lymphadenectomy seems to be a safe and reliable method for gynecologic malignancies that require lymph node dissection.
2005-01-01T00:00:00ZThe Use of Human Epididymis 4 and Cancer Antigen 125 Tumor Markers in the Benign or Malignant Differential Diagnosis of Pelvic or Adnexal Masses
http://dspace.trakya.edu.tr/xmlui/handle/trakya/5488
The Use of Human Epididymis 4 and Cancer Antigen 125 Tumor Markers in the Benign or Malignant Differential Diagnosis of Pelvic or Adnexal Masses
Altıntaş, Zehra Nihal Dolgun; Kabaca, Canan; Karateke, Ateş; İyibozkurt, Cem; İnan, Cihan; Altıntaş, Ahmet Salih; Karadağ, Cihan
Background: Ovarian cancer is one of the highest mortality cancers in gynaecology. Discrimination of benign masses from malignant ones may sometimes become a challenge for the clinician since there is not a reliable tumour marker, thus some unnecessary, highly morbid operations can be performed. Aims: To explore the efficacy of human epididymis 4 (HE 4) and cancer antigen 125 (CA 125) markers in differentiating malignant and benign pelvic masses of ovarian origin and to identify the cut-off points for those markers. Study Design: Prospective study. Methods: Fifty-one patients who were diagnosed and planned to undergo surgery for ovarian mass between June 2008 and December 2008 were enrolled into this study. Preoperative venous blood samples were taken and frozen for marker investigation and final diagnoses were concluded by histopathological examination. After recruitment of all cases CA 125 and HE 4 levels were evaluated. Results: The statistical analysis did not indicate any statistically significant difference between the CA 125 levels of the patients with malignant and benign adnexal masses (p=0.105). The HE 4 levels of the patients with malignant adnexal masses were higher at a statistically significant level compared to the patients with benign adnexal masses (p=0.002). For HE 4 tumour marker and at the cut-off point of >25 pM, sensitivity was 1, specificity 0.40, positive cut-off value 0.19, negative cut-off value 1, accuracy 0.47 and positive likelihood ratio 1.65. Conclusion: Human epididymis 4 is a better diagnostic tool than CA 125 in benign-malignant discrimination of adnexal masses. The cut-off value of 25 pmol/L for human epididymis 4 will contribute to providing proper guidance to patients with adnexal masses and applying the proper treatment method.
2017-01-01T00:00:00Z